Redefining Neonatal Vitamin A Adequacy and Deficiency Based on Maternal Nutrition: A Cross-Sectional Study in Chongqing, China.

There are no established diagnostic criteria for neonatal vitamin A deficiency (VAD), and applying adult VAD criteria to neonates may overestimate the neonatal VAD rate. This study aimed to evaluate neonatal vitamin A (VA) status and redefine thresholds for neonatal VA adequacy and deficiency based on maternal VA nutrition. A cross-sectional study involving 1901 mother-neonate pairs was conducted in Chongqing, China.

Primary Extraosseous Ewing Sarcoma on 18 F-FDG and 68 Ga-FAPI-04 PET/CT.

Primary extraosseous Ewing sarcoma of the nasal cavity is rare. A 17-year-old man underwent 18 F-FDG and 68 Ga-FAPI-04 PET/CT for a nasal mass. The mass showed avid FDG uptake but weak FAPI uptake.

A high-resolution 3D radiochromic hydrogel photonic crystal dosimeter for clinical radiotherapy.

The precise, rapid and direct visualization of 3D topographical dose in the target tissue that is crucial for effective radiation therapy remains a challenge. Herein, by combining hydrogel photonic crystals with film stacking or 3D printing, a 3D radiochromic dosimeter with a dose sensitivity of up to 10 nm Gy, a spatial resolution <50 μm, and the ability to detect complex 3D topographical dose distribution was proposed for clinical radiation dose verification. The sensitivity and response range of the dosimeter by radiation-induced polymer cross-linking and consequent Bragg wavelength shift can be tuned the solid content and extent of acrylate modification.

Relationship between intracranial pressure and neurocognitive function among older adults after radical resection of rectal cancer.

Background: Older patients are prone to postoperative cognitive decline after laparoscopic rectal cancer surgery, which may be associated with increased intraoperative intracranial pressure (ICP). This study investigated the correlation between intraoperative ICP changes, as indicated by measurements of the optic nerve sheath diameter (ONSD) using ultrasonography, and subsequent cognitive function to provide better patient care.

Aim: To evaluate changes in ICP and associated postoperative neurocognition in older adults after laparoscopic radical resection for rectal cancer.

CTP-Derived venous outflow profiles correlate with tissue-level collaterals regardless of arterial collateral status.

Background And Purpose: Tissue-level collaterals (TLC), which quantify the state of arterial blood flow transiting through cerebral ischemic tissue, have been shown to be related to the clinical outcomes of acute ischemic stroke (AIS), regardless of the arterial collateral status on computed tomography angiography(CTA). Herein, we investigated whether venous outflow (VO) profiles on computed tomographic perfusion (CTP) were linked to TLC, regardless of the arterial collateral status.

Methods: Consecutive anterior circulation AIS patients with large vessel occlusion(LVO) undergoing thrombectomy in a retrospective cohort were evaluated between January 2021 and August 2023 at two comprehensive stroke centers.

Cognitive frailty as a predictor of hospitalisation among older adults: a systematic review and meta-analysis.

To examine whether cognitive frailty serves as a predictor of hospitalisation in older adults. PubMed, Web of Science, Embase, Scopus and Cochrane Library databases were systematically searched from inception to February 6, 2024. The reviewers independently selected studies, extracted data and evaluated the quality of studies.

Successful sequential management of traumatic choledochal leak and stenosis in children using ERCP: a case report and literature review.

Traumatic Choledochal Leak and Stenosis in Children is a relatively rare bile leakage, and there is no report of endoscopic retrograde cholangiopancreatography [ERCP] bile duct stent treatment in 3 years old, which avoids procedure and biliary tract modifications after the failure of conservative treatment of bile leakage, and solves the previous need for procedure in a minimally invasive or even non-invasive way. At the same time, it can be concluded that identifying the signs of conservative treatment failure is important, and ERCP is superior to CT and MR in diagnosing traumatic biliary leak in young children. Traumatic bile leakage common bile duct inflammatory stenosis, brittle tissue, not suitable for expansion, the choice of 5 Fr to 10 Fr plastic stent sequential treatment is an effective regimen.

Modified screw-rod fixation for management of posterior pelvic ring fractures: a retrospective study.

Background: Pelvic fractures are often associated with life-threatening damage and mechanical instability. Surgical therapy is a prior choice. To minimize surgical invasion and risk, bilateral screws combined with curved rod were applied to stabilize posterior pelvic ring.

Central retinal artery occlusion following surgery for thyroid eye disease: A case report.

