80 results match your criteria: "Metro North Hospital and Health Services[Affiliation]"

Learning From Pregnant Women Eating 5 Servings or More of Vegetables Daily: Strategies, Behaviors, and Motivators.

J Nutr Educ Behav

January 2025

School of Medicine, University of Queensland, Brisbane, Queensland, Australia; Women's and Newborn Services, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.

Objective: To explore the context, behaviors, strategies, and motivators of pregnant women who consume 5 servings of vegetables daily.

Methods: Positive deviance study involving Australian pregnant women (9 of 529) identified through a validated food frequency questionnaire. Semistructured interviews explored their strategies, behaviors, and motivators.

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Phosphate is a predominately intracellular anion that has several key roles in normal cellular functions. Derangements in serum phosphate concentration occur frequently during critical illness, particularly hypophosphataemia, which has been reported in up to 75% of Intensive Care Unit (ICU) patients. The association between hypophosphataemia and ICU outcomes reported in the literature are conflicting and and subject to substantial confounding.

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Article Synopsis
  • The study aimed to analyze the prevalence of in-person visits and virtual communication methods (like phone and video calls) in ICUs across Australia and New Zealand, especially during the COVID-19 pandemic.
  • Findings revealed that 77% of ICUs had visiting restrictions, with a significantly reduced median visiting time of 9 hours per day, resulting in only 65% of patients receiving in-person visits.
  • The majority of in-person visits were for family interaction, while telephone calls were primarily for clinical updates, with visit patterns showing higher activity during daytime hours rather than the evening.
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Article Synopsis
  • Critically ill patients in Australia and New Zealand often don't meet energy and protein targets with oral nutrition, especially compared to those who start enteral or parenteral nutrition in ICU.
  • The study analyzed data from 409 patients across 44 hospitals to compare outcomes, focusing on energy delivery and nutrition assessment during hospital stays.
  • Results showed that patients on oral nutrition had lower energy and protein intake, fewer invasive interventions, and received less nutrition assessment compared to those who switched to enteral or parenteral nutrition.
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D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care.

Crit Care

November 2024

Division of Perioperative, Acute, Critical Care and Emergency Medicine, Department of Medicine, University of Cambridge, Level 4, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

Article Synopsis
  • The D-PRISM study investigated global practices for diagnosing and treating pneumonia in ICU settings, focusing on community-acquired, hospital-acquired, and ventilator-associated pneumonia across different countries.
  • A survey gathered responses from 1,296 ICU clinicians across 72 countries, revealing varied diagnostic processes and a lack of standardized microbiological testing, particularly in lower-income regions.
  • Findings indicated that the typical antibiotic treatment duration was 5-7 days, with shorter durations linked to effective antimicrobial stewardship programs in higher-income countries.
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Article Synopsis
  • - A study was conducted to identify barriers and enablers for completing a trainee research project required for CICM Fellowship, using a two-stage modified Delphi method involving surveys and a consensus panel.
  • - The survey gathered responses from CICM trainees, supervisors, and researchers across Australia and New Zealand, leading to a total of 88 responses and subsequent discussions among a panel of 30 experts.
  • - The final outcome was the creation of 22 consensus-based recommendations aimed at improving the efficiency of completing the CICM research project and enhancing the quality of the resulting research.
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Background: Artificial intelligence (AI)-based tools have shown promise in histopathology image analysis in improving the accuracy of oral squamous cell carcinoma (OSCC) detection with intent to reduce human error.

Objectives: This systematic review and meta-analysis evaluated deep learning (DL) models for OSCC detection on histopathology images by assessing common diagnostic performance evaluation metrics for AI-based medical image analysis studies.

Methods: Diagnostic accuracy studies that used DL models for the analysis of histopathological images of OSCC compared to the reference standard were analyzed.

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Causal analyses in longitudinal observational studies in oral health: A scoping review.

Community Dent Oral Epidemiol

February 2025

School of Dentistry, Faculty of Health and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia.

Objective: Causal analysis including causal inference and causal mediation is pivotal to inform effective interventions. In modern epidemilogy, causal analysis involves four key steps: formulating causal questions, employing directed acyclic graphs (DAGs), conducting data management and selecting statistical strategies. Our objective was to conduct a scoping review to assess how longitudinal observational studies (LOSs) in dental field have integrated these four steps to contribute leverage evidence that inform oral public health interventions.

