16 results match your criteria: "Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute[Affiliation]"
Neuromodulatory Approaches for Atrial Fibrillation Ablation.
Eur Cardiol
February 2021
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital Houston, TX, US.
In this review, the authors describe evolving alternative strategies for the management of AF, focusing on non-invasive and percutaneous autonomic modulation. This modulation can be achieved - among other approaches - via tragus stimulation, renal denervation, cardiac afferent denervation, alcohol injection in the vein of Marshall, baroreceptor activation therapy and endocardial ganglionated plexi ablation. Although promising, these therapies are currently under investigation but could play a role in the treatment of AF in combination with conventional pulmonary vein isolation in the near future.
View Article and Find Full Text PDFCoronary vein defibrillator coil placement in patients with high defibrillation thresholds.
J Arrhythm
February 2019
Background: Elevated defibrillation threshold (DFT) occurs in 2%-6% of patients undergoing implantable cardioverter defibrillator (ICD) implantation. Adding a defibrillation coil in the coronary sinus (CS) or its branches can result in substantial reductions in the mean DFT. However, data regarding acute success and long-term stability remain lacking.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how ethanol infusion into the vein of Marshall (EI-VOM) affects the mitral isthmus (MI) in patients undergoing atrial fibrillation ablation.
- Patients' atrial electrograms (AECSs) were analyzed, revealing that EI-VOM can isolate the left atrial myocardium (LAM) from the coronary sinus musculature (CSM).
- The findings suggest that careful monitoring of AECSs can help predict whether additional radiofrequency catheter (RFCS) ablation is needed, with 93% of patients achieving successful conduction block at the MI.
The Cost Effectiveness of LAA Exclusion.
J Atr Fibrillation
February 2016
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas.
Left atrial appendage (LAA) exclusion strategies are increasingly utilized for stroke prevention in lieu of oral anticoagulants. Reductions in bleeding risk and long-term compliance issues bundled with comparable stroke prevention benefits have made these interventions increasingly attractive. Unfortunately, healthcare funding remains limited.
View Article and Find Full Text PDFCombination of Hansen Robotic system with cryocatheter in a challenging parahisian accessory pathway ablation.
Indian Pacing Electrophysiol J
August 2016
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, TX, USA.
Article Synopsis
- Cryoablation generally allows for solid stability (cryoadherence) of the catheter tip during cold temperatures, even when the heart is beating rapidly (tachycardia).
- A case was reported involving a young patient with a specific heart condition (parahisian accessory pathway) where this stability was not attained using a standard cryocatheter and steerable sheath.
- Ultimately, the stability was successfully achieved using a robotic system, specifically the Hansen system.
Article Synopsis
- The autonomic nervous system is essential for normal heart function and significantly influences various cardiovascular diseases.
- Advances in neuroscience are highlighting the potential of new cardiovascular treatments.
- This White Paper examines human cardiac neuroanatomy, the impact of diseases, testing methods, risk evaluation, and neuromodulation strategies for improving heart health.
Strategies for phrenic nerve preservation during ablation of inappropriate sinus tachycardia.
Heart Rhythm
June 2016
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, Houston Methodist Hospital, Houston, Texas.
Article Synopsis
- Radiofrequency ablation is effective in treating drug-resistant inappropriate sinus tachycardia (IST), but complications like phrenic nerve injuries remain a concern.
- Researchers analyzed procedures from 13 female patients undergoing RF ablation for IST and found that changing access points improved efficiency and reduced fluoroscopy time.
- The study concluded that certain techniques, like ventilation holding and anterior pericardial access, help avoid complications and enhance long-term symptom control, showing an 84.6% success rate post-procedure.
Ligament and vein of Marshall: A therapeutic opportunity in atrial fibrillation.
Heart Rhythm
February 2016
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas. Electronic address:
Atrioventricular Junction Ablation In Atrial Fibrillation: Choosing The Right Patient And Pacing Device.
J Atr Fibrillation
August 2015
Cardiac Arrhythmia and Electrophysiology Unit, Department of Cardiology, Hospital Virgen de la Salud, Toledo, Spain.
Article Synopsis
- Atrial fibrillation (AF) is a common heart condition that can't always be treated effectively with rhythm control, leaving many patients relying on rate control methods.
