The role of the G20 economies in global health.

The Meetings of Health Ministers of the Group of Twenty (G20) that started at the G20 Summit in Berlin, Germany in 2017 have provided a platform for the discussion of global health matters such as antimicrobial resistance (AMR), public health emergencies, and universal health coverage. Similar issues are also discussed at meetings of the G7 and the World Health Assembly (WHA). This article will examine recent data to explore the characteristics of the G20 and its potential for improving health outcomes.

Solar Radiation Exposure Has Diurnal Effects on Thermoregulatory Responses During High-Intensity Exercise in the Heat Outdoors.

Otani, H, Goto, T, Goto, H, Hosokawa, Y, and Shirato, M. Solar radiation exposure has diurnal effects on thermoregulatory responses during high-intensity exercise in the heat outdoors. J Strength Cond Res 33(10): 2608-2615, 2019-This study investigated the diurnal effects of variations in solar radiation associated with changing solar elevation angle on thermoregulatory responses during high-intensity exercise in the heat outdoors.

Preschool children's eating and sleeping habits: late rising and brunch on weekends is related to several physical and mental symptoms.

Objective: As the relationships of sleep-wake schedule and mealtime with children's behaviors have not often been studied together, we investigated the relationships of these lifestyles variables with preschool children's well-being.

Methods: Using a network survey, we investigated several lifestyle variables of 1000 families with preschool children.

Results: Our previous articles reported that preschool children's bedtime was delayed by the compulsory nap routine in Japanese nursery schools.

Nicotianamine Synthesis by Is Important for Mitigating Iron Excess Stress in Rice.

Iron (Fe) toxicity in plants causes tissue damage and cellular homeostasis disorders, thereby affecting plant growth and development. Nicotianamine (NA) is a ubiquitous chelator of metal cations and is responsible for metal homeostasis. Rice has three NA synthase () genes, of which the expression of and but not of is strongly induced in response to Fe deficiency.

Shenkang injection, a modern preparation of Chinese patent medicine, diminishes tubulointerstitial fibrosis in obstructive nephropathy via targeting pericyte-myofibroblast transition.

Shenkang injection (SKI), a modern preparation of Chinese patent medicine, has been widely applied to clinical therapy in the chronic renal failure patients. However, it remains elusive whether SKI can ameliorate tubulointerstitial fibrosis (TIF) . Recently, pericyte-myofibroblast transition (PMT) plays an important role in the pathogenesis of TIF in obstructive nephropathy (ON).

Implementation and Evaluation of a Wide-Range Human-Sensing System Based on Cooperating Multiple Range Image Sensors.

A museum is an important place for science education for children. The learning method in the museum is reading exhibits and explanations. Museums are investing efforts to quantify interests using questionnaires and sensors to improve their exhibitions and explanations.

Huangkui capsule alleviates renal tubular epithelial-mesenchymal transition in diabetic nephropathy via inhibiting NLRP3 inflammasome activation and TLR4/NF-κB signaling.

Background: Huangkui capsule (HKC), an anti-inflammatory Chinese modern patent medicine, has been now widely applied to the clinical therapy of diabetic nephropathy (DN). However, the overall therapeutic mechanisms in vivo are still unclear. Renal tubular epithelial-to-mesenchymal transition (EMT) is one of the major pathogenesis of renal interstitial fibrosis in DN.

Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy.

The kidney is a typical organ undergoing age and injury. Hyperoside is reported to be useful for preventing aging induced by D-galactose (D-gal). However, therapeutic mechanisms remain unclear.

Iron transport and its regulation in plants.

Iron is an essential element for plants as well as other organisms, functioning in various cellular processes, including respiration, chlorophyll biosynthesis, and photosynthesis. Plants take up iron from soil in which iron solubility is extremely low especially under aerobic conditions at high-pH range. Therefore, plants have evolved efficient iron-uptake mechanisms.

Structural effects of ditopic azoprobe-cyclodextrin complexes on the selectivity of guest-induced supramolecular chirality.

Benzo-15-crown-5 and dipicolylamine are contained as the binding sites in a ditopic azoprobe (15C5-Azo-n-dpa). However, the selectivities of guest-induced supramolecular chirality for cations and anions were dramatically altered by a slight change in the spacer length of (15C5-Azo-n-dpa)2-γ-CyD complexes in water.

Violence Against Women and Children Following the 2011 Great East Japan Disaster: Making the Invisible Visible Through Research.

