3 results match your criteria: "Midlands Clinic[Affiliation]"

Article Synopsis
  • The DecisionDx-Melanoma test analyzes 31 genes to determine the risk of metastasis in primary cutaneous melanoma patients, classifying them into low (Class 1) or high (Class 2) risk categories.
  • A study reviewed the medical charts of 156 melanoma patients and found that 53% of them had management changes based on the test results, with Class 2 patients showing more significant adjustments than Class 1.
  • The findings demonstrate that gene expression profiling affects clinical decision-making, as most management changes aligned with the patients' risk categories, although follow-up data to assess long-term impact was not available.
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Gouty tophi on the ear: a review.

Cutis

October 2013

Midlands Clinic, 705 N Sioux Point Rd, Dakota Dunes, SD 57049, USA.

Although the classic location of gouty tophi is the great toe (podagra), gouty tophi of the ear also is common and is worth including in the differential diagnosis in patients presenting with ear lesions. Other entities presenting as papules or nodules on the ear include chondrodermatitis nodularis helicis (CNH), actinic keratosis, basal cell carcinoma, squamous cell carcinoma, verruca vulgaris, amyloids, rheumatoid nodules, and elastotic nodules. If tophaceous gout is suspected, alcohol fixation of the biopsy specimen is preferable, as it enables visualization of characteristic needle-shaped urate crystals.

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