4,491 results match your criteria: "Methemoglobinemia"
Treatment of congenital chyloperitoneum is a challenge. Conservative methods may be ineffective. Preoperative visualization of the site of lymphatic leakage is crucial, but radiological imaging is technically complicated and may not provide sufficient information, especially in small patients.
View Article and Find Full Text PDFPerfusion
April 2024
Department of Pediatrics, Congenital Heart Center, University of Florida, Gainesville, FL, USA.
Nitric Oxide (NO) is a naturally occurring modulator of inflammation found in the human body. Several studies in the pediatric cardiothoracic surgery literature have demonstrated some beneficial clinical effects when NO is added to the sweep gas of the cardiopulmonary bypass circuit. Our primary aim was to determine the safety of incorporating nitric oxide into the oxygenator sweep gas of the extracorporeal membrane oxygenation (ECMO) circuit.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
April 2024
Department of Dermatology, Medical Center, University of Freiburg, Hauptstrasse 7, 79104, Freiburg, Germany.
Toxicol Rep
June 2024
Department of Pathology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Methemoglobinemia is a potentially life-threatening condition caused by the formation of methemoglobin, a form of hemoglobin that cannot bind oxygen. While there are some rare congenital causes of methemoglobinemia, most cases are acquired from the effects of specific drugs or environmental exposures. In this retrospective study, we analyzed a large data set of whole blood samples analyzed for methemoglobin at an academic medical center in Midwestern United States that provides both pediatric and adult services.
View Article and Find Full Text PDFRev Neurosci
July 2024
Research Center of Neurology, 125367, Moscow, Russia.
Traumatic brain injury (TBI) and brain ischemia/reperfusion cause neurodegenerative processes that can continue after the acute stage with the development of severe brain atrophy with dementia. In this case, the long-term neurodegeneration of the brain is similar to the neurodegeneration characteristic of Alzheimer's disease (AD) and is associated with the accumulation of beta amyloid and tau protein. In the pathogenesis of AD as well as in the pathogenesis of cerebral ischemia and TBI oxidative stress, progressive inflammation, glial activation, blood-brain barrier dysfunction, and excessive activation of autophagy are involved, which implies the presence of many targets that can be affected by neuroprotectors.
View Article and Find Full Text PDFJ Med Case Rep
March 2024
National Hospital Kandy, Kandy, Sri Lanka.
Background: Herbal products and traditional remedies are commonly used by individuals worldwide for the management of common ailments, even though most are not without risks. Acalypha indica is a popular medicinal plant consumed in some Asian countries.
Case Presentation: This case report presents a 40-year-old previously unevaluated Sri Lankan female and her 8-year-old son who presented with severe glucose-6-phosphate dehydrogenase (G6PD) deficiency related acute intravascular oxidative haemolysis and methaemoglobinaemia precipitated by Acalypha indica consumption, successfully managed with supportive care and blood transfusion.
Cureus
February 2024
General Medicine, Sengkang General Hospital, Singapore, SGP.
Zopiclone is a sedative-hypnotic that is increasingly being used for insomnia, especially among patients with depression. The side effects of zopiclone include nausea, vomiting, headache, giddiness, sedation, altered mental status, and coma. Here, we describe a rare case of a patient with underlying depression who overdosed on zopiclone, resulting in a presentation of drowsiness and dyspnea.
View Article and Find Full Text PDFPerfusion
March 2024
Department of Emergency and Intensive Care, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Turk Arch Pediatr
January 2024
Department of Pediatric Critical Care Medicine, Ankara University Faculty of Medicine, Ankara, Turkey.
Cite this article as: Karaçoban G, Gurbanov A, Özen H, Gün E, Çakmaklı HF, Kendirli T. Successful treatment with ascorbic acid in a case of methemoglobinemia due to glucose-6-phosphate dehydrogenase deficiency. Turk Arch Pediatr.
