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Mexico Hospital[Affiliation] Publications | LitMetric

509 results match your criteria: "Mexico Hospital[Affiliation]"

An assessment of nationwide trends in emergency department (ED) resuscitative endovascular balloon occlusion of the aorta (REBOA) use - A trauma quality improvement program registry analysis.

Am J Surg

December 2024

Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Department of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, USA; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA; Center for Combat and Battlefield Research (COMBAT), University of Colorado School of Medicine, Aurora, CO, USA.

Article Synopsis
  • A study investigated the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) for managing severe torso trauma in emergency departments, highlighting its controversial role and limited data on patient outcomes.
  • The analysis included 3,398 REBOA procedures from 2017 to 2022, mostly involving male patients with an average age of 40, primarily stemming from collision injuries.
  • The findings showed that while survival rates were high (85%) shortly after REBOA placement, they declined significantly to 42% by discharge, indicating room for improvement in patient selection and outcomes.
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Objectives: In the United States, cannabis is legal for adult recreational use in 24 states and Washington, DC. Unintentional pediatric cannabis exposures have increased in many states following legalization.We evaluated the relationship between recreational cannabis legalization and the rates of unintentional pediatric exposures in a neighboring state that had not undergone legalization.

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Critical care transport medicine (CCTM) teams are playing an increasing role in the care of patients in cardiogenic shock requiring mechanical circulatory support devices. Hence, it is important that CCTM providers are familiar with the pathophysiology of cardiogenic shock, the role of mechanical circulatory support, and the management of these devices in the transport environment. The intra-aortic balloon pump is a widely used and accessible cardiac support device capable of increasing cardiac output and reducing work on the left ventricle through diastolic augmentation and counterpulsation.

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Introduction: Lumbar foraminal stenosis (LFS) occurs primarily due to degenerative changes in older adults, affecting the spinal foramina and leading to nerve compression. Characterized by pain, numbness, and muscle weakness, LFS arises from structural changes in discs, joints, and ligaments, further complicated by factors like inflammation and spondylolisthesis. Diagnosis combines patient history, physical examination, and imaging, while management ranges from conservative treatment to surgical intervention, underscoring the need for a tailored approach.

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Management of Diabetic Foot Ulcers with Two Forefoot Offloading Techniques: Case Series.

Adv Skin Wound Care

August 2024

In the Department of Orthopaedics and Rehabilitation, Center for Healing in the Lower Extremity, Albuquerque, New Mexico, USA, Leslie J. Dunlap, DMSc, MSPA-C, CWS, is Physician Assistant, University of New Mexico Hospital; and Eric Lew, DPM, FACFAS, is Associate Professor, University of New Mexico Health Sciences Center. In the Department of Rehabilitation Services, University of New Mexico Hospital, Regina Gallegos, MPT, CWS, and Richard Murdoch, PT, CWS, are Physical Therapists and Simone Mulvihill, PTA, is Physical Therapy Assistant.

Offloading is a key principle to healing diabetic foot ulcers. Nonremovable knee-high offloading devices are considered the criterion standard for offloading plantar forefoot ulcers. However, patients exhibit a limited tolerance for these devices, which contributes to a lack of use.

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Medication-use evaluations are meant to ensure that medication-use processes are consistent with prevailing standards of care, assure optimal use of therapy, and reduce the risk of medication-related problems. Reversal agents for direct oral anticoagulants are a worthy focus for medication-use evaluations for reasons of efficacy, safety, and cost. A multidisciplinary team of experts developed 2 medication-use evaluation templates illustrating the application of professional society guidelines to the appropriate use of andexanet alfa.

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Article Synopsis
  • Bidirectional ventricular tachycardia (BVT) is a rare and serious heart rhythm issue marked by changes in the QRS axis with each heartbeat, often linked to digitalis toxicity.
  • A 62-year-old woman who had heart surgery developed BVT after being treated with digoxin and diuretics, leading to concerns about the interaction between these medications.
  • The case stresses the need for careful monitoring of digoxin levels in patients on diuretics and suggests supportive treatments if BVT occurs, like stopping digoxin and providing potassium and magnesium supplements.
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Climate change and environmental sustainability in otolaryngology: A state-of-the-art review.

