Fully Synthetic Data for Complex Surveys.

When seeking to release public use files for confidential data, statistical agencies can generate fully synthetic data. We propose an approach for making fully synthetic data from surveys collected with complex sampling designs. Our approach adheres to the general strategy proposed by Rubin (1993).

Population-level administrative data: A resource to advance psychological science.

Population-level administrative data-data on individuals' interactions with administrative systems, such as healthcare, social-welfare, criminal-justice, and education systems-are a fruitful resource for research into behavior, development, and wellbeing. However, administrative data are underutilized in psychological science. Here, we review advantages of population-level administrative data for psychological research, with examples of advances in psychological theory arising from administrative-data studies.

Dual Biologic Therapy Induces Remission in Refractory Crohn's Disease With Vedolizumab and Ustekinumab.

Background: Despite advancements in the therapeutic armamentarium for Crohn's disease (CD), biologic and small molecule monotherapies are associated with sub-optimal response and remission rates. Utilizing dual biologic therapy (DBT) holds the potential to increase efficacy in the treatment of refractory or partially responsive CD. Evidence pertaining to this strategy remains limited.

Addressing the Underrepresentation of African American Mental Health Professionals: A Call to Action.

The mental health workforce in the United States faces a significant challenge: a stark underrepresentation of African American practitioners. This disparity reflects broader issues of racial inequality in healthcare and has far-reaching implications for mental health care delivery, particularly within Black communities. This perspective examines the contributing factors to this underrepresentation, explores its consequences on patient care and research, and proposes strategies to increase diversity in the field.

Temporal variations in and predictive values of ABG results prior to in-hospital cardiac arrest.

In-hospital cardiac arrest (IHCA) has been understudied relative to out-of-hospital cardiac arrest. Further, studies of IHCA have mainly focused on a limited number of pre-arrest patient characteristics (e.g.

Landscapes-a lens for assessing sustainability.

Context: There are urgent calls to transition society to more sustainable trajectories, at scales ranging from local to global. Landscape sustainability (LS), or the capacity for landscapes to provide equitable access to ecosystem services essential for human wellbeing for both current and future generations, provides an operational approach to monitor these transitions. However, the complexity of landscapes complicates how and what to consider when assessing LS.

Intermittent Sinus Pause/Asystole in the Setting of Anticholinergic Overdose.

Anticholinergic toxicity typically presents with symptoms of cutaneous vasodilation, delirium, mydriasis, urinary retention, hyperthermia, anhidrosis, and tachycardia. This case report presents a 68-year-old female patient who exhibited some of these signs and symptoms after ingesting an unknown quantity of dicyclomine. However, she displayed one notable exception to the classic toxidrome.

Patient Perspectives on Home Tonometer Usage for Glaucoma.

Purpose: To understand patient experiences using the iCare HOME tonometer through assessing ease of use, device usage patterns, proficiency, and patient comments.

Methods: We conducted a prospective survey-based cohort study of 19 patients (35 eyes) with glaucoma or glaucoma suspect diagnoses. Patients received training on home tonometer usage and were loaned the device for one week to measure intraocular pressure at home multiple times daily.

Perception of without infection induces in .

pathogenic susceptibility is influenced by the worm's detection of its environment and its capacity to resist and resolve damage following infection. Here, we use a model where worms can sense, but not ingest, the pathogen (EF) We identify that perception of EF without infection induces the stress-response gene further identify that neural and intestinal signaling genes are necessary for induction without active infection. Finally, we show that overexpression is sufficient to extend lifespan with EF exposure, while KO is not detrimental, suggesting that additional expression benefits worms in this condition.

Cocaine-induced Vasculitis: Uncommon Manifestations in the Lower Extremities - A Case Report.

Levamisole-induced vasculitis is a recognized dermatopathologic phenomenon frequently observed in individuals engaged in illicit substance use, particularly cocaine. Levimasole's structural resemblance to cocaine leads to its utilization as a cutting or bulking agent, creating an illusion of unaltered purity. While this vasculitis typically manifests in cartilaginous areas such as the ears and nose, it can also occur, though less commonly, in the lower extremities.

Unveiling Lyme Neuroborreliosis in the Absence of Dermatological Symptoms.

Lyme neuroborreliosis can present with isolated neurological manifestations, posing diagnostic challenges, especially in the absence of hallmark dermatological symptoms like erythema migrans. This case highlights a patient with isolated cervical radiculopathy due to Lyme neuroborreliosis, presenting without systemic features such as fever, arthralgia, or rash. The diagnosis was confirmed through serological testing, with positive findings on the Western blot.

Evaluation of Thigh Muscle Strength in Adolescent Patients After Anterior Cruciate Ligament Reconstruction With Lateral Extra-articular Tenodesis or Anterolateral Ligament Reconstruction.

Background: There has been increased interest in lateral extra-articular procedures, such as anterolateral ligament reconstruction (ALLR) or lateral extra-articular tenodesis (LET), to reduce anterolateral rotation instability of the knee after anterior cruciate ligament reconstruction (ACLR). Despite promising surgical outcomes with these techniques, their impact on knee strength recovery is unknown.

Hypothesis: Patients undergoing lateral extra-articular procedures at the time of ACLR would have impaired thigh muscle strength at 6 to 9 months after surgery.

Immortalization of epidural fat-derived mesenchymal stem cells: characterization and adipocyte differentiation potential.