Rationale: Thyroid eye disease (TED) is the most common orbital disorder in adults and significantly affects patient health. Orbital decompression surgery is an important treatment option. Central retinal artery occlusion (CRAO) after orbital medial wall decompression is rare in patients with TED.

Instruments for Measuring the Burden of Family Caregivers of Cancer Patients: A Systematic Review of Measurement Properties.

Aims: This study identifies instruments for assessing the burden on family caregivers of cancer patients and evaluates their psychometric properties using COSMIN criteria.

Design: A systematic review based on COSMIN methodology.

Methods: The review adhered to PRISMA guidelines.

Recurrence and postoperative quality of life after surgical resection of unilateral cT1-T3N1bM0 papillary thyroid carcinoma.

Background: Determining the optimal extent of surgery and improving postoperative quality of life for patients with papillary thyroid cancer has been an important challenge. Here, we evaluated postoperative quality of life after cT1-T3N1bM0 papillary thyroid carcinoma (PTC) to explore the optimal scope of surgical resection.

Methods: In this study, we investigated surgical outcomes in patients diagnosed with unilateral cT1-T3N1bM0 PTC, who were treated at Harbin Medical University Cancer Hospital from January 2008 to December 2018.

pH-Dependent Assembly and Stability of Toll-Like Receptor 3/dsRNA Signaling Complex: Insights from Constant pH Molecular Dynamics and Metadynamics Simulations.

The pH-dependent assembly of Toll-like receptors (TLRs), which triggers a threshold-like response, is a key principle in immune signaling. While crystallography has revealed the intricate structure of these assembly complexes, the mechanisms underlying their pH dependency remain unclear. Herein, constant pH simulations and metadynamics are employed to investigate the pH-dependent assembly and stability of the TLR3/dsRNA signaling complex.

Belimumab safety in adult and paediatric Chinese patients with systemic lupus erythematosus: A Phase 4, multicentre, observational study.

Objective: Although belimumab has been widely used in patients with systemic lupus erythematosus (SLE) globally, real-world safety data among Chinese patients are limited, particularly for children. This study assessed the safety and tolerability of belimumab in adult and paediatric patients with SLE in China in real-world clinical practice.

Methods: This Phase 4, multicentre, prospective, observational study enrolled patients prescribed intravenous belimumab by their physicians in tertiary hospitals, independent of a clinical study, during routine clinical visits between May 2021 and May 2022.

Sustained Protraction Increases Lengthening of the Mandibular Condylar Process Whilst Changes Its Growth Direction in a Rat Model.

Objective: In Class II elastics treatment, the mandible is subject to sustained protraction. The study aimed to investigate the morphological and histological changes resulting from sustained mandibular protraction, through establishment of a novel model in rat.

Materials And Methods: Forty-eight 4-week-old male Sprague-Dawley rats were randomly divided into three groups, including the 50 and 100 cN protraction groups, and the control.

Infantile bacterial meningitis combined with sepsis caused by : A case report.

Background: (SGSP) is a rare pathogen responsible for infant sepsis and meningitis and is potentially overlooked because it is not included in routine group B streptococcal screenings. Hence, we present a case of SGSP-induced infant meningitis and sepsis, accompanied by bronchopneumonia induced by multidrug-resistant (MRSA), providing insights into the identification, management, and prognosis of this bacterial infection.

Case Summary: A 45-day-old female infant presented with two episodes of high fever (maximum temperature: 39.

Managements for perioperative anxiety in patients with gastrointestinal cancers.

Gastrointestinal (GI) cancers are the most common malignancies, while surgical intervention remains the sole therapeutic approach offering the possibility of a definite cure for cancer. Perioperative anxiety negatively impacts the recovery of GI cancers. Recently, mounting studies have demonstrated that proper nursing interventions may alleviative perioperative anxious illnesses in patients with GI cancers.

Efficacy and safety of anlotinib combined with S‑1 as a third‑ or later‑line treatment for advanced non‑small cell lung cancer in China: A systematic review and meta‑analysis.

Anlotinib is presently used as a third-line treatment for non-small cell lung cancer. However, it is not yet reported whether combining anlotinib with S-1 as a third- or later-line treatment offers superior outcomes compared with anlotinib alone. The present meta-analysis aimed to address this question by systematically searching the PubMed, Embase, Web of Science, Cochrane Library, CMB and China National Knowledge Infrastructure databases for eligible studies published from the establishment of the database to January 10, 2024.