Surgeon

October 2024

Division of Otolaryngology - Head and Neck Surgery, Santa Clara Valley Medical Center, San Jose, CA, USA; Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.

Background: Climate change has been identified by the World Health Organization (WHO) as the greatest existing threat to human health. Given the direct exposure of the upper aerodigestive system to pollutants, patients in otolaryngology are at high risk for increased disease burden in the setting of climate change and worsening air quality. Given this and the environmental impact of surgical care, it is essential for surgeons to understand their role in addressing climate health through quality-driven clinical initiatives, education, advocacy, and research.

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Article Synopsis
  • Spinal surgery for conditions like myelopathy and radiculopathy demands both knowledge and precision, and advancements in 3D-printed cervical models are transforming surgical training by providing practical experience.
  • A study involving 20 neurosurgery residents demonstrated that these models effectively enhanced skills in tumor removal surgeries, receiving high satisfaction ratings for realism and training effectiveness.
  • The findings emphasize the importance of ongoing lab training for residents and highlight that these low-cost models are beneficial for all hospitals, improving surgical readiness regardless of resources.
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Article Synopsis
  • * This study utilized advanced techniques on samples from 1065 humans and 41 rhesus macaques to explore these connections, revealing a link between the posterior precuneus (POS2) and the temporal pole areas through the cingulum.
  • * Findings enhance our understanding of brain connectivity and could help integrate anatomical knowledge with functional roles in both healthy and diseased brains.
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Background: Few antiviral therapies have been studied in patients with coronavirus disease 2019 (COVID-19) and kidney impairment. Herein, the efficacy, safety, and pharmacokinetics of remdesivir, its metabolites, and sulfobutylether-β-cyclodextrin excipient were evaluated in hospitalized patients with COVID-19 and severe kidney impairment.

Methods: In REDPINE, a phase 3, randomized, double-blind, placebo-controlled study, participants aged ≥12 years hospitalized for COVID-19 pneumonia with acute kidney injury, chronic kidney disease, or kidney failure were randomized 2:1 to receive intravenous remdesivir (200 mg on day 1; 100 mg daily up to day 5) or placebo (enrollment from March 2021 to March 2022).

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The purpose of this article is to summarize pharmacotherapy related emergency medicine (EM) literature indexed in 2023. Articles were selected utilizing a modified Delphi approach. The table of contents from pre-determined journals were reviewed and independently evaluated via the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system by paired authors.

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Introduction: a relationship has been observed between elevated levels of liver enzymes and uric acid with the presence of metabolic syndrome (MS) in the pediatric population. Objective: to compare serum liver enzyme and uric acid levels between adolescents with and without MS. Methods: a cross-sectional study was carried out in adolescents with obesity between 10 and 18 years old.

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Article Synopsis
  • The OVIVA trial found that oral antibiotics are just as effective as IV antibiotics for treating osteoarticular infections (OAIs), prompting a survey of infectious disease physicians about their use of oral antibiotics.* -
  • Out of 413 responding physicians, 91% reported using oral antibiotics, primarily for diabetic foot osteomyelitis and joint infections, with various medications like trimethoprim-sulfamethoxazole and fluoroquinolones being commonly prescribed.* -
  • Although most physicians use oral antibiotics and chronic suppressive therapy (SAT) for OAIs, there is significant variation in practice and a general call for updated guidelines from the medical community.*
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Background: First classified in 2016, high-grade B-cell lymphoma (HGBCL) is a lymphoid neoplasm that is typically seen as an aggressive lymphoproliferative disorder (LPD). In most patients with HGBCL, various oncogene rearrangements present with advanced clinical features, such as central nervous system involvement. Patients with underlying autoimmune and rheumatologic conditions, such as rheumatoid arthritis, are at higher risk for developing LPDs, including highly aggressive subtypes of non-Hodgkin lymphomas such as HGBCL.

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Background: Ectopic cervical thymoma (ECT) is an extremely rare tumor, especially in association with myasthenia gravis (MG).

