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Time sensitivity-corrected retention index: an enhanced metabolic index from 18F-FDG PET to differentiate between benign and malignant pulmonary nodules.

Nucl Med Commun

December 2014

aDepartment Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine, Royal Oak bCranbrook Educational Community, Bloomfield Hills, Michigan cUniversity of Tennessee, Knoxville, Tennessee, USA.

The aim of the study was to evaluate pulmonary nodules (PNs) by incorporating time sensitivity (S) factor in the retention index (RI) and compare with the traditional fixed interval method. After obtaining approval from the Human Investigations Committee, 97 PNs from 81 patients (age=70±11) referred for dual-time fluorine-18 fluorodeoxyglucose PET (16.1±1.

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