6,771 results match your criteria: "Menorrhagia"
The relationship between menstrual cycle characteristics, premenstrual syndrome prevalence and blood phenylalanine level in women with PKU.
Mol Genet Metab Rep
December 2024
Istanbul University, Faculty of Medicine, Pediatric Nutrition and Metabolism Division, Istanbul, Turkey.
Unlabelled: Phenylketonuria (PKU) results from a deficiency in phenylalanine hydroxylase, catalyzing the conversion of phenylalanine (Phe) to tyrosine. Premenstrual syndrome (PMS) consists of physical, behavioral, and emotional symptoms occurring during the last week of luteal phase. The aim of the study was to determine the incidence of PMS, and document menstrual cycle characteristics of PKU patients to reveal the relationship with blood Phe levels.
View Article and Find Full Text PDFLarge Endometrioma That Triggered a Hypertensive Emergency: A Case Report.
Case Rep Obstet Gynecol
October 2024
Department of Obstetrics & Gynecology, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Article Synopsis
- Endometriosis affects many women of reproductive age, causing symptoms like pelvic pain and infertility, with endometriomas being cystic masses usually located on the ovaries.
- The case study highlights a rare instance of a 25-cm endometrioma in a patient who had not been previously diagnosed with endometriosis, leading to an acute hypertensive emergency.
- The treatment involved minimally invasive surgery to remove the cyst and adhesions, which successfully resolved the patient's condition without complications.
Endometriosis Beyond the Pelvis: A Case of Pancreatic Involvement.
Cureus
September 2024
Internal Medicine, Eastern Virginia Medical School, Norfolk, USA.
Article Synopsis
- Dysmenorrhea, or menstrual pain, is common and often benign, but recurrent episodes may indicate conditions like endometriosis.
- A case study of a 46-year-old woman with frequent hospital visits due to dysmenorrhea revealed she had pancreatitis caused by endometriosis, highlighting the need for accurate diagnosis.
- This report aims to raise awareness about pancreatic endometriosis as a rare cause of pancreatitis, especially in patients experiencing recurrent menstrual pain and unusual symptoms.
Déjà vu all over again: a recurrent flaw in anticoagulant study design.
J Thromb Haemost
October 2024
Division of Hematology, Department of Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Article Synopsis
- The introduction of direct oral anticoagulants (DOACs) since 2010 has significantly changed blood-thinning treatments, shown to be effective and often safer than warfarin for patients of all ages.
- Postmarketing data revealed a higher incidence of heavy menstrual bleeding (HMB) with rivaroxaban, an issue that wasn't evident during clinical trials.
- Current research is exploring Factor XI inhibitors as a new anticoagulant option, but a systematic review found a lack of studies focusing on menstruating individuals and uterine bleeding, indicating a gap in clinical trial designs.
Spontaneous Autoamputation of Adnexa.
CRSLS
October 2024
Department of Obstetrics and Gynecology, University of Illinois College of Medicine, Peoria, Illinois. (Ms. Banoub and Drs. Konrath, Khan, and Elkattah).
Introduction: Acquired ovarian torsion is an uncommon gynecologic emergency that afflicts women of reproductive age and requires correction by surgery. A rare complication of asymptomatic ovarian torsion can be necrosis and autoamputation of the adnexal structures.
Case Description: A 28-year-old nulliparous woman presented with irregular menses since puberty associated with dysmenorrhea, menorrhagia, and nausea, and that did not improve with trials of oral hormone therapy.
A rare case of a 5-year-old girl with Klippel-Trénaunay syndrome and a bleeding focal vulvar hemangioma in Uganda.
Clin Case Rep
October 2024
Head of Department, Dermatology MUST Mbarara Uganda.
Article Synopsis
- * The case involved a 5-year-old girl exhibiting common KTS traits alongside a rare bleeding hemangioma, requiring specific treatments like compression bandaging and timolol.
- * Continuous monitoring of female patients with KTS is crucial to manage potential complications that may arise during adolescence and pregnancy.
A Multicenter Retrospective Cohort Study Assessing the Incidence of Anemia in Patients Associated With Uterine Fibroids.
