618 results match your criteria: "Melanonychia"
Celebrating Diversity: Unveiling the Characteristics of Nail Psoriasis and Nail Lichen Planus in 30 Patients With Skin of Color.
Dermatol Pract Concept
October 2024
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Introduction: Dermatological conditions affecting the nails can manifest differently in individuals with distinct skin tones. This often leads to difficulty in the recognition of nail diseases, especially in people with skin of color (SoC), who are not well represented in the literature.
Objectives: Our aim was to provide dermatologists with useful clues for prompt recognition and diagnosis of nail psoriasis (NPso) and nail lichen planus (NLP) in people with SoC.
Two Cases of Fungal Melanonychia.
Acta Derm Venereol
November 2024
Department of Dermatology, Tokyo Metropolitan Police Hospital, Tokyo, Japan.
Epidemiologic, Clinical and Mycological Profile of Onychomycosis in the Hospital Setting in Benin.
Dermatol Res Pract
October 2024
Service de Dermatologie-Vénérologie, Centre National Hospitalier et Universitaire Hubert Koutoukou Maga de Cotonou, Faculté des Sciences de La Santé-Université d'Abomey-Calavi, Cotonou, Benin.
Article Synopsis
- A total of 389 patients were seen, with 301 suspected of onychomycosis, but only 128 were confirmed through mycological testing, resulting in a 32.90% frequency of onychomycosis among nail disorders.
- The study found that patients were mostly middle-aged women, with aesthetic concerns being the primary reason for consultation; the predominant fungi isolated were yeasts, while misunderstandings about
Biopsy-proven diagnoses associated with monodactylous longitudinal nail plate change in a diverse patient population: A retrospective cross-sectional study.
JAAD Int
December 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.
Pediatric Nail Disorders.
Skin Appendage Disord
October 2024
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Article Synopsis
- * Congenital nail disorders can be non-syndromic (with isolated anomalies) or syndromic (part of larger syndromes), requiring thorough evaluation for related systemic issues.
- * Acquired nail conditions can arise from trauma or infections and should be taken seriously; melanonychia, though rare in kids, needs careful monitoring for potential malignancy.
Nearly complete hair re-pigmentation in an older patient treated with hydroxyurea for essential thrombocytosis.
J Oncol Pharm Pract
September 2024
Lucy Curci Cancer Center, Eisenhower Health, Rancho Mirage, CA, USA.
Article Synopsis
- * A case study details a 77-year-old woman with essential thrombocytosis who, after 20 weeks on low-dose hydroxyurea, experienced an unexpected change in hair color from gray to dark brown, along with other skin changes.
- * The patient's side effect was monitored without intervention since she was pleased with the new hair color, suggesting that hydroxyurea may have both therapeutic benefits and unexpected aesthetic effects due to melanocyte activation.
Customized Dermal Curette: An Alternative and Effective Shaving Tool in Nail Surgery.
Cutis
August 2024
Department of Dermatology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Surgical excision of the pigmented nail matrix followed by histopathologic examination is a common procedure aimed at managing longitudinal melanonychia (LM). In some cases, use of a standard scalpel can pose challenges, particularly if the width of the pigmented matrix lesion is narrow. We explore an alternative and effective tool-the customized dermal curette.
View Article and Find Full Text PDFSubungual melanoma: molecular analysis of 31 cases from early stage to invasive melanoma.
Histopathology
January 2025
Institute for Research on Cancer and Aging of Nice (IRCAN) CNRS UMR 7284/INSERM U1081, University of Cote d'Azur (UCA), Nice University Hospital, Nice, France.
Article Synopsis
- * ACGH showed promising results, identifying oncogene amplifications in the majority of invasive SUM cases and exhibited significantly higher sensitivity (93%) when melanocyte counts (MC) were greater than 45/mm.
- * The findings suggest that aCGH is a valuable tool for differentiating between malignant and benign lesions, and should be utilized especially when MC is above the specified threshold, while NGS was found to be less informative.
Impact of Chemotherapy-Induced Nail Changes on Quality of Life: A Cross-Sectional Study from a Tertiary Care Centre.
Indian J Dermatol
June 2024
From the Department of Dermatology Venereology and Leprosy, Sardar Patel Medical College, Bikaner, Rajasthan, India.
Article Synopsis
- Chemotherapy can improve survival rates in cancer patients but often leads to adverse effects, particularly nail changes, that impact quality of life (QoL) significantly.
- A study involving 188 patients on chemotherapy found that nail changes were associated with lower QoL scores, especially affecting younger patients and women more severely.
- The research emphasizes the need for healthcare providers to counsel patients about potential nail changes during treatment to help manage psychological and social issues related to these cosmetic concerns.
Transverse Melanonychia Following Paclitaxel Infusions.
J Cutan Med Surg
August 2024
Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.
Ethical considerations for dermatologists providing unsolicited advice about malignant nail conditions.
J Am Acad Dermatol
July 2024
Department of Dermatology, Weill Cornell Medicine, New York, New York. Electronic address:
Dermoscopic Nail Changes in Psoriasis, Lichen Planus, and Lichen Striatus.
Skin Appendage Disord
August 2024
Private Dermatology Practice, Lugano/Bellinzona, Switzerland.
Article Synopsis
- Onychoscopy is a non-invasive technique used to better diagnose nail disorders like nail psoriasis and lichen planus, providing detailed visual insights beyond a standard clinical examination.