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A systematic review of health state utility values for older people with acute myeloid leukaemia.

Qual Life Res

November 2024

Deakin Health Economics, School of Health and Social Development, Deakin University, Melbourne, VIC, Australia.

Purpose: Older people with acute myeloid leukaemia (AML) have a poor prognosis, reduced health-related quality of life (HRQoL) and require substantial healthcare resources. The objectives of this systematic review were to determine what health state utility values (HSUVs) are reported in the literature that can be used in economic evaluations of interventions for older people with AML, identify research gaps, and discuss directions for future research.

Methods: The following databases were searched for studies published from inception until Feb 2023: PubMed, EMBASE, CINAHL, PsycINFO, Cochrane, and EconLit.

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Background: Decision-making in dentistry is a complex process, and this study evaluated factors that influence dentists' approaches in permanent mature teeth with irreversible pulpitis.

Methods: An online questionnaire was distributed to a group of dental practitioners. The questionnaire surveyed dentists' opinions about the management of vital permanent teeth with irreversible pulpitis including a case scenario.

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Article Synopsis
  • Oral epithelial dysplasia (OED) is a precancerous condition linked to oral squamous cell carcinoma (OSCC), with diagnosis primarily reliant on histopathological examination, which can be inconsistent among different observers.
  • This review article analyzes the role of artificial intelligence (AI), specifically deep learning and machine learning, in improving OED diagnosis using histopathology images.
  • The findings highlight that while AI methods show promise in enhancing diagnostic accuracy and prognosis predictions for OED, more research is needed to address challenges such as the generalization of results and the interpretability of AI models.
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: Locked plating for distal femur fractures is widely recommended and used. We systematically reviewed clinical studies assessing the benefits and harms of fracture fixation with locked plates in AO/OTA Type 32 and 33 femur fractures. : A comprehensive literature search of PubMed, Embase, Cinahl, Web of Science, and the Cochrane Database was performed.

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Introduction: Oral Health Therapists (OHTs) are a growing workforce globally, with skills in oral health prevention, treatment planning and management of disease. These professionals receive their training through a three-year undergraduate program which leads to the Bachelor of Oral Health degree in Australia and New Zealand. The aim of this study was to describe the learning environment for OHT students in Australia and New Zealand.

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Background: There is an increased tendency towards adopting minimally invasive interventions in dentistry, supported by advancement in materials and techniques. However, the decision-making process in choosing conservative or invasive treatments is influenced by several factors, particularly in permanent teeth with irreversible pulpitis.

Objectives: The objective of the study was to systematically review the literature regarding factors that influence decision-making for vital pulp therapy (VPT) as definitive treatment option in permanent mature teeth diagnosed with irreversible pulpitis.

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Antibiotic de-escalation: finally, some action and not only words.

Lancet Infect Dis

April 2024

Department of Anesthesiology and Intensive Care Unit, Hospital Nord, Aix Marseille University, Assistance Publique Hôpitaux Universitaires de Marseille, Marseille, France.

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Purpose: To explore how vocational rehabilitation (VR) is currently delivered for individuals with acquired brain injury (ABI) across multiple stakeholder groups and identify areas for improvement in service delivery using the Consolidated Framework for Implementation Research (CFIR).

Methods: Seven focus groups were conducted with rehabilitation clinicians; outreach providers, insurers/regulators, VR providers and disability employment service providers ( = 44) experienced in VR of individuals with ABI. All groups were audio-recorded and transcribed verbatim.

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Cannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study.

J Crit Care

April 2024

Department of Intensive Care Services, Royal Brisbane and Womens Hospital, Brisbane, Queensland, Australia; Queensland University of Technology (QUT), Brisbane, Queensland, Australia.

Purpose: To identify factors associated with cannabinoid use among patients admitted to ICU and its impact on survival.

Methods: A cohort of adult patients admitted to four public Australian ICUs was assembled. Individuals with mental and behavioural disorders related to cannabinoids were identified using ICD10-AM codes.

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Fluid therapy in diabetic ketoacidosis.