Case Presentation: We report a case of myasthenia gravis with an ectopic thymoma in the neck, whose myasthenic symptoms significantly improved after complete removal of the mass. A 55-year-old woman with generalized myasthenia gravis (MG) experienced worsening neuromuscular weakness after abruptly discontinuing pyridostigmine.

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Promoting Growth in Behavioral Neurology: A Path Forward.

Cogn Behav Neurol

June 2024

Division of Neuropsychiatry, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Behavioral neurology & neuropsychiatry (BNNP) is a field that seeks to understand brain-behavior relationships, including fundamental brain organization principles and the many ways that brain structures and connectivity can be disrupted, leading to abnormalities of behavior, cognition, emotion, perception, and social cognition. In North America, BNNP has existed as an integrated subspecialty through the United Council for Neurologic Subspecialties since 2006. Nonetheless, the number of behavioral neurologists across academic medical centers and community settings is not keeping pace with increasing clinical and research demand.

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Single-nucleus and spatial landscape of the sub-ventricular zone in human glioblastoma.

bioRxiv

April 2024

The Brain Tumor Translational Laboratory, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM.

The sub-ventricular zone (SVZ) is the most well-characterized neurogenic area in the mammalian brain. We previously showed that in 65% of patients with glioblastoma (GBM), the SVZ is a reservoir of cancer stem-like cells that contribute to treatment resistance and emergence of recurrence. Here, we built a single-nucleus RNA-sequencing-based microenvironment landscape of the tumor mass (T_Mass) and the SVZ (T_SVZ) of 15 GBM patients and 2 histologically normal SVZ (N_SVZ) samples as controls.

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Article Synopsis
  • The study evaluates how different frailty assessments (RAI and mFI-5) and patient age affect postoperative outcomes in neurosurgery, focusing on extended lengths of stay (eLOS), prolonged LOS within 30 days (pLOS), and LOS greater than 30 days.
  • The research analyzed data from over 400,000 patients and found that the RAI had better predictive ability for negative outcomes compared to mFI-5 and patient age.
  • The findings suggest that using the RAI for preoperative frailty screening can enhance patient care by improving quality metrics and preparing patients and families for surgical risks.
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This investigation assessed the impact of temporal resolution during a videofluoroscopic evaluation of swallowing (VFSS) on measures of duration and kinematics. Thirty adult and ten infant swallow studies, all acquired at 30 frames and 30 pulses per second, were obtained from a New Mexico hospital. All swallow studies were altered to simulate 15 and 5 pulses per second.

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Article Synopsis
  • The systematic review focused on the impact of frailty on outcomes for patients with chronic subdural hematoma (cSDH), highlighting frailty as a significant predictor of negative outcomes.
  • A total of six studies involving 4,085 patients were analyzed, revealing that frail patients experienced higher rates of mortality, complications, recurrence, and less favorable discharge dispositions compared to non-frail patients.
  • The authors concluded that more research with larger and consistent studies is necessary to confirm these findings, emphasizing the importance of assessing frailty for pre-operative risk evaluation in cSDH patients.
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The advent of patient access to complex medical information online has highlighted the need for simplification of biomedical text to improve patient understanding and engagement in taking ownership of their health. However, comprehension of biomedical text remains a difficult task due to the need for domain-specific expertise. We aimed to study the simplification of biomedical text via large language models (LLMs) commonly used for general natural language processing tasks involve text comprehension, summarization, generation, and prediction of new text from prompts.

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Primary hepatic liposarcoma is an extremely rare malignant tumour derived from adipocytes and is part of the group of mesenchymal tumours. We present the case of a 43-year-old Hispanic male patient with a pleomorphic hepatic liposarcoma and absence of MDM2 gene amplification. Two years and six months after surgery, the patient is asymptomatic.

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•Intracranial hemorrhage accounts for two out of every three major intracranial hemorrhages.•Systemic anticoagulation is routinely prescribed for prevention of cerebrovascular accidents.•The FDA approved Andexanet alfa to treat life-threatening bleeding.

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