- In nail psoriasis, key onychoscopic features include pitting, onycholysis with a red border, and specific patterns like salmon patches, while nail lichen planus shows signs like onychorrhexis and longitudinal melanonychia.
- There is limited literature on the use of onychoscopy for nail lichen striatus, and the features observed can vary between fingernails and toenails.
Clinical and dermoscopic features of onychomatricoma in Korean patients.
Australas J Dermatol
August 2024
Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Fungal Melanonychia: A Systematic Review.
Microorganisms
May 2024
Ibero-Latin American College of Dermatology (CILAD), Buenos Aires C1091, Argentina.
Article Synopsis
- * The study found that the majority of affected individuals were men, with a notable prevalence in Turkey, and common factors contributing to the condition included nail trauma and outdoor activities.
- * Clinical presentations varied, with 45% having a single affected nail and diverse melanonychia types observed, indicating a complex differential diagnosis for this uncommon variant of onychomycosis.
Managing longitudinal melanonychia.
Hand Surg Rehabil
April 2024
Institut de la Main et du Membre Supérieur, Marseille, France.
Article Synopsis
- Longitudinal melanonychia (LM) is a pigmented nail band caused by melanin overproduction from melanocytes in the nail matrix, often benign but potentially indicating subungual melanoma.
- Diagnosis of melanoma involves assessing biographical, clinical, and dermoscopic criteria, but a definitive diagnosis requires a matrix biopsy for pathological examination.
- Effective biopsy techniques should minimize nail dystrophy while allowing for complete lesion removal; minor lesions up to 3 mm can be removed safely, while larger ones may require different biopsy methods or complete nail unit resection if melanoma is strongly suspected.
A Misdiagnosed Case of Malignant Melanoma in an Infected Nail: A Case Report.
Cureus
May 2024
Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Article Synopsis
- * Accurate diagnosis is challenging due to its similarity to other pigmented conditions, requiring a thorough histopathological evaluation for resolution.
- * Early detection is crucial for effective treatment; therefore, combining clinical assessment, dermoscopy, and histopathological analysis is essential to prevent misdiagnosis.
Update on Squamous Cell Carcinoma of the Nail Unit: An Human Papillomavirus-Associated Condition.
Skin Appendage Disord
June 2024
Philip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Article Synopsis
- Squamous cell carcinoma (SCC) and Bowen's disease are common skin cancers mostly found in men over 50, primarily affecting the fingers, with high-risk HPV infection playing a significant role in their development.
- The review discusses how HPV contributes to the onset of nail unit SCC, including how it spreads, along with the clinical characteristics of these HPV-associated cases.
- It also highlights advances in treating nail unit SCC, emphasizing that HPV vaccination could be a promising non-surgical option for managing these cancers.
Various Free Flap Reconstruction Techniques after Hand and Foot Melanonychia Ablation: A Case Series.
J Clin Med
May 2024
Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul 13620, Republic of Korea.
Article Synopsis
- - The management of melanonychia, which can resemble nail melanoma, is debated, and surgical removal of the entire lesion is often necessary for accurate diagnosis and treatment.
- - Between 2020 and 2022, eleven patients underwent surgical procedures that involved total nail bed removal followed by immediate reconstruction using fasciocutaneous free flaps.
- - Histological analysis confirmed benign lesions in all cases post-surgery, with no complications aside from one instance of partial necrosis that healed, and there were no recurrences or nail regrowth observed during follow-up.
Role of tangential biopsy in the diagnosis of nail psoriasis.
An Bras Dermatol
August 2024
Dermatology Service, Hospital do Servidor Público Municipal de São Paulo, São Paulo, SP, Brazil.
Background: Histopathology can be crucial for diagnosis of inflammatory nail diseases. Longitudinal excision and punch biopsies are the most used techniques to obtain the tissue sample. However, there is a low clinical-histopathological correlation, besides the risk of nail dystrophy.
View Article and Find Full Text PDFLongitudinal melanonychia caused by Cladophialophora boppii: Dermoscopic findings prompting the suspicion of fungal melanonychia.
J Dermatol
October 2024
Medical Mycology Research Center, Chiba University, Chiba, Japan.
A case of Bowen's disease of the nails in siblings: detection of the same human papillomavirus type 56.
Int J Dermatol
November 2024
Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Longitudinal melanonychia.
Cutis
March 2024
Department of Urban Health and Population Science, Center for Urban Bioethics, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Multiple-Digit Pigmented Bowen's Disease Induced by Human Papillomavirus in an Immunocompetent Child.
Skin Appendage Disord
April 2024
Dermatology Department, Hospital do Servidor Público Municipal de São Paulo, São Paulo, Brazil.
Introduction: Bowen's disease is a squamous cell carcinoma in situ, the most common malignancy of the nail unit. Presenting more frequently in the fingernails, common risk factors include ionizing radiation, oral exposure to arsenic or pesticides, dyskeratosis congenita, and quite commonly diverse subtypes of HPV. We report the first case of multiple periungual pigmented Bowen's disease in a pediatric patient.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the prevalence of malignant nail conditions in pediatric patients with melanonychia, hypothesizing a low rate of melanoma in those undergoing nail bed biopsies.
- Researchers reviewed medical data from 54 patients under 18 years old who had nail bed biopsies between 2007 and 2022, analyzing demographics and pathology results.
- Findings revealed no instances of malignant melanoma, with the most common diagnoses being benign conditions, and the only significant risk factor linked to concerning pathology was the year of biopsy performed.