Numerical modeling of the funnel multiphysical flow of fresh self-compacting concrete considering proportionate heterogeneity of aggregates.

Filling ability is one of the prominent rheological properties of the self-compacting concrete (SCC), which has been studied in this research work deploying the functional behavior of the concrete through the studied funnel apparatus using the coupled ANSYS-SPH interface. Seven (7) model cases were studied and optimized. The aim of this numerical study is to propose a more sustainable mix of coarse and fine aggregates proportion that allows for most minimum flow time to enhance a more efficient filling of forms during concreting.

Understanding apoptosis in sickle cell anemia patients: Mechanisms and implications.

Sickle cell anemia (SCA) is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, leading to the formation of sickle-shaped red blood cells. While much research has focused on the molecular and cellular mechanisms underlying the pathophysiology of SCA, recent attention has turned to the role of apoptosis, or programmed cell death, in the disease progression. This review aims to elucidate the intricate mechanisms of apoptosis in SCA patients and explore its implications in disease severity, complications, and potential therapeutic interventions.

Effects of aggregate sizes on the performance of laterized concrete.

Due to the high costs of traditional concrete materials in Nigeria, such as river sand, there is an increasing demand to explore alternative materials like laterite for fine aggregates. Although laterite is abundant in Nigeria, its full potential in the construction industry remains untapped. Previous studies have shown that partially replacing river sand with laterite produces concrete with competitive strength properties.

Soil Enzymes and Antioxidants Activities of Edible Vegetables Grown in Soils Polluted by Gas Flaring.

Associated gas flaring has several consequences on the environment. This study was aimed at assessing the impact of gas flaring on soil enzymes and plant antioxidant activities from gas flare-bearing communities in Nigeria. Soil and plant samples were obtained from farmlands in Ukwa West and Izombe gas flaring sites, as well as unpolluted site from Olokoro (used as control).

Phytochemical profiling, toxicity studies, wound healing, analgesic and anti-inflammatory activities of Musa paradisiaca L. Musaceae (Plantain) stem extract in rats.

Ethnopharmacological Relevance: The stem of Musa paradisiaca (plantain) has found application in traditional medicine for the treatment of diabetes, inflammation, ulcers and wound injuries.

Aim Of The Study: This study investigated the phytochemical composition, toxicity profile, wound healing, anti-inflammatory and analgesic effects of aqueous Musa paradisiaca stem extract (AMPSE) in rats.

Methods: Phytochemical analysis of methanol-MPSE was performed by gas chromatography-mass spectrometry (GC-MS).

A study on waste PCB fibres reinforced concrete with and without silica fume made from electronic waste.

This research goal is to appraise the effect of electronic waste on concrete properties by examining the mechanical properties of concrete reinforced with waste printed circuit boards (PCBs). PCB fibres, each 50 mm long, were mixed in varying proportions (1-5% by weight of cement). Silica fume (SF) was used as a 12% weight replacement for cement to conserve the properties of PCB fibre-reinforced concrete while tumbling cement consumption.

The methanolic extract of downregulates the relative expression of 1 gene in the hypothalamus of Wistar rats: A preliminary report.

Objective: 1 gene expression in the rat hypothalamus was investigated following administration of methanolic extract of (MEHS) to provide mechanistic evidence for the reproductive effect of the MEHS as a potential regulator of 1 gene (which directly controls the hypogonadal axis).

Materials And Methods: This experiment was done using fifteen (15) male rats with average weight of 148 g, randomly grouped into three (3) groups (A-C). Group A was the control group and received no treatment.

Some developments on seasonal INAR processes with application to influenza data.

Influenza epidemic data are seasonal in nature. Zero-inflation, zero-deflation, overdispersion, and underdispersion are frequently seen in such number of cases of disease (count) data. To explain these counts' features, this paper introduces a flexible model for nonnegative integer-valued time series with a seasonal autoregressive structure.

Translation of HIV/AIDS knowledge into behavior change among secondary school adolescents in Uganda: A review.

