2 results match your criteria: "Mercer University School of Medicine and Memorial Health University Medical Center[Affiliation]"
Hydrophobic core of the steroidogenic acute regulatory protein for cholesterol transport.
Biochemistry
February 2009
Department of Biomedical Sciences, Mercer University School of Medicine and Memorial Health University Medical Center, Savannah, Georgia 31404, USA.
The steroidogenic acute regulatory protein (StAR), the first family member of START (StAR-related lipid transport) proteins, plays an essential role by facilitating the movement of cholesterol from the outer to inner mitochondrial membrane. Wild-type and mutant StAR binds cholesterol with similar intensity, but only wild-type StAR can transport it to mitochondria. Here, we report that the hydrophobic core is crucial for biological activity of proteins with START domains.
View Article and Find Full Text PDFRecurrent colorectal carcinoma detected by routine cervicovaginal papanicolaou smear testing.
J Low Genit Tract Dis
October 2005
Mercer University School of Medicine and Memorial Health University Medical Center, Department of Obstetrics and Gynecology, Savannah, GA 31404, USA.
Background: We present a case of recurrent colon cancer detected by routine, annual Papanicolaou screening.
Case: A 59-year-old African American woman who had been treated for T2N0M0 (stage II, Dukes A) colon cancer 2 years before to presentation had a Pap smear showing a high-grade squamous intraepithelial lesion with a normal cervical biopsy result. Because of this discrepancy, a loop electrosurgical excision procedure and endocervical curettage were performed and showed atypical glandular cells suspicious for adenocarcinoma.