Synthesis, photo-physicochemical and biological properties of novel tetrahydropyrimidone-substituted metallo-phthalocyanines.

In this study, new peripherally substituted symmetric zinc and magnesium phthalocyanines (4 and 5) were successfully prepared by cyclotetramerization of the tetrahydropyrimidone (THPM)-linked phthalonitrile 3. The identity of the compounds were confirmed primarily through spectroscopic analysis including NMR, FT-IR, UV-Vis and MALDI-TOF mass spectroscopy. The photophysical and photochemical properties of the synthesized phthalocyanines (Pcs) were examined using UV-Vis absorption and fluorescence emission spectroscopy techniques.

Clinical and Surgical Results of Treatment Modalities in Orbital Roof Fractures: Single-Center Experience.

Orbital roof fractures are uncommon craniofacial fractures. Due to the location of the fracture and the mechanism of trauma, it is often associated with neuroophthalmological injuries. The authors aimed to evaluate the results of conservative and surgical treatments of patients with orbital roof fractures and present our clinical experiences regarding optimal treatment planning, especially in cases of moderate or severe head trauma.

Protein nanocarrier-enabled plant genetic engineering systems.

Genetic engineering can enhance crop yields by developing climate-resilient crop varieties. Nanobiotechnology plays a crucial role in precision delivery of genetic materials, nutrients, and stress-responsive agents into plant cells. This forum highlights recent advances in biodegradable protein-based nanocarrier systems for plant genome editing to transform agricultural practices.

Design of a high voltage gain converter using coupled inductor with reduced voltage stress for photovoltaic energy based systems.

This paper presents the design and analysis of a high voltage gain converter utilizing a coupled inductor with reduced voltage stress, specifically for photovoltaic energy-based systems. The proposed converter employs a two-winding coupled inductor and voltage multiplier cells to achieve an increase in output voltage while mitigating voltage stress across semiconductor components. Additionally, the voltage multiplier cells function as voltage clamps for the power switch, further enhancing the converter's performance.

From cornfield to catalyst support: Eco-friendly synthesis of Cu/CuO nanoparticles, immobilization on the waste corn husk fibers, photocatalytic exploration and bioactivity evaluation.

This study presents an innovative approach to eco-friendly synthesis and utilization of copper nanoparticles (CuNPs) for photocatalytic applications, employing waste corn husk fibers as sustainable catalyst support. The synthesis of CuNPs was achieved through a green synthesis method utilizing myrtle extract. Subsequently, the remarkable photocatalytic activity of the CuNPs explored (76% removal efficiency of Crystal Violet), showcased their potential in environmental remediation applications.

A new scoring system to predict survival in elderly advanced stage Hodgkin lymphoma patients.

Predictive prognostic scoring (PS) systems are not primarily applicable to elderly patients with classical Hodgkin lymphoma (cHL). The objective of this study was to develop a PS system for these patients. The derivation cohort (DC) was utilized for model development, consisting of 97 variables.

Congenital Brain Tumors: Surgical Outcomes and Long-Term Prognostic Factors.

Objective: To evaluate long-term outcomes of surgical resection for congenital brain tumors (CBTs) in infants under one year of age and to identify factors related to survival.

Methods: Our retrospective study analyzed infants who underwent gross total or subtotal resection (STR) for CBTs between 2001 and 2019. Data were obtained from medical records, including demographics, clinical presentation, diagnosis, tumor characteristics, and presence of hydrocephalus.

Dynamic factors driving PM2.5 concentrations: Fresh evidence at the global level.

This paper analyzes the dynamic impact of economic, social, and governance factors on PM2.5 concentrations in 89 countries from 2006 to 2019. Using the GMM-PVAR approach and Impulse-Response Functions, we examine how shocks to specific variables affect PM2.

Heavy metal levels of outdoor dust from the Eastern Mediterranean Sea region and assessment of the ecological and health risk.

As a result of some chemical element (heavy metals) pollution of dust, environmental pollution of dust has become an increasing concern, necessitating an assessment of risks to both ecology and human health, particularly in urban areas. Most of these pollutants settle on the outdoors and eventually become part of the outdoor dust. These will have negative long-term repercussions on ecosystems and human health.

Standard operating procedure for the analysis of major ions in hydrothermal fluids by ion chromatography.

This standard operating procedure (SOP) describes an ion chromatography (IC) procedure for the major cations and anions in hydrothermal fluids. Hydrothermal fluids are aqueous solutions with a wide range of temperature, salinity, pH and ion species that can be used by microbial metabolism as electron donors and electron acceptors. Due to the high variability of the environmental physical-chemical parameters in these samples, we have developed this protocol taking into account the special features of the matrices analyzed.