The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pandemic is primarily affecting young people worldwide, with those between the ages of 15 and 24 accounting for nearly half of all new infections. This paper was written to effectively translate HIV/AIDS knowledge into actionable behavioral changes among secondary school students in Uganda by empowering them with comprehensive information, fostering a deeper understanding of preventive measures, and facilitating the development of responsible and informed decision-making skills, thereby reducing the incidence of HIV/AIDS transmission within this demographic. There is a relationship between risk perception and behavior change in HIV/AIDS prevention among high school students.

Analysis of the antibacterial effects of turmeric on particular bacteria.

Antimicrobial properties of plants have been investigated by a number of studies worldwide and many of them have been used as therapeutic alternatives because of their antimicrobial properties. The quest for suitable and affordable alternative in the face of increasing antimicrobial drug resistant has led researchers into exploring the use of plant extract in the treatment of infections. The antibacterial properties of turmeric (Curcuma longa) on selected bacteria were evaluated.

A critical review of rheological models in self-compacting concrete for sustainable structures.

Studying the rheological behavior of concrete, especially self-compacting concrete is vital in the design and structural integrity of concrete structures for design, construction, and structural material sustainability. Both analytical and numerical techniques have been applied in the previous research works to study precisely the behavior of the yield stress and plastic viscosity of the fresh self-compacting concrete with the associated flow properties and these results have not been systematically presented in a critical review, which will allow researchers, designers and filed operators the opportunity to be technically guided in their design and model techniques selection in order to achieve a more sustainable concrete model for sustainable concrete buildings. Also, the reported analytical and numerical techniques have played down on the effect of the shear strain rate behavior and as to reveal the viscosity changes of the Bingham material with respect to the strain rate.

Impact of germination on the techno-functional properties, nutritional composition, and health-promoting compounds of brown rice and its products: A review.

Rice is a popular grain and forms part of the daily diet of people throughout the world. However, the consumption of rice and its products is sometimes limited by its high glycemic index due to its high starch content, low protein content and quality, and low bioavailability of minerals due to the presence of anti-nutritional factors. This has partly stimulated research interest in recent times toward the use of bioprocessing techniques such as germination as cheap and natural means to improve the nutritional quality, digestibility, and health properties of cereals, including rice, to partially achieve nutrition and food security in the developing regions of the world.

Finnish diabetes risk score outperformed triglyceride-glucose index in diabetes risk prediction.

Purpose: Triglyceride-Glucose (TyG) index is a surrogate marker of insulin resistance. This study compared the performance of TyG index and the Finnish diabetes risk score (FINDRISC) in diabetes risk prediction.

Methods: This cross-sectional study involved 122 young adults (aged 15-35 years) in Asaba, Delta State, Nigeria.

Characterization of net-zero pozzolanic potential of thermally-derived metakaolin samples for sustainable carbon neutrality construction.

Metakaolin (MK) is one of the most sustainable cementitious construction materials, which is derived through a direct heating procedure known as calcination. Calcination process takes place substantially lower temperatures than that required for Portland cement, making it a more environmentally sustainable alternative to traditional cement. This procedure causes the removal of hydroxyl water from the naturally occurring kaolin clay (AlSiO(OH) with MK (AlO·2SiO) as its product.

Experimental investigation and modelling of the mechanical properties of palm oil fuel ash concrete using Scheffe's method.

This study explores the enhancement of mechanical properties in concrete blended with palm oil fuel ash (POFA) through Scheffe's optimization. The utilization of POFA as supplementary cementitious material in concrete has gained attention for its potential environmental benefits. Utilizing a (5,2) simplex-lattice design, a systematic approach is employed for optimizing mixture proportions based on response parameters.

Attentive transformer deep learning algorithm for intrusion detection on IoT systems using automatic Xplainable feature selection.

Recent years have witnessed an in-depth proliferation of the Internet of Things (IoT) and Industrial Internet of Things (IIoT) systems linked to Industry 4.0 technology. The increasing rate of IoT device usage is associated with rising security risks resulting from malicious network flows during data exchange between the connected devices.

Desmoglein-2 and COVID-19 complications: insights into its role as a biomarker, pathogenesis and clinical implications.

Desmoglein-2 (DSG2) has emerged as a potential biomarker for coronavirus disease 2019 (COVID-19) complications, particularly cardiac and cardiovascular involvement. The expression of DSG2 in lung tissues has been detected at elevated levels, and circulating DSG2 levels correlate with COVID-19 severity. DSG2 may contribute to myocardial injury, cardiac dysfunction and vascular endothelial dysfunction in COVID-19.

