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J Clin Aesthet Dermatol
February 2021
Drs. Farag, Hammam, El-Swah, and Shehata are with the Dermatology, Andrology and Venereology Department, Faculty of Medicine, Menoufia University in Al Minufya, Egypt.
Melasma is a chronic hypermelanotic disorder that is challenging to treat; no single effective therapeutic agent for it has been discovered. Methimazole, an oral antithyroid drug, has a skin depigmenting effect when used topically. We sought to evaluate the efficacy and safety of methimazole, applied during microneedling sessions and additional topical use in between sessions, for the treatment of melasma.
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