1,471 results match your criteria: "Miami Hand & Upper Extremity Institute[Affiliation]"

Article Synopsis
  • - HIV-associated neurocognitive disorder (HAND) and Alzheimer's disease (AD) share similar clinical symptoms and underlying mechanisms, complicating their distinction, especially after the introduction of antiretroviral therapy (ART), which has changed how HAND presents.
  • - The concept of Alzheimer's disease-like dementia (ADLD) in those with HIV highlights this overlap, with potential mechanisms involving epigenetic changes, persistent low viral load, inflammation, and factors linked to traditional AD risk.
  • - Research suggests that HIV-specific microRNAs in extracellular vesicles could be crucial in understanding and treating ADLD, making it valuable to study the effects of HIV-positive extracellular vesicles on Alzheimer's model mice to identify these microRNAs.
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Keratoacanthoma versus Squamous-Cell Carcinoma: Histopathological Features and Molecular Markers.

Dermatopathology (Basel)

October 2024

Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.

Article Synopsis
  • There is significant debate in dermatopathology about how to distinguish keratoacanthoma (KA), a benign tumor, from squamous-cell carcinoma (SCC), which is dangerous and requires treatment.
  • Some experts argue KAs are self-limiting and don't need intervention, while others stress the importance of early diagnosis and treatment of SCC to prevent severe outcomes.
  • Ongoing research is exploring genetic and molecular differences to improve understanding and diagnostic techniques for both conditions.
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Background: Although several surveys of infection prevention and control (IPC) practices have been conducted in the United States, none have focused on the state of Florida, which has the fourth-largest number of certified nursing facilities in the country. A needs assessment survey was conducted to better understand the specific needs and practices of individuals responsible for IPC in long-term care facilities (LTCFs) in Florida.

Methods: In November and December of 2022, a 90-question online survey was distributed to individuals responsible for IPC activities at 3,690 LTCFs in Florida.

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Safety of Kidney Transplantation from Donors with HIV.

N Engl J Med

October 2024

From the Departments of Medicine (C.M.D., T.L., D.B., D.O., Y.E., F.N., A.D.R.), Surgery (N.D.), and Pathology (S.B., A.A.R.T.), Johns Hopkins University School of Medicine, Baltimore, the Department of Medicine, University of Maryland School of Medicine (J.B.), and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda (N.W., E.B., J.O., A.D.R.) - all in Maryland; the Department of Population Health, New York University (NYU) Grossman School of Medicine (A.M., D.L.S.), the Recanati-Miller Transplantation Institute, Mount Sinai Hospital (S.F.), the Department of Medicine, Icahn School of Medicine at Mount Sinai (M.M.R.), NYU Langone Transplant Institute (S.A.M., D.L.S.), the Department of Medicine, Columbia University Irving Medical Center (M.R.P.), and the Department of Medicine, Weill Cornell Medicine (C.B.S.) - all in New York; the Department of Medicine, Emory University, Atlanta (R.F.-M.); the Department of Medicine, Georgetown University, Washington, DC (A.G.); the Department of Surgery, University of California, San Francisco, San Francisco (P.S.), the Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla (S. Aslam), and the Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles (J.S.) - all in California; the Section of Transplant Nephrology, University of Alabama at Birmingham, Birmingham (S.M.); the Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine (V.S.), and the Division of Infectious Diseases, Rush University Medical Center (C.A.Q.S.) - both in Chicago; the Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami (M.I.M.); the Department of Medicine, Ochsner Health, New Orleans (J.H.); the Section of Infectious Diseases, Yale School of Medicine, New Haven, CT (M.M.); the Department of Medicine, University of Pittsburgh, Pittsburgh (G.H.), and the Department of Medicine, Perelman School of Medicine at the University of Pennsylvania (E.A.B.), and the Department of Medicine, Drexel University College of Medicine (K.R.), Philadelphia - all in Pennsylvania; the Department of Medicine, University of Texas Southwestern Medical Center (D.W.), and the Department of Medicine, Methodist Health System Clinical Research Institute (J.A.C.-L.) - both in Dallas; the Department of Medicine, Indiana University Health, Indianapolis (O.A.); the Department of Surgery, Massachusetts General Hospital, Boston (N.E.); the Department of Surgery, University of Arkansas for Medical Sciences, Little Rock (E.G.); and the Department of Medicine, University of Cincinnati College of Medicine, Cincinnati (S. Apewokin).

