2 results match your criteria: "Michigan Alzheimer's Disease Research Center - University of Michigan[Affiliation]"
Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.
J Am Heart Assoc
October 2023
Department of Biostatistics, School of Public Health Boston University Boston MA USA.
Article Synopsis
- * Findings validate previous associations, revealing that lower mtDNA CN correlates with a higher risk of coronary heart disease but within the context of no causal relationship established in either direction.
- * Strong evidence suggests that high low-density lipoprotein cholesterol influences mtDNA CN levels, indicating it may play a key role in the relationship between mtDNA CN and cardiovascular health.
Introduction: We used cultural neuropsychology-informed procedures to derive and validate harmonized scores representing memory and language across population-based studies in the United States and Mexico.
Methods: Data were from the Health and Retirement Study Harmonized Cognitive Assessment Protocol (HRS-HCAP) and the Mexican Health and Aging Study (MHAS) Ancillary Study on Cognitive Aging (Mex-Cog). We statistically co-calibrated memory and language domains and performed differential item functioning (DIF) analysis using a cultural neuropsychological approach.