Curr Opin Clin Nutr Metab Care

March 2024

Critical Care Division, The George Institute for Global Health, Sydney, New South Wales.

Purpose Of Review: To evaluate recent evidence (2021-2023) on fluid therapy in diabetic ketoacidosis. Key evidence gaps which require generation of new evidence are discussed.

Recent Findings: Balanced crystalloid solutions, compared to the commonly recommended and used 0.

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Breakthrough SARS-COV-2 infection induces broad anti-viral T cell immunity.

iScience

December 2023

QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia.

Vaccines have curtailed the devastation wrought by COVID-19. Nevertheless, emerging variants result in a high incidence of breakthrough infections. Here we assess the impact of vaccination and breakthrough infection on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T cell immunity.

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Balanced crystalloids versus saline for critically ill patients (BEST-Living): a systematic review and individual patient data meta-analysis.

Lancet Respir Med

March 2024

The George Institute for Global Health, Sydney, NSW, Australia; University of New South Wales, Sydney, NSW, Australia; School of Public Health, Imperial College London, London, UK. Electronic address:

Background: The effect of balanced crystalloids compared with that of saline in critically ill patients overall and in specific subgroups is unclear. We aimed to assess whether use of balanced solutions, compared with 0·9% sodium chloride (saline), decreased in-hospital mortality in adult patients in intensive care units (ICUs).

Methods: For this systematic review and individual patient data meta-analysis, we searched PubMed, Embase, and CENTRAL databases from inception until March 1, 2022 (updated Sept 1, 2023) for individually randomised and cluster-randomised trials comparing balanced solutions with saline for adult patients in the ICU.

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Biofabrication approaches toward the development of tissue-engineered vascular grafts (TEVGs) have been widely investigated. However, successful translation has been limited to large diameter applications, with small diameter grafts frequently failing due to poor mechanical performance, in particular mismatched radial compliance. Herein, melt electrowriting (MEW) of poly(-caprolactone) has enabled the manufacture of highly porous, biocompatible microfibre scaffolds with physiological anisotropic mechanical properties, as substrates for the biofabrication of small diameter TEVGs.

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Background: Globally there are high numbers of patients with palliative care needs receiving care in hospitals. Patient reported experience measures (PREMs) provide useful data to guide improvement work. How to implement PREMs within palliative care populations is unclear.

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Generative Adversarial Networks in Digital Histopathology: Current Applications, Limitations, Ethical Considerations, and Future Directions.

Mod Pathol

January 2024

Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, Maryland; Division of Artificial Intelligence Research, University of Maryland School of Dentistry, Baltimore, Maryland; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland. Electronic address:

Generative adversarial networks (GANs) have gained significant attention in the field of image synthesis, particularly in computer vision. GANs consist of a generative model and a discriminative model trained in an adversarial setting to generate realistic and novel data. In the context of image synthesis, the generator produces synthetic images, whereas the discriminator determines their authenticity by comparing them with real examples.

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Determinants of 90-day case fatality among older patients admitted to intensive care units: A retrospective cohort study.

Aust Crit Care

January 2024

Queensland University of Technology, Brisbane, Queensland, Australia; Department of Intensive Care Services, Royal Brisbane and Womens Hospital, Brisbane, Queensland, Australia.

Background: A recent systematic review identified highly variable case-fatality rates among studies of older patients admitted to intensive care units (ICUs). However, structural and process determinants including patient resident status, tertiary ICU status, and treatment limitations were unavailable.

Objective: The objective of this study was to evaluate the role of determinants such as resident status, tertiary ICU, and treatment limitations on 90-day case fatality among older ICU patients.

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Central line associated and primary bloodstream infections.

Curr Opin Crit Care

October 2023

Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Royal Brisbane and Women's Hospital Campus, Brisbane.

Purpose Of Review: Primary and intravascular catheter-associated bloodstream infections (CA-BSIs) represent an important clinical entity in the intensive care unit (ICU) being associated with significant morbidity and mortality. The purpose of this review was to examine the recently published data on epidemiology and management of CA-BSI and other primary BSIs specifically within the context of the ICU.

Recent Findings: In critically ill patients, the pooled prevalence of primary and CA-BSI from contemporary studies was 19.

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