Article Synopsis
  • Kidney transplantation from HIV-positive donors to HIV-positive recipients is a growing practice, initiated under a 2016 U.S. law, and is currently being evaluated for broader clinical implementation.
  • An observational study involving 408 candidates at 26 U.S. centers assessed the safety and health outcomes of kidney transplants from both HIV-positive and HIV-negative donors to HIV-positive recipients, finding no significant difference in major health risks between the two donor groups.
  • Results indicated similar long-term survival rates, graft success, and complication rates across both groups, although recipients of kidneys from HIV-positive donors showed a higher incidence of HIV breakthrough infections.
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Dilated cardiomyopathy (DCM) is a heart condition that causes enlarged and weakened left ventricles and affects the heart's ability to pump blood effectively. Most genetic etiology still needs to be understood. Previously, we have used the known germline hereditary fusion genes (HFGs) to identify HFGs associated with multiple myeloma and leukemia.

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People with significant health anxiety may experience brain-gut dysregulation, leading to increased visceral sensitivity and greater gastrointestinal (GI) symptoms. Positive affect (PA), on the other hand, may serve as a protective characteristic, buffering the negative impact of health anxiety on GI symptoms. This study investigated interrelationships between health anxiety, PA, and GI symptoms.

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Article Synopsis
  • Medication adherence is a significant issue, with over 50% of US adults not following their prescribed medication regimens, mainly because they manage their medications at home.
  • A study of 1,673 survey respondents revealed common medication storage locations, with nightstands and kitchen cabinets linked to forgetfulness in taking medication, while certain locations like desks and dining tables were associated with better adherence.
  • Most respondents (96%) expressed willingness to receive advice from healthcare providers on medication storage, highlighting the potential for tailored interventions to improve adherence through personalized guidance.
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Background: Traumatic digit amputation is a common injury with life-altering consequences for thousands of patients each year. In this study, we aim to update and expand the reported outcomes of return-to-work (RTW) and functional recovery in patients treated with digit replant after traumatic amputation.

Methods: A PRISMA-guided systematic review was performed to identify all published articles related to digit replantation following amputation.

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Article Synopsis
  • The study explores the distribution of small non-coding RNAs (sncRNAs) like isomiRs, tRNA-derived fragments (tRFs), and rRNA-derived fragments (rRFs) in cancer cells, challenging previous assumptions about their uniform distribution.
  • Using advanced mathematical modeling to analyze samples from three cell lines, researchers found that the subcellular locations of these sncRNAs vary significantly based on their sequences and the specific cell type.
  • These findings suggest that even slight differences in the sequences of the same sncRNA can influence its function and distribution, highlighting the need for more detailed studies to fully understand their roles in cancer.
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Bipolar latissimus dorsi transfer has been considered a viable option for the restoration of elbow flexion in patients with large traumatic defects of the anterior arm compartment. Advantages of bipolar transfer of the latissimus include stabilization of the anterior shoulder joint in addition to recreating the biceps for a direct line of pull in restoring elbow flexion with minimal donor site morbidity. Previous literature in bipolar latissimus transfer has demonstrated good outcomes in elbow flexion against gravity, range of motion, and patient satisfaction.

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Introduction: Dr. Asa G. Yancey published a surgical technique describing a pull - through of normal colon through a cuff of aganglionic colon to treat Hirschsprung disease in 1952, 12 y before Dr.

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Article Synopsis
  • The study investigates the experiences of Haitians/Haitian Americans in Miami-Dade County during the COVID-19 pandemic, focusing on their views and practices around vaccination.
  • Researchers conducted qualitative interviews with 15 community members and 15 stakeholders, identifying nine key themes related to the pandemic's impact on health, employment, and personal relationships.
  • The findings highlight the significant challenges faced by this community, suggesting a need for targeted interventions and collaboration between health agencies and community partners to improve trust and vaccine acceptance.
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Article Synopsis
  • In a study on palmoplantar psoriasis, risankizumab (RZB) was evaluated against a placebo (PBO) for 16 weeks, followed by an extension to week 52.
  • The results showed that RZB significantly outperformed PBO in achieving clear or nearly clear skin, with various response measures showing marked improvement at week 16.
  • RZB was found to be well-tolerated, with no new safety issues arising throughout the study, though it was noted that there was no comparison with other biologic treatments.
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Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with rising prevalence, necessitating early diagnosis and intervention. This case report examines the clinical diagnosis approach of ASD in children under two years, emphasizing motor developmental delay, chromosome 19 mutations, prematurity, macrocephaly, and false-negative Modified Checklist for Autism in Toddlers (MCHAT) results. This study identifies gross motor delays as a potential key indicator in the diagnosis of ASD, as all five cases (Patients A, B, C, D, and E) were observed to have such deficits.