Investigation of the anticancer effect of newly synthesized palladium conjugate Schiff base metal complexes on non-small cell lung cancer cell line and mouse embryonic fibroblast cell line.

Lung cancer remains one of the leading causes of death worldwide. Due to the side effects of chemotherapeutic agents on normal cells and the development of resistance by cancer cells, there is an urgent need for alternative new pharmacological agents. Palladium (Pd)-conjugated Schiff base (SB) compounds represent an alternative approach with promising potential applications in cancer treatment.

Development of mesoporous magnetic nanoparticles supported idarubicin and investigation of apoptotic and cytotoxic effects on cancer cell lines.

Background: Many methods are used for cancer treatment, especially chemotherapy. In addition to the their therapeutic effects, chemotherapeutic drugs also have serious disadvantages, such as not being cell and tissue-specific, causing toxicity in many tissues, and developing drug resistance. Many methods, especially nanocarriers, have been designed to overcome these disadvantages.

Endoplasmic Reticulum Stress in Myometrial Smooth Muscle Cells and Spontaneous Contraction Changes in the Uterus of Dehydroepiandrosterone-induced Polycystic Ovary Syndrome Rats.

Myometrial changes in polycystic ovary syndrome (PCOS) are poorly investigated. Thus, we aimed to investigate endoplasmic reticulum (ER) stress in myometrial smooth muscle cells and changes in spontaneous uterine contraction in PCOS. Twenty-one female Sprague-Dawley rats (21 days old) were divided into control (n = 7), vehicle (n = 7) and PCOS (n = 7) groups.

The effect of virtual reality glasses on pain and patient satisfaction in arteriovenous fistula cannulation procedure.

Aims: To determine the effect of virtual reality glasses intervention on pain, vital signs, and patient satisfaction of hemodialysis patients undergoing AVF catheter puncture.

Design: Randomized controlled study.

Methods: The study was conducted in 60 patients receiving dialysis treatment in the HD unit of a public hospital in Turkey.

Innovative boxing training program outperforms the traditional scapular stabilization training program in post-stroke patients.

Facilitating the restoration of upper limb functionality is a key objective of stroke rehabilitation. This study aimed to compare the effects of boxing and scapular stabilization training on scapular mobility, balance angle, muscle strength, motor function, and satisfaction in hemiparetic patients. A total of sixty patients were randomly assigned to one of three groups: the boxing group (BG; n = 20), the scapular stabilization group (SSG; n = 20), or the control group (CG; n = 20) which received no treatment at all.

Did the Coronavirus Disease 2019 (COVID-19) Pandemic Cause a Delay in the Diagnosis of Breast Cancer Patients?

Introduction The coronavirus disease 2019 (COVID-19) outbreak, first reported in Wuhan, China, in December 2019, quickly hit the world in just one month, causing a global public health emergency. We aimed to investigate whether the COVID-19 pandemic caused a delay in the hospital admissions of breast cancer patients and diagnosis of breast cancer, thus increasing the tumor size and the stage of the disease. Materials and methods Included in the study were patients who underwent breast cancer surgery between 01/03/2019 and 01/03/2020 (pre-COVID-19, first period) and between 01/03/2020 and 01/03/2021 (post-COVID-19, second period).

Factors influencing attitudes towards brain drain among nursing students: A path analysis.

Background: Brain drain is the migration of trained professionals and scientists from low and middle-income countries to live and work in better conditions in high-income countries. The brain drain and brain drain intentions of qualified nurses have become a global burning issue for healthcare sustainability in low and middle-income countries. In Türkiye, the idea of brain drain has increased among nurses and nursing students.

The link between cutaneous allodynia and pain/sensitivity in teeth and gums during migraine episodes.

Background: Migraine is one of the most common primary headaches worldwide, while toothache is the most common pain in the orofacial region. The association of migraine pain, and oral pain is unknown. This study aims to investigate the association between migraine and dental and gingival pain with the presence of allodynia.

Clinical and Demographic Characteristics of Treatment Requiring Retinopathy of Prematurity in Big Premature Infants in Turkiye: Report No. 1 (BIG-ROP Study).

Introduction: The aim of the study was to analyse the clinical and demographic features of infants with gestational age (GA) of 32-37 weeks and birth weight (BW) of >1,500 g who developed treatment requiring retinopathy of prematurity (ROP).

Methods: Data on the infants with a GA of 32-37 weeks and BW >1,500 g who developed treatment requiring ROP (TR-ROP) were collected retrospectively from the 33 ROP centres in Turkiye. GA, BW, type of hospital, neonatal intensive care units (NICUs) level, presence of an ophthalmologist and neonatologist in the same hospital, length of stay in NICU, duration of oxygen therapy, comorbidities, type of ROP, and timing for TR-ROP development were analysed.