2 results match your criteria: "Methodist University IPA Santo Antônio Children's Hospital[Affiliation]"

Endobronchial perfluorocarbon reduces inflammatory activity before and after lung transplantation in an animal experimental model.

Mediators Inflamm

October 2014

Postgraduate Program in Pulmonology, Federal University of Rio Grande do Sul (UFRGS), 90040-060 Porto Alegre, RS, Brazil ; Thoracic Surgery Department, Laboratory of Airways and Lung, Hospital de Clínicas de Porto Alegre (HCPA), Ramiro Barcelos 2.350, 90035-903 Porto Alegre, RS, Brazil ; Santo Antônio Children's Hospital, 90020-090 Porto Alegre, RS, Brazil.

Background: The aim of this study was to evaluate the use of liquid perfluorocarbon (PFC) as an adjuvant substance for lung preservation and assess its role in pulmonary protection after transplantation.

Methods: Seventy-two rat lungs were flushed with low-potassium dextran (LPD) solution and randomized into three main groups: control with LPD alone and experimental with 3 (PFC3) and 7 mL/kg (PFC7) of endobronchial PFC instilled just after harvest. Each group was divided into four subgroups according to preservation time (3, 6, 12, and 24 hours).

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Objective: To assess factors associated with failure in ventilatory weaning of children undergone surgical correction of congenital heart diseases.

Methods: Cohort study with 29 children. The heart diseases were divided into cyanotic (nine children) and acyanotic (20 children).

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