Cureus
September 2024
Obstetrics and Gynecology, Assisted Reproduction in Gynecology Center, London, GBR.
Article Synopsis
- Uterine fibroids are benign tumors that often lead to symptoms like heavy menstrual bleeding (menorrhagia), which can affect women’s quality of life, particularly in premenopausal women.
- This study analyzed the relationship between different types of uterine fibroids and the incidence of anemia in patients diagnosed with fibroids between 2016 and 2022.
- Findings revealed that 75% of women with submucosal fibroids experienced anemia, while subserosal fibroids were linked to the lowest risk, though all fibroid types showed no significant differences in anemia severity.
The effect of psychological stress on the menstrual cycle among medical students.
J Pak Med Assoc
October 2024
Department of Family and Community Medicine, Mustansiriyah University, Baghdad, Iraq.
Article Synopsis
- - The study aimed to evaluate the prevalence of menstrual abnormalities among female medical students in Baghdad and to determine how these abnormalities relate to their stress levels.
- - Conducted between May 18 and May 28, 2021, the research involved 397 participants and used an online questionnaire to gather data on demographics, menstrual history, and psychological stress through the Perceived Stress Scale-10.
- - Results showed that a high percentage experienced dysmenorrhea and premenstrual symptoms, with a significant link found between higher stress levels and these menstrual issues, indicating that stress may exacerbate menstrual abnormalities.
Utilizing acute normovolemic hemodilution for blood conservation in myomectomy for Jehovah's Witnesses: A case report.
SAGE Open Med Case Rep
October 2024
Department of Obstetrics and Gynaecology, Irrua Specialist Teaching Hospital, Irrua, Nigeria.
Article Synopsis
- Myomectomy for Jehovah's Witnesses poses challenges due to their refusal of blood transfusions, requiring careful surgical planning.
- A patient's successful procedure involved a multidisciplinary effort to conserve blood, utilizing acute normovolemic hemodilution (ANH) and precise surgical techniques.
- The case emphasizes the need for healthcare providers to respect patients' beliefs while demonstrating ANH as an effective strategy for managing blood loss in complex surgeries.
Frequency of Anemia/IDA and Associated Risk Factors Among Working Women of a Medical Center in Tehran, Iran: A Cross-Sectional Study.
Indian J Community Med
August 2024
Cardiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The study investigated the prevalence and risk factors of anemia in employed women at a medical center versus unemployed women from a charity center, defining anemia and iron deficiency by specific hemoglobin and serum levels.
- Among 651 participants, 60.7% were found to have anemia or iron deficiency anemia (IDA), with younger age and menorrhagia identified as significant risk factors.
- The results highlighted a notable difference in anemia prevalence, with 60.7% of hospital staff affected compared to 43.1% of charity center women, suggesting employment impacts anemia rates.
Advances in Adenomyosis Treatment: High-Intensity Focused Ultrasound, Percutaneous Microwave Therapy, and Radiofrequency Ablation.
J Clin Med
September 2024
Department of Obstetrics and Gynecology, University Hospital of Fribourg, 1708 Fribourg, Switzerland.
Article Synopsis
- Adenomyosis is a painful condition affecting women that can lead to symptoms like severe menstrual pain, heavy bleeding, and infertility, and new thermal ablation techniques present minimally invasive treatment options.
- Techniques like high-intensity focused ultrasound, microwave ablation, and radiofrequency ablation are found to effectively reduce symptoms and uterine size without compromising fertility or requiring lengthy hospital stays.
- Despite promising results regarding safety and effectiveness, further research is needed to compare these new treatments to traditional therapies to inform future medical decisions.
Effectiveness of the use of intravenous tranexamic acid and pericervical tourniquet in decreasing peri-operative blood loss following open abdominal myomectomy:A randomized controlled trial.
Niger Med J
September 2024
Department of Obstetrics and Gynaecology, Barau Dikko Teaching Hospital, Kaduna, Nigeria.
Article Synopsis
- - Uterine fibroids are the most common gynecological tumors, affecting 20-50% of women over 30, often leading to menorrhagia (heavy bleeding) and requiring treatment options like open abdominal myomectomy, which carries risks of significant blood loss and transfusions.