View Article and Find Full Text PDFClin Pediatr (Phila)
December 2024
Physiopathology of Anemias Unit, Hematology and CTMO Unit, Foundation IRCSS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Trop Doct
July 2024
Department of Medicine, National University Hospital, Singapore, Singapore.
Cureus
January 2024
Anaesthesiology, All India Institute of Medical Sciences, Bathinda, Bathinda, IND.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common X-linked recessive red blood cell disease in humans. The highest prevalence of G6PD deficiency is reported to be in Africa, Southern Europe, the Middle East, Southeast Asia, and the islands of the Central and South Pacific. G6PD deficiency causes acute hemolysis upon exposure to oxidative stress.
View Article and Find Full Text PDFTransplant Proc
March 2024
Nephrology, St Vincent's Hospital, Sydney, Australia.
We describe the case of a 51-year-old Caucasian man with a background of a cardiac and renal transplant who developed Enterocytozoon bieneusi colitis and pneumocystis jirovecii (PJP) pneumonia following treatment for suspected rejection. The patient developed methemoglobinemia which was attributed to primaquine. He was treated with intravenous methylene blue leading to clinical and biochemical resolution.
View Article and Find Full Text PDFCureus
January 2024
Internal Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Acquired methemoglobinemia is a treatable condition that is often clinically subtle and can be missed on routine clinical assessment. We present a 73-year-old male who was evaluated in the emergency department with worsening respiratory symptoms requiring oxygen. He tested COVID-19 positive and had new pulmonary emboli evident on his CT chest.
View Article and Find Full Text PDFCureus
January 2024
Anaesthesiology, Southend University Hospital, Mid and South Essex NHS Foundation Trust, Southend-on-Sea, GBR.
Food Res Int
February 2024
Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea. Electronic address:
Clin Med Insights Pediatr
January 2024
Department of Pediatrics, Military Hospital of Tunis, Tunis, Tunisia.
PLoS Negl Trop Dis
January 2024
Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation (INI/Fiocruz), Rio de Janeiro, RJ, Brazil.
Background: The occurrence of adverse drug events (ADEs) during dapsone (DDS) treatment in patients with leprosy can constitute a significant barrier to the successful completion of the standardized therapeutic regimen for this disease. Well-known DDS-ADEs are hemolytic anemia, methemoglobinemia, hepatotoxicity, agranulocytosis, and hypersensitivity reactions. Identifying risk factors for ADEs before starting World Health Organization recommended standard multidrug therapy (WHO/MDT) can guide therapeutic planning for the patient.
View Article and Find Full Text PDFAm J Trop Med Hyg
March 2024
Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Leprosy is a global health issue, causing long-term functional morbidity and stigma. Rapid diagnosis and appropriate treatment are important; however, early diagnosis is often challenging, especially in nonendemic areas. Here, we report a case of borderline lepromatous leprosy accompanied by dapsone-induced (neutropenia, anemia, and methemoglobinemia) and clofazimine-induced (skin discoloration and ichthyosis) side effects and type 1 leprosy reactions during administration of the multidrug therapy.
View Article and Find Full Text PDFArch Pediatr
February 2024
Department of Pediatrics, Centre Hospitalier Henri Duffaut, Avignon, France.
J Contam Hydrol
February 2024
Polymer Research Laboratory, Department of Chemistry, Acharya Narendra Dev College, (University of Delhi), Govindpuri, Kalkaji, New Delhi - 110019, India. Electronic address:
Groundwater, a vital global resource, is essential for sustaining life and various human activities. However, its quality and availability face increasing threats from both natural and human-induced factors. Widespread contamination, arising from both natural origins and human activities such as agriculture, industry, mining, improper waste disposal, and wastewater release, poses significant risks to human health and water security.
View Article and Find Full Text PDFBr J Anaesth
April 2024
Department of Anaesthesiology and Critical Care Medicine, Merheim Medical Center, Witten/Herdecke University, Cologne, Germany.
Ann Med Surg (Lond)
January 2024
Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.