451 results match your criteria: "Mid Yorkshire Hospitals[Affiliation]"

Introduction: Burn wound management is challenging, especially in paediatric patients when optimising outcomes. Superficial burns are generally managed conservatively with dressings; however, frequent dressing changes can be a source of pain and discomfort. Cellulose dressings mitigate these problems, and current reports in the literature have demonstrated positive outcomes when compared against routine dressing types.

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Threshold modeling for antibiotic stewardship in Oman.

Am J Infect Control

November 2024

Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK; Pharmacy Department, Mid Yorkshire Hospitals NHS Trust, Wakefield, UK. Electronic address:

Background: Antimicrobial stewardship supports rational antibiotic use. However, balancing access to antibiotic treatment while controlling resistance is challenging. This research used a threshold logistic modeling approach to identify targets for antibiotic usage associated with carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Klebsiella pneumonia, and extended-spectrum β-lactamases-producing Escherichia coli incidence in hospitals.

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Introduction: Peer-reviewed journals are commonly used by health professionals, including radiographers to disseminate their research products. Understanding patterns like productivity and collaboration of authorship is crucial, enabling relevant stakeholders to chart better directions for professional journals. This bibliometric analysis updates previous works to explore current trends in authorship and collaborations within radiography professional journals.

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Background: This study investigated the application of Duty of Candour (DoC) legislation in the context of post-colonoscopy colorectal cancers (PCCRCs). DoC mandates transparent disclosure of notifiable safety incidents to patients in the English National Health Service, including incidences leading to severe or moderate harm. This study aimed to analyze the application of DoC in PCCRCs, improve understanding of the legislation, and identify challenges in DoC implementation.

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We aimed to describe the safety and tolerability of initiation of sodium-glucose cotransporter 2 inhibitors (SGLT2i) during hospitalisation with heart failure, and the frequency of, and reasons for, subsequent discontinuation. In total, 934 patients who were not already prescribed a SGLT2i were hospitalised with heart failure, 77 (8%) were initiated on a SGLT2i a median of five (3-8.5) days after admission and two (0.

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Sex dependence of postoperative pulmonary complications - A post hoc unmatched and matched analysis of LAS VEGAS.

J Clin Anesth

December 2024

Amsterdam University Medical Center, Department of Anaesthesiology, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands; Amsterdam University Medical Center, Department of Intensive Care, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands.

Article Synopsis
  • The study aimed to investigate whether there are differences in postoperative pulmonary complications (PPCs) between males and females following surgery under general anesthesia, using data from the LAS VEGAS study involving 146 hospitals across 29 countries.
  • A total of 9,697 patients were analyzed in two cohorts: an unmatched cohort (55.1% female, 44.9% male) and a matched cohort (50% female and male), finding no significant differences in PPC rates between the genders in both cohorts.
  • The study concluded that, in this international patient population, the incidence of PPCs did not differ significantly between males and females, as well as noting comparable hospital stays and mortality rates.*
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Article Synopsis
  • In 2018, the World Endoscopy Organization (WEO) established standardized methods to calculate post-colonoscopy colorectal cancer rates over three years (PCCRC-3yr), prompting a systematic review to assess global rates and associated risk factors.
  • The review analyzed studies from five databases and included eight studies totaling over 220,000 colorectal cancer cases, finding a pooled PCCRC-3yr rate of 7.5% that significantly decreased from 7.9% in 2006 to 6.7% in 2012.
  • Higher PCCRC rates were linked to specific risk factors, including inflammatory bowel disease, prior colorectal cancer, proximal cancer location, diverticular disease, and being female, undersc
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Pulmonary transit time is a predictor of outcomes in heart failure: a cardiovascular magnetic resonance first-pass perfusion study.

BMC Cardiovasc Disord

June 2024

Multidisciplinary Cardiovascular Research Centre, Department of Biomedical Imaging Science, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.

Background: Pulmonary transit time (PTT) can be measured automatically from arterial input function (AIF) images of dual sequence first-pass perfusion imaging. PTT has been validated against invasive cardiac catheterisation correlating with both cardiac output and left ventricular filling pressure (both important prognostic markers in heart failure). We hypothesized that prolonged PTT is associated with clinical outcomes in patients with heart failure.

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Introduction: Evidence based practice relies on availability of research evidence mostly through peer-reviewed journal publications. No consensus currently exists on the best hierarchy of research evidence, often categorised by the adopted research designs. Analysing the prevalent research designs in radiography professional journals is one vital step in considering an evidence hierarchy specific to the radiography profession and this forms the aim of this study.