Recycling and sustainable applications of waste printed circuit board in concrete application and validation using response surface methodology.

The present investigation aims to examine the mechanical and durability properties of concrete that has been reinforced with a waste printed circuit board (WPCB) towards a low-carbon built environment. It assessed the fresh and hardened characteristics of the low-carbon concrete reinforced with WPCB fibres, after a curing period of 7 and 28 days. The evaluation was done by quantifying slump, compressive strength, split tensile strength, flexural strength, sorptivity, rapid, and acid tests.

Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats.

Ethnopharmacological Relevance: Ananas comosus (pineapple) leaf is used in ethnomedicine to treat diarrhoea, inflammation, pain, bacterial infections and oedema.

Aim Of The Study: The aim of this study was to investigate the anti-diarrhoeal, anti-inflammatory and analgesic effects as well as the toxicity profile of the aqueous Ananas comosus leaf extract (AACLE) in rats.

Methods: Methanol ACLE was subjected to gas chromatography-mass spectrometry (GC-MS) analysis.

Phytochemical composition, toxicological profiling and effect on pup birth weight of Corchorus olitorius leaf extract in rats: Implications for fetal macrosomia control.

Ethnopharmacological Relevance: Corchorus olitorius is used in ethnomedicine to arrest threatened miscarriage, ease labour, and promote smooth childbirth.

Aim Of The Study: To evaluate the phytochemical composition, toxicity profile, and effect of Corchorus olitorius L. leaf extract (COLE) on fetal macrosomia control in rats.

Soft computing techniques for predicting the properties of raw rice husk concrete bricks using regression-based machine learning approaches.

In this study, the replacement of raw rice husk, fly ash, and hydrated lime for fine aggregate and cement was evaluated in making raw rice husk-concrete brick. This study optimizes compressive strength, water absorption, and dry density of concrete brick containing recycled aggregates via Response Surface Methodology. The optimized model's accuracy is validated through Artificial Neural Network and Multiple Linear Regression.

Can location factors moderate the effects of the demographic composition of SME's owner managers on the rate of mobile marketing technology (MMT) adoption?

Extant scholarly inquiries focused predominantly on the influence of demographic physiognomies of SMEs' owner-managers on MMT adoption, with dearth recourse to how the proxies of location factors such as workforce diversity and knowledge centres moderate and describe such relationship. To bridge that void, opinions of 345 SMEs' owner-managers in five industries situated in the state capital and commercial nerve cities of three Geo-political zones of Nigeria were purposively sampled. The analysis involved hierarchical regression and its outcome showed that diversified workforce and enhanced knowledge centres critically moderated the extant relationship between the demographic composition (age, gender, education and experience) of owner-managers and MMT adoption.

University female students' perception and prospective practice of female genital mutilation in Umudike, Southeast Nigeria.

Female genital mutilation (FGM) under the guise of female circumcision is still practiced across wider communities in Nigeria despite various dangers associated with it and several efforts to curtail the practice. This study investigated the prevalence of and personal disposition towards female genital mutilation in 345 university undergraduate students of Michael Okpara University of Agriculture, Umudike (MOUAU), South east Nigeria using a pre-tested structured questionnaire. The major inclusion criteria for the face-to-face interview were being a female student of MOUAU and consented approval.

Comparative pathogenicity of single and mixed drug-resistant Trypanosoma brucei brucei and Trypanosoma congolense infections in rats.

Drug-resistant trypanosomes are widespread in sub-Saharan Africa and in conjunction with the drug-sensitive phenotypes cause a serious endemic wasting disease in animals. We evaluated the pathogenicity of single and mixed drug-resistant Trypanosoma brucei brucei and T. congolense isolates in 35 female rats, randomly divided into seven groups (1-7) of five rats.

Nutritional and physicochemical changes in two varieties of fonio ( and ) during germination.

Germination is a cheap and effective bioprocessing technique used for improvement of the nutritional, physicochemical and health-promoting properties of seeds. The benefits of germination on two fonio varieties ( and ) have not been studied. This study investigated the nutritional and physicochemical changes in two varieties of fonio germinated for 24, 48 and 72 h at 28 °C.