Statin-associated myasthenia gravis: report of 4 cases and review of the literature.

A few recent individual case reports have suggested that a myasthenic syndrome may be associated with statin treatment, but this association is not well described. We report 4 patients who developed symptoms of myasthenia gravis within 2 weeks of starting treatment with a statin drug. In 1 case the drug appears to have exacerbated underlying myasthenic weakness, whereas in the other 3 cases, de novo antibody formation appears to be most likely.

Dolichoectatic arterial compression of the anterior visual pathways: neuro-ophthalmic features and clinical course.

Aim: To characterise the clinical findings and natural history of anterior visual pathway compression by dolichoectatic intracranial vessels.

Methods: A retrospective case review of patients evaluated in an outpatient neuro-ophthalmology clinic.

Results: 10 patients with this condition were identified.

Superior segmental optic nerve hypoplasia.

A visually asymptomatic 27-year-old man was found to have inferior altitudinal visual field defects binocularly. Ophthalmoscopy revealed superior segmental optic pallor with superior nerve fiber layer atrophy, nicely highlighted in red-free photographs. The patient's mother had insulin-dependent diabetes mellitus.