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'Sustainability in the NHS': a novel method for teaching sustainable dentistry and quality improvement to dental core trainees.

Br Dent J

June 2024

Associate Postgraduate Dental Dean for Dental Core Training, NHSE Workforce, Training and Education, Yorkshire and the Humber, UK.

The practice of dentistry contributes to 3% of the carbon footprint of the NHS. As awareness and concern about climate change increases, all dental care professionals must play their part in reducing the environmental impact of the care they provide. This paper aims to describe a novel method of teaching, both the theory and practical application of sustainable dentistry, by integrating sustainable quality improvement methods into the existing management and leadership requirements of dental core training.

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Aims: Local authorities in England are responsible for public health and health promotion. This article sought to explore how research and decision-making co-exist in a local authority in England.

Methods: An Embedded Researcher was based within the local authority and used qualitative methodology to address the research aim.

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Article Synopsis
  • - The study examines the effectiveness of subtalar arthroereisis in treating stage 1 flexible progressive collapsing foot deformity (PCFD), focusing on clinical outcomes and the rate of implant removal.
  • - After evaluating 212 patients over an average of 2.5 years, significant improvements in pain and function were noted, with positive FAOS results across several categories, although a high implant removal rate of 48.1% due to persistent pain was also observed.
  • - The findings suggest that while subtalar arthroereisis can enhance patient outcomes, individuals should be informed about the possibility of needing further surgery to remove the implant.
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Inflammatory profile of lower risk myelodysplastic syndromes.

Br J Haematol

September 2024

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

The precise link between inflammation and pathogenesis of myelodysplastic syndrome (MDS) is yet to be fully established. We developed a novel method to measure ASC/NLRP3 protein specks which are specific for the NLRP3 inflammasome only. We combined this with cytokine profiling to characterise various inflammatory markers in a large cohort of patients with lower risk MDS in comparison to healthy controls and patients with defined autoinflammatory disorders (AIDs).

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Objective: Non-adherence to adjuvant endocrine therapy (AET) in women with breast cancer is common and associated with medication side-effects and distress. We co-designed an Acceptance and Commitment Therapy intervention (ACTION) to enhance medication decision-making and quality of life (QoL). We undertook a pilot trial of ACTION to inform the feasibility of a phase III trial, and to examine intervention acceptability.

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Rationale, Aims And Objectives: Critical incident debriefing is an occupational health tool for supporting healthcare workers following critical incidents. Demand for debriefing has increased following the Covid-19 pandemic. There is now a need for more trained debrief facilitators to meet demand, but there is a dearth of literature regarding how best to train facilitators.

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Objectives: Olfactory dysfunction (OD) is common and carries significant personal and societal burden. Accurate assessment is necessary for good clinical and research practice but is highly dependent on the assessment technique used. Current practice with regards to UK/international clinical assessment is unknown.

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Introduction: Bisphosphonates (BPs) are one of the most often used drugs to lower fracture risk in osteoporosis patients; nonetheless, BPs have been linked to atypical femoral fracture (AFF). Teriparatide (TPTD) is a parathyroid hormone analogue and anabolic drug that may accelerate fracture repair. TPTD has been considered as a possible treatment for AFF, particularly those caused by BP use.

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The use of compression therapy is known to be effective in the management of patients with venous leg ulceration and is commonly recommended as a first-line treatment. A rare but known complication of compression therapy is pressure damage to the limb, also referred to as bandage damage, which should be categorised as a medical device-related pressure injury. Patients should receive a comprehensive, holistic assessment before any compression therapy is applied.

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High failure rate after medial meniscus bucket handle tears repair in the stable knee.

Orthop Traumatol Surg Res

June 2024

Ramsay Santé, Hôpital privé Jean Mermoz, Centre Orthopédique Santy, FIFA Medical Center of Excellence, Lyon, France; Centre Orthopédique Santy, Lyon, France. Electronic address:

Article Synopsis
  • The study focused on the outcomes of patients who had isolated repairs of bucket handle tears in the medial meniscus, emphasizing that these procedures are crucial to avoid long-term osteoarthritis risks.* -
  • Out of 39 patients followed for an average of 77 months, 69% experienced failure requiring reoperation, but in over half of these cases, less meniscus tissue was removed during the reoperation than in the initial surgery.* -
  • Despite the high failure rate, patients showed significant improvements in clinical scores post-surgery, indicating that the procedures had beneficial effects on their knee function.*
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