- Some patients experience symptoms and risks related to ineffective pharmacological rate control, such as heart failure.
- Catheter ablation of the atrioventricular junction, followed by a permanent pacemaker, can offer reliable rate control, especially for patients with heart failure and reduced function.
Ethanol infusion in the vein of Marshall leads to parasympathetic denervation of the human left atrium: implications for atrial fibrillation.
J Am Coll Cardiol
May 2014
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas. Electronic address:
Objectives: This study sought to determine whether ethanol infusion in the vein of Marshall (VOM) can ablate intrinsic cardiac nerves (ICN).
Background: ICN cluster around the left atrial epicardium and are implicated in the genesis of atrial fibrillation (AF).
Methods: Patients undergoing catheter AF ablation underwent adjunctive ethanol injection in the VOM.
Effect of Age on Outcomes of Catheter Ablation of Atrial Fibrillation.
J Atr Fibrillation
June 2013
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas.
Article Synopsis
- Age significantly influences the development of atrial fibrillation (AF), particularly in older individuals, increasing their risk for serious health issues like stroke and heart failure.
- Recent advancements in treatment, especially catheter ablation, have improved management of AF, enhancing life quality and reducing morbidity and mortality.
- Despite these benefits, older patients have not fully reaped the rewards of catheter ablation due to insufficient evidence from randomized trials, leading to a preference for rate-control strategies for this age group.
Role of the vein of Marshall in atrial fibrillation recurrences after catheter ablation: therapeutic effect of ethanol infusion.
J Cardiovasc Electrophysiol
June 2012
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, TX, USA.
Article Synopsis
- Atrial fibrillation (AF) can persist after initial treatment using pulmonary vein isolation (PVAI), and the vein of Marshall (VOM) may contribute to these recurrences; the study explores the potential of VOM ethanol infusion as a treatment.
- In a study involving 61 patients, VOM was accessed in 54, with signals recorded, but it was found that VOM did not consistently trigger AF; however, ethanol infusion effectively eliminated reconnections in a significant number of patients.
- The study concludes that while VOM may play a minor role in AF recurrence, infusing ethanol into the VOM can help restore disconnection between the pulmonary veins, thus providing a therapeutic option for those with recurrent
Ethanol infusion in the vein of Marshall facilitates mitral isthmus ablation.
Heart Rhythm
August 2012
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas, USA.
Background: Treatment of perimitral flutter (PMF) requires bidirectional mitral isthmus (MI) block, which can be difficult with radiofrequency ablation (RFA). The vein of Marshall (VOM) is located within the MI.
Objective: To test whether VOM ethanol infusion could help achieve MI block.
Robotic catheter ablation of left ventricular tachycardia: initial experience.
Heart Rhythm
December 2011
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas 77030, USA.
Article Synopsis
- The study assessed the feasibility of using the Hansen Sensei Robotic system for catheter ablation of ventricular tachycardia in the left ventricle, which is challenging due to catheter positioning and contact stability.
- A total of 23 patients were involved, and the procedure was performed entirely with robotic assistance, leading to successful mapping and ablation, with minimal complications.
- Follow-up showed a recurrence of ventricular tachycardia in 3 out of 23 patients after an average of 13.4 months, indicating the robotic system's potential effectiveness for this procedure.
Ethanol infusion in the vein of Marshall: Adjunctive effects during ablation of atrial fibrillation.
Heart Rhythm
November 2009
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas 77030, USA.
Background: The vein of Marshall (VOM) is a left atrial (LA) vein that contains autonomic innervation and triggers of AF. Its location coincides with areas usually ablated during pulmonary vein (PV) antral isolation (PVAI).
Objective: This study sought to delineate the safety and ablative effects of ethanol infusion in the VOM during catheter ablation of atrial fibrillation (AF).
Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease.
J Am Coll Cardiol
August 2008
Department of Cardiology, Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, Houston, Texas, USA.
Objectives: The aim of this study was to evaluate the relationship between reticulated platelets (RPs), platelet size, and platelet function in patients with stable coronary artery disease (CAD) taking aspirin and clopidogrel.
Background: Reticulated platelets are young platelets that are larger and possibly more active than non-RPs.
Methods: Flow cytometry was used to measure RPs after staining with thiazole orange and to define the upper 20% and lower 20% of platelets by size.