3,988 results match your criteria: "Midwestern University.[Affiliation]"

Attempted Removal of a Large Pheochromocytoma via a Robotic Approach.

Cureus

September 2024

Endocrine Surgery, Surgical Group of Arizona, Phoenix, USA.

A pheochromocytoma is a rare tumor of neuroendocrine origin that secretes hormones like epinephrine, norepinephrine, and occasionally dopamine. The most notable symptom of the release of catecholamines is exceedingly high blood pressure. A 45-year-old male presented with a symptomatic pheochromocytoma of large size.

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Histology of the internal reproductive organs of the female Arabian oryx (Oryx leucoryx).

PLoS One

October 2024

Department of Anatomy, College of Graduate Studies, Midwestern University, Glendale, Arizona, United States of America.

The Arabian oryx (Oryx leucoryx) is an antelope that is considered a "vulnerable" species. Lack of knowledge on the structure of its reproductive organs hinders the development of strategies to improve its reproduction. There is only one report on the gross anatomy of the female reproductive organs.

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Post-operative care for patients following surgical treatment of lymphedema.

Med Oncol

October 2024

Program in Physical Therapy, Departments of Orthopaedic Surgery, Obstetrics & Gynecology, Washington University School of Medicine, 4444 Forest Park Boulevard, Campus Box 8502, Saint Louis, MO, 63108, USA.

Surgical treatments are promising for the treatment of lymphedema. It is important for patients, healthcare providers, and lymphedema community to understand that surgical treatments currently are not a cure for lymphedema but have provided promising options for patients. Post-operative care for patients following surgical treatment of lymphedema is vital to optimize and sustain patient outcomes.

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Popular Skin-of-Color Dermatology Social Media Hashtags on TikTok From 2021 to 2022: Content Analysis.

JMIR Dermatol

October 2024

Department of Dermatology, University of Minnesota Medical School, 1-411 Phillips-Wangensteen Building, 516 Delaware St SE, MMC 98, Minneapolis, MN, 55455, United States, 1 612-625-8625.

TikTok is a social media platform that can educate users about dermatology, but this longitudinal analysis of skin of color-related TikTok hashtags from 2021 to 2022 suggests that nondermatologist influencers continue to dominate content creation, highlighting the need for more participation from board-certified dermatologists to actively counter misinformation and address potential disparities in skin-of-color health care.

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Article Synopsis
  • The study focuses on risk management and self-management strategies for breast cancer-related lymphedema (BCRL), emphasizing the need to align education on risk factors with evidence-based guidelines.
  • Researchers conducted a systematic literature review, analyzing 148 articles and narrowing it down to 37 relevant studies to evaluate the effectiveness of current educational practices and behavioral changes in preventing or reducing BCRL.
  • The findings suggest that the existing approach to educating patients on BCRL risks may not be sufficient, highlighting gaps in knowledge and the need for further research on risk factors and their influence on BCRL progression.
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Background: Periorbital dyschromia (POD) is a prevalent dermatologic problem with multifactorial etiology, making treatment outcomes inconsistent and unclear.

Objective: To evaluate and compose a comprehensive review of topical ingredients proven to be effective in the treatment of POD.

Materials And Methods: Scopus, PubMed, and OVID databases were searched in a span of 30 years through December 31, 2023, to identify articles with original findings of topical therapies for the treatment of POD.

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Background: Carotenoids are present throughout retina and body its dense deposition leads to an identifiable yellow spot in the macula. Macular pigment optical density (MPOD) measured in the macula is vital to macular well-being and high-resolution visual acuity. MPOD has also been associated with various health and disease states.

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Article Synopsis
  • The study aimed to understand the genetic factors of prostate cancer by analyzing 14 genes linked to cancer susceptibility using Next Generation Sequencing (NGS).
  • Key findings revealed pathogenic mutations in genes like BRCA1, BRCA2, and TP53, along with benign variations, highlighting their differing roles in cancer progression.
  • Functional tests showed that mutations in BRCA1 and BRCA2 were linked to lower expression levels and increased sensitivity to certain chemotherapy drugs, while mutations in TP53 did not notably affect drug response.
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Deep-time origin of tympanic hearing in crown reptiles.

