2 results match your criteria: "Michigan2John D. Dingell VA Medical Center[Affiliation]"
Pancreatic Cancer Cell Lysis by Cell-Penetrating Peptide-MAGE-A3-Induced Cytotoxic T Lymphocytes.
JAMA Surg
November 2016
Wayne State University School of Medicine, Detroit, Michigan2John D. Dingell VA Medical Center, Detroit, Michigan.
MAGE-A3 with cell-penetrating domain as an efficient therapeutic cancer vaccine.
JAMA Surg
May 2014
Laboratory of Surgical Oncology and Developmental Therapeutics, Department of Surgery, Wayne State University, Detroit, Michigan2John D. Dingell VA Medical Center, Detroit, Michigan.
Importance: In conjunction with chemotherapy, immunotherapy with dendritic cells (DCs) may eliminate minimal disease burden by generating cytotoxic T lymphocytes. Enhanced cytosolic bioavailability of tumor-specific antigens improves access to human leukocyte antigen (HLA) class I molecules for more efficient cytotoxic T lymphocyte generation. Various cell-penetrating domains (CPDs) are known to ferry covalently linked heterologous antigens to the intracellular compartment by traversing the plasma membrane.
View Article and Find Full Text PDF