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Background:  Targeted muscle reinnervation (TMR) is an effective surgical treatment of neuropathic pain for amputees. However, limited data exist regarding the early postoperative pain course for patients who undergo either primary (<14 days since amputation) or secondary (≥14 days) TMR. This study aims to outline the postoperative pain course for primary and secondary TMR during the first 6 postoperative months to aid in patient education and expectation management.

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Combined Median, Ulnar, and Radial Nerve Injury after a Spiral Humeral Shaft Fracture.

Plast Reconstr Surg Glob Open

August 2024

From the Division of Plastic Surgery, Department of Surgery, University of Miami, Miami, Fla.

We report the case of a 43-year-old woman who presented with combined radial, median, and ulnar nerve palsies and a spiral humeral shaft fracture after falling down stairs. Postinjury, the patient did not recover full median, ulnar, and radial nerve function despite aggressive hand therapy. Electrodiagnostic studies and imaging findings were concerning for traction neuropraxia or transection, radial nerve neuroma, and scar encasement of the radial, median, and ulnar nerves.

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Prior studies found hand preference trajectories predict preschool language outcomes. However, this approach has been limited to examining bimanual manipulation in toddlers. It is not known whether hand preference during infancy for acquiring objects (i.

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Pediatric Hand Surgery Training: A Spectrum of Educational Resources.

J Hand Surg Glob Online

July 2024

Pediatric Hand Surgery, Division of Pediatric Plastic and Hand Surgery, Valley Children's Healthcare, Madera, CA.

Treatment of children with upper-extremity trauma, congenital hand differences, cerebral palsy, and brachial plexus birth injuries requires specialized training, given the spectrum of pathology and complexities of treating an individual who is still developing. Although a limited number of dedicated pediatric hand surgery fellowships are available, mastering the large breadth of the field should ideally begin early in training and may take several different pathways. The authors seek to provide a comprehensive list of resources for trainees interested in pediatric hand surgery, including training opportunities, educational tools, and networking organizations.

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Article Synopsis
  • The study aimed to evaluate whether releasing the first dorsal compartment during surgery for distal radius fractures improves symptoms in patients with pre-existing de Quervain disease.
  • A randomized cohort study was conducted with patients either undergoing compartment release or not, with results showing significant symptom improvement and better pinch strength in the release group at 3 and 6 months post-surgery.
  • The findings suggest that routinely performing this release during fracture treatment can help alleviate symptoms of de Quervain disease more effectively.
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We present two cases of complex metacarpal fractures treated with an intramedullary locking nail. This is an emerging fixation method that minimizes tissue insult, provides sufficient stability, and allows early mobilization. Locking nails accommodate the capture of fractured fragments in complex unstable patterns and provide longitudinal and rotational stability.

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Article Synopsis
  • Hand rotation and force application involve a coordinated effort between forearm bones, the interosseous ligament, and muscles.
  • The review provides a detailed analysis of the anatomy related to the forearm's functionality.
  • It highlights the mechanics of how these components work together to enable movement and manage external loads.
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The complications anticipated in the postoperative period after surgical resection of lateral ventricular neoplasms (LVN) are hemorrhage, hydrocephalus. At the N.N.

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Purpose: Multiple fixation methods with or without vascularized graft have been described to treat scaphoid nonunions. This study aimed to assess the incidence of carpal malalignment and the degree of ulnar carpal translocation after scaphoid volar plate fixation with pedicled vascularized bone graft in scaphoid waist nonunions with humpback deformity.

Methods: A retrospective cohort study of individuals with recalcitrant scaphoid fracture nonunion treated with volar scaphoid plating and vascularized bone graft was analyzed.

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Introduction: Pediatric firearm injury prevention research in younger age groups is limited. This study evaluated a large multicenter cohort of younger children with firearm injuries, focusing on injury patterns and surgical resource utilization.

Methods: Children ≤15 y old sustaining firearm injuries between 2016 and 2021 and treated at 10 pediatric trauma centers in Florida were included.

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