Curr Biol

November 2024

Departamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Av. Bandeirantes 3900, Ribeirão Preto, São Paulo 14040-901, Brazil. Electronic address:

Article Synopsis
  • - The transition of tetrapods to terrestrial ecosystems around 375 million years ago marked a significant evolutionary step, driven by adaptations like the development of a tympanic ear that improved sound detection in air.
  • - Earlier theories claimed a single evolutionary origin for the tympanic ear in tetrapods, but recent studies indicate it evolved independently in amphibians, mammals, and reptiles, though it’s unclear how many times this occurred within reptiles.
  • - New research combines developmental and paleontological insights, suggesting that the tympanic membrane was likely present in a common ancestor of crown reptiles, arguing for a single evolutionary origin rather than multiple instances for tympanic hearing in modern reptiles.
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Article Synopsis
  • Herpes simplex virus (HSV) encephalitis is a serious neurological condition that can lead to temporal lobe damage and result in seizures and psychiatric symptoms, particularly affecting older adults.
  • A case study involving an older male patient revealed that he had new visual hallucinations and seizures, which led to a diagnostic journey that included CT and EEG tests, ultimately suggesting HSV encephalitis despite negative PCR results for the virus.
  • The patient improved significantly with antiviral and antiepileptic treatments, highlighting the importance of recognizing potential underlying causes of acute neuropsychiatric symptoms for timely and effective intervention.
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Article Synopsis
  • The American Association of Colleges of Pharmacy and the American Pharmacists Association formed a Gender Equity Task Force to investigate gender disparities in pay, responsibilities, and treatment among pharmacy faculty.
  • A survey sent to members revealed that 72% experienced gender inequity, with women and people of color disproportionately affected, although many men believed treatment was equitable.
  • The findings highlight significant perception gaps regarding gender equity, suggesting that colleges of pharmacy should work to raise awareness and assess gender inequity within their institutions.
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The origin of primates has long been associated with an increased emphasis on manual grasping and touch. Precision touch, facilitated by specialized mechanoreceptors in glabrous skin, provides critical sensory feedback for grasping-related tasks and perception of ecologically-relevant stimuli. Despite its importance, studies of mechanoreceptors in primate hands are limited, in part due to challenges of sample availability and histological methods.

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Context: Osteopathic manipulative medicine (OMM) is a unique skill set consisting of physical manipulations that treat the neuromusculoskeletal system. Although OMM can improve patient outcomes such as functionality and pain, as well as increase physician reimbursement, its use is declining. Barriers to its use include a lack of proficiency, support, reimbursement, and time.

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Heart failure is a common cardiovascular disease that affects older people and has a high rate of mortality. Treatment for heart failure has evolved in the past 10 years to include novel evidence-based agents as well as changes in how medications are initiated and up-titrated. Despite evidence of the importance of using four guideline-directed medications, older people are often undertreated with these lifesaving therapies.

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Objective: The purpose of this study was to examine the intrarater reliability and criterion validity of a digital goniometer for measuring cervical range of motion including an active sitting version of the cervical flexion rotation test, an important clinical measure for capturing upper cervical dysfunction.

Methods: A cross-sectional study (n = 18; 78% women) examined total cervical and upper cervical active ranges of motion (flexion, extension, side bending, rotation) measured concurrently using 3 measurement methods (a digital goniometer, the cervical range-of-motion instrument, and 3-dimensional motion analysis). Intraclass correlation coefficient (2,1), Pearson correlation coefficients (digital goniometer versus 3-dimensional motion analysis), and minimum detectable change were calculated.

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The prevalence of squamous cell carcinoma is increasing, and efforts that aid in an early and accurate diagnosis are crucial to improve clinical outcomes for patients. Cornulin, a squamous epithelium-specific protein, has recently garnered attention due to its implications in the progression of squamous cell carcinoma developed in several tissues. As an epidermal differentiation marker, it is involved in skin anchoring, regulating cellular proliferation, and is a putative tumor suppressor.