- - A study at Barau Dikko Teaching Hospital assessed the effectiveness of intravenous tranexamic acid in reducing blood loss during open abdominal myomectomy, involving 36 patients randomly assigned to receive either tranexamic acid or a placebo alongside a peri-cervical tourniquet.
- - Results indicated that women receiving tranexamic acid experienced less blood loss (mean of 947.65 ml) compared to the placebo group
A Comparative Analysis of the Bleeding Profile and Quality of Life Among Women With Hemophilia Genotype Compared to Other Bleeding Disorders.
Cureus
September 2024
Department of Pathology, Post Graduate Institute of Child Health, Noida, IND.
Article Synopsis
- * This study compares the bleeding profiles and quality of life (QOL) of women and girls with hemophilia to those with VWD and rare bleeding disorders, using the ISTH Bleeding Assessment Tool and the EuroQOL questionnaire.
- * Initial findings showed that 80 participants were enrolled, with a median age of 35 for hemophilia carriers and 15.5 for those with diagnosed bleeding disorders, revealing a significant family history of bleeding disorders in both groups.
Article Synopsis
- - This study, conducted from April 2021 to October 2022, focused on the potential impact of COVID-19 vaccines on menstrual cycles in women who received three doses of the vaccine.
- - Out of 308 participants, 22 women (7.1%) reported abnormal menstrual changes after vaccination, with metrorrhagia being the most common issue observed in nearly half of these cases.
- - A significant percentage (59%) of those who reported disturbances experienced persistent symptoms, and some participants also contracted COVID-19 after showing menstrual disorders, suggesting that the virus might contribute to these changes alongside vaccination effects.
Association between coagulation indicators and menorrhagia among women in Kenya.
Afr J Lab Med
September 2024
Department of Biomedical Sciences, Faculty of Public Health and Community Development, Maseno University, Maseno, Kenya.
Article Synopsis
- Many women in Western Kenya have a problem called menorrhagia, which means they bleed a lot during their periods.
- The study looked at whether there are differences in blood clotting among women who have this issue compared to those who don’t.
- The results showed that women with menorrhagia are more likely to have a family history of bleeding problems and higher blood test levels related to clotting.
The WeThrive App and Its Impact on Adolescents Who Menstruate: Qualitative Study.
JMIR Form Res
October 2024
Division of Hematology/Oncology, Department of Pediatrics, Izaak Walton Killam Health Centre, Halifax, NS, Canada.
Background: Heavy menstrual bleeding (HMB) affects up to 37% of adolescents. Without recognition, HMB can lead to other medical conditions resulting in diminished health-related quality of life. WeThrive, a new mobile health (mHealth) app, implements the pictorial bleeding assessment chart to identify HMB, and the adolescent Menstrual Bleeding Questionnaire to measure the effects of HMB on adolescents' health-related quality of life.
View Article and Find Full Text PDFReal-world efficacy and safety of intravenous ferric carboxymaltose for the management of iron deficiency anaemia in Malaysia: A single centre cohort study.
Med J Malaysia
September 2024
Bukit Tinggi Medical Centre, Bandar Bukit Tinggi 1, Klang, Selangor, Malaysia.
Introduction: Up to 24.2% Malaysians are estimated to be affected by anaemia. Iron deficiency is the most common nutritional deficiency leading to anaemia.
View Article and Find Full Text PDFImprovement of laboratory markers of anaemia in the treatment of heavy menstrual bleeding with a 19.5-mg intrauterine device: a pilot study.
Eur J Contracept Reprod Health Care
December 2024
Department of Obstetrics and Gynaecology, University of Campinas (UNICAMP), Faculty of Medical Sciences, Campinas, SP, Brazil.
Objectives: To evaluate improvements in laboratory markers of anaemia (haemoglobin, haematocrit, serum iron, and ferritin) in women with subjective heavy menstrual bleeding (HMB) treated with the levonorgestrel 19.5-mg intrauterine device.
Materials And Methods: We conducted a pilot study at the Department of Obstetrics and Gynaecology, University of Campinas, Faculty of Medical Sciences, Campinas, SP, Brazil.