Background: Mesenchymal stem cells (MSCs) are promising candidates for regenerative therapy due to their self-renewal capability, multilineage differentiation potential, and immunomodulatory effects. The molecular characteristics of MSCs are influenced by their location. Recently, epidural fat (EF) and EF-derived MSCs (EF-MSCs) have garnered attention due to their potential benefits to the spinal microenvironment and their high expression of neural SC markers.

Broadband internet access as a social determinant of health in the early COVID-19 pandemic in U.S. counties.

Recent work suggests that internet access was key in delivering life-saving health information about the COVID-19 pandemic. This paper expands on these findings by focusing on the early pandemic in the United States to examine the role of internet access on masking and COVID-19 incidence and mortality. Using county-level data from the American Community Survey, The New York Times, and other sources, weighted OLS regression models with state fixed-effects were used to predict the association of internet access on self-reported masking in July 2020 and COVID-19 incidence and mortality during multiple periods from July-October 2020.

Neuroevolution gives rise to more focused information transfer compared to backpropagation in recurrent neural networks.

Artificial neural networks (ANNs) are one of the most promising tools in the quest to develop general artificial intelligence. Their design was inspired by how neurons in natural brains connect and process, the only other substrate to harbor intelligence. Compared to biological brains that are sparsely connected and that form sparsely distributed representations, ANNs instead process information by connecting all nodes of one layer to all nodes of the next.

Neighborhood Socioeconomic Disadvantage and Physical Disorder, Parenting Strategies, and Youths' Future Orientation.

Neighborhood disadvantage has been linked to youths' diminished future orientation, defined as the degree to which one thinks about, anticipates, and plans for the future. Yet, parenting behaviors may moderate this link. Using longitudinal data from parent-child dyads ( = 101, 51.

The anomalous state of Uranus's magnetosphere during the Voyager 2 flyby.

The Voyager 2 flyby of Uranus in 1986 revealed an unusually oblique and off-centred magnetic field. This single in situ measurement has been the basis of our interpretation of Uranus's magnetosphere as the canonical extreme magnetosphere of the solar system; with inexplicably intense electron radiation belts and a severely plasma-depleted magnetosphere. However, the role of external forcing by the solar wind has rarely been considered in explaining these observations.

A 5-year single-center review of seropositivity in kidney transplant candidates in Central Texas.

Introduction: is a soil-transmitted helminth that can lead to life-threatening hyperinfection in transplant recipients. Targeted screening based on social history alone may preclude a large proportion of seropositive patients. Our institution implemented universal screening for kidney transplant candidates.

Resident Experiences at a Community Hospital Caring for Patients Who Are Incarcerated.

There is no standardized curriculum that teaches medical residents to navigate the ethical and logistical complexities of bedside care delivery to patients who are incarcerated. In this article, we describe resident physician bedside experiences at a community teaching hospital caring for patients who are incarcerated. From 2022 to 2023, residents in emergency medicine, general surgery, internal medicine, and obstetrics and gynecology were offered an anonymous survey, self-administered via REDCap software, to explore their experiences caring for this patient population.

Not all who meander are lost: migrating sea lamprey follow river thalwegs to facilitate safe and efficient passage upstream.

Efficient navigation is crucial for the reproductive success of many migratory species, often driven by competing pressures to conserve energy and reduce predation risk. Little is known about how non-homing species achieve this balance. We show that sea lamprey (Petromyzon marinus), an ancient extant vertebrate, uses persistent patterns in hydro-geomorphology to quickly and efficiently navigate through complex ecosystems.

Facilitators of antibiotic decision-making in home-based primary care: a qualitative investigation.

Interviews with 22 home-based primary care (HBPC) clinicians revealed that infectious disease physicians and clinical pharmacists facilitate infection management and antibiotic selection, respectively, and that local initiatives within programs support antibiotic prescribing decisions. Interventions that facilitate specialist engagement and tailored approaches that address the unique challenges of HBPC are needed.

Criminal Offending and Incarceration in United States Adults With Early Phase Psychosis and Comorbid Substance Use Disorder.

Aim: Studies have shown that people experiencing early phase psychosis (EPP) are at increased risk for criminal conviction and incarceration. However, there is limited data looking at overall legal burden. To address these gaps in the literature, the goal of this study was to categorise criminal charges and convictions using the United States Federal Bureau of Investigation (FBI) uniform crime reporting (UCR) program, assess frequency of incarcerations, and describe the frequency of substance use disorder (SUD) diagnoses and its relationship to criminal offending and incarceration in a well categorised EPP population.

Inpatient Audiograms: A Mixed Methods Study Examining Clinical Decision Making, Financial Analyses, and Audiologist Perspectives.

Objective: Evaluate inpatient audiometry on clinical decision-making. Assess stakeholder perspectives on the practice of inpatient audiometry and financial impact.

Study Design: This is a mixed methods study utilizing retrospective chart review, a focus group, and financial analyses.

Ultrasound-Based Local Lung Motion Assessment Using Synthetic Lateral Phase.

Background: Ultrasound lung surface motion measurement is valuable for the evaluation of a variety of diseases. Speckle tracking or Doppler-based techniques are limited by the loss of visualization as a tracked point moves under ribs or is dependent.

Methods: We developed a synthetic lateral phase-based algorithm for tracking lung motion to overcome these limitations.