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Article Synopsis
  • - This study explored how the severity of processing speed impairment affects performance on the Rey 15-Item Test (RFIT) and its recognition variant, revealing that those with intact processing speed scored better than those with reduced or impaired speeds.
  • - Data from 285 neuropsychological assessments were analyzed, using various standardized tests to measure processing speed and other cognitive functions, with results showing significant predictive power from both verbal/visual memory and processing speed.
  • - While the RFIT tests showed good classification accuracy for individuals with intact processing speed, their effectiveness dropped significantly for those with impaired speeds, indicating that the RFIT may not be suitable for evaluating individuals with greater processing speed deficits.
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Background The neurological condition known as multiple sclerosis (MS) is crippling and has a complicated pathogenesis as well as a wide range of clinical symptoms, including fatigue, difficulty walking, numbness or tingling, muscle spasms and spasticity, weakness, vision problems, dizziness and vertigo, bladder and bowel dysfunction, cognitive impairment, and emotional changes. The complete scope of MS pathology cannot be fully captured by conventional magnetic resonance imaging (MRI) sequences, which has led to the investigation of sophisticated MRI methods for better diagnosis and treatment. Objective This study aims to evaluate the clinical relevance of advanced MRI sequences in multiple sclerosis.

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Background: Stigma and discrimination have been shown to be significant barriers to healthcare utilization and provider trust among sexual minority groups including BDSM and kink communities.

Aim: This exploratory study sought to better understand medical mistrust and experiences of discrimination in primary care settings and how these factors predict hiding kink-related injuries from healthcare providers.

Methods: A total of 301 individuals who self-identified as being a member of the BDSM community and engaged in BDSM-play activities completed an online survey.

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Case report: Localized coloproctitis caused by novel in a dog.

Front Vet Sci

September 2024

Fungus Testing Laboratory, Department of Pathology & Laboratory Medicine, University of Texas Health Science Center, San Antonio, TX, United States.

A 6-year-old male neutered boxer mix canine was presented for a one-month history of dyschezia, hematochezia, and constipation. Colonoscopy and endoscopic biopsies revealed non-specific lymphoplasmacytic, eosinophilic colitis. Despite pursuing various therapies over a 3.

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Pulmonary coccidioidomycosis is a relatively common fungal disorder in dogs that have lived in or traveled to endemic regions and fluconazole is a common antifungal treatment. Liver enzymopathy can occur with fluconazole administration, but the frequency of occurrence nor potentially associative factors have been explored in dogs with pulmonary coccidioidomycosis. Therefore, our objectives were to describe the occurrence and magnitude of liver enzyme activity (LEA) elevation in dogs with pulmonary coccidioidomycosis during treatment with fluconazole and identify variables associated with liver enzymopathy.

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Article Synopsis
  • Coccidioidomycosis poses a significant risk to lung transplant recipients, especially when they move to areas where the fungus is common, like Phoenix, Arizona.
  • A study involving 40 lung transplant patients showed that most were not on antifungal prophylaxis upon relocating, but 96% started azole therapy soon after.
  • Only one case of coccidioidomycosis was recorded during the follow-up period, indicating that azole prophylaxis is effective at reducing the risk of this disease in high-risk populations.
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Contributions and future potential of animal models for geroscience research on sensory systems.

Geroscience

September 2024

Department of Anthropology and Archaeology, University of Calgary, 2500 University Dr NW, Calgary, AB, T2N 4N1, Canada.

Sensory systems mediate our social interactions, food intake, livelihoods, and other essential daily functions. Age-related decline and disease in sensory systems pose a significant challenge to healthy aging. Research on sensory decline in humans is informative but can often be difficult, subject to sampling bias, and influenced by environmental variation.

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The curious skink, Carlia ailanpalai Zug, occurs in the main group of the Admiralty Islands of Papua New Guinea but has also successfully invaded Guam, the Marianas, Yap, and Kosrae. A single coccidian, Eimeria zugi McAllister, Duszynski, Fisher, & Austin, 2013 was described from C. ailanpalai from Papua New Guinea.

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