The clinical diversity of primary hypothyroidism presenting as a spontaneous ovarian hyperstimulation syndrome.
Endocrinol Diabetes Metab Case Rep
July 2024
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India.
Article Synopsis
- * The study reviewed five patients with untreated hypothyroidism who showed complications like multicystic ovaries and delayed bone age, with some experiencing severe symptoms like menorrhagia and ovarian torsion.
- * Early detection and a collaborative approach between gynecology and endocrinology are crucial for managing spontaneous OHSS, which can be life-threatening but is easy to treat with proper care.
The Correlation of Hysteroscopy and Histopathology in Evaluating Abnormal Uterine Bleeding: Observations From a Tertiary Care Center.
Cureus
August 2024
Obstetrics and Gynecology, Dr. D. Y. Patil Medical College, Hospital, and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Background: Abnormal uterine bleeding (AUB) is an important clinical entity, and its subtype, heavy menstrual bleeding (HMB), affects 14%-25% of women of reproductive age, potentially impairing their physical, emotional, social, and material quality of life. However, in addition to prior studies that supported the efficacy of hysteroscopy in identifying AUB, this study determined the overall pattern of abnormalities in AUB and correlated the diagnosis through hysteroscopy and histopathology. Additionally, a comparison of ultrasonography was done in this study.
View Article and Find Full Text PDFEstrogen receptor alpha mediated repression of PRICKLE1 destabilizes REST and promotes uterine fibroid pathogenesis.
bioRxiv
September 2024
Department of Cell Biology and Physiology, Center for Reproductive Sciences, Institute for Reproduction and Developmental Sciences, University of Kansas Medical Center, Kansas City, KS.
Article Synopsis
- Uterine fibroids are non-cancerous growths in women's reproductive muscles, affecting over 75% of women and causing issues like pain and heavy periods.
- Researchers found that a protein called PRICKLE1 is lower in these fibroids, and its loss is linked to changes in another protein, REST, which can lead to tumor development.
- Estrogen, a hormone, seems to lower PRICKLE1 and REST levels; understanding this connection could help in finding new ways to treat fibroids.
Retinal vein occlusion coinciding with paracentral acute middle maculopathy in patient with menorrhagia causing life-threatening anemia.
Int J Ophthalmol
September 2024
Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan, China.
Submucosal cystic adenomyosis: a report of five cases and review of the literature.
BMC Womens Health
September 2024
Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, No.18, Daoshan Rd., Gulou Dist, Fuzhou City, Fujian Province, China.
Aim: To investigate the clinical characteristics, diagnosis, and clinical treatment of submucosal cystic adenomyosis.
Methods: The clinical data of five cases of patients with submucosal cystic adenomyosis in our hospital from January 2020 to June 2023 were retrospectively analyzed.
Results: The average age of the patients was 37.
Tranexamic Acid in Mohs Micrographic Surgery: A Systematic Review.
Dermatol Surg
January 2025
Division of Dermatology, Washington University in St. Louis, Saint Louis, Missouri.
Background: Tranexamic acid (TXA) is an antifibrinolytic that has historically been used to treat menorrhagia and bleeding disorders. Exploration of its use in procedures has grown, and it has shown promise in its ability to achieve hemostasis with low risk to patients. Analysis of its use in Mohs micrographic surgery (MMS) is warranted due to its potential superiority to traditional methods of achieving hemostasis (direct pressure, electrocoagulation, and sutures).
View Article and Find Full Text PDFBiological Abnormalities of Hemostasis in Patients with Epistaxis or Menorrhagia in Yaoundé, Cameroon.
Adv Hematol
August 2024
Faculty of Medicine and Biomedical Sciences University of Yaoundé I, Yaoundé, Cameroon.
Article Synopsis
- In Cameroon, it's hard to find and understand bleeding problems, especially minor ones like epistaxis (nosebleeds) and menorrhagia (heavy periods).
- A study looked at 60 patients to see what's happening with their blood and why they bleed.
- The results showed that many patients had issues with their blood that could cause bleeding, with the most common problems being low levels of a special protein and longer bleeding times.