This study reports on 82 unduplicated cases of violence against women and children after the Great East Japan Disaster of March 2011. Data were collected using a structured questionnaire from informants who worked with the disaster-affected populations. In addition to domestic violence, reported cases involved sexual assault and unwanted sexual contact, including quid pro quo assault perpetrated by nonintimates.

Deciding for others as a neutral party recruits risk-neutral perspective-taking: Model-based behavioral and fMRI experiments.

Risky decision making for others is ubiquitous in our societies. Whereas financial decision making for oneself induces strong concern about the worst outcome (maximin concern) as well as the expected value, behavioral and neural characteristics of decision making for others are less well understood. We conducted behavioral and functional magnetic resonance imaging (fMRI) experiments to examine the neurocognitive underpinnings of risky decisions for an anonymous other, using decisions for self as a benchmark.

Relational mobility predicts social behaviors in 39 countries and is tied to historical farming and threat.

Biologists and social scientists have long tried to understand why some societies have more fluid and open interpersonal relationships and how those differences influence culture. This study measures relational mobility, a socioecological variable quantifying voluntary (high relational mobility) vs. fixed (low relational mobility) interpersonal relationships.

Inhibition of Akt/mTOR/p70S6K Signaling Activity With Huangkui Capsule Alleviates the Early Glomerular Pathological Changes in Diabetic Nephropathy.

Huangkui capsule (HKC), a Chinese modern patent medicine extracted from (L.) medic, has been widely applied to clinical therapy in the early diabetic nephropathy (DN) patients. However, it remains elusive whether HKC can ameliorate the inchoate glomerular injuries in hyperglycemia.

Ring-to-Cage Structural Conversion via Template Effect in a Gold(I) Metallosupramolecular System.

A unique example of a ring-to-cage structural conversion in a multinuclear gold(I) coordination system with d-penicillamine (d-H pen) is reported. The reaction of [Au Cl (dppe)] (dppe=1,2-bis(diphenylphosphino)ethane) with d-H pen in a 1:1 ratio gave [Au (dppe) (d-pen) ] ([1]), in which two [Au (dppe)] units are linked by two d-pen S atoms in a cyclic form so as to have two bidentate-N,O coordination arms. The subsequent reaction of [1] with Cu(OTf) afforded [Au Cu(dppe) (d-pen) ] ([2] ), in which a Cu ion is chelated by the two coordination arms in [1] to form an Au Cu bicyclic metallocage.

A single-arm pilot study of guided self-help treatment based cognitive behavioral therapy for bulimia nervosa in Japanese clinical settings.

Objective: Guided self-help treatments based on cognitive behavioral therapy (CBT-GSH) are regarded as a first-line effective treatment for bulimia nervosa (BN). With limited application for CBT-GSH in Japanese clinical settings, we conducted a single arm pilot study in order to confirm the acceptability and availability of CBT-GSH in Japan.

Results: 25 women with BN received 16-20 sessions of face-to-face CBT-GSH.

The Nicotianamine Synthase Gene Is a Useful Candidate for Improving the Nutritional Qualities and Fe-Deficiency Tolerance of Various Crops.

With the global population predicted to grow by at least 25% by the year 2050, the sustainable production of nutritious foods will be necessary for human health and the environment. Iron (Fe) is an essential nutrient for both plants and humans. Fe is poorly soluble, especially at high pH levels, at which it is difficult for living organisms to accumulate sufficient Fe.

Diurnal effects of prior heat stress exposure on sprint and endurance exercise capacity in the heat.

Active individuals often perform exercises in the heat following heat stress exposure (HSE) regardless of the time-of-day and its variation in body temperature. However, there is no information concerning the diurnal effects of a rise in body temperature after HSE on subsequent exercise performance in a hot environnment. This study therefore investigated the diurnal effects of prior HSE on both sprint and endurance exercise capacity in the heat.

Development of Dipicolylamine-Modified Cyclodextrins for the Design of Selective Guest-Responsive Receptors for ATP.

The construction of supramolecular recognition systems based on specific host-guest interactions has been studied in order to design selective chemical sensors. In this study, guest-responsive receptors for ATP have been designed with cyclodextrins (CyDs) as a basic prototype of the turn-on type fluorescent indicator. We synthesized dipicolylamine (DPA)-modified CyD-Cu complexes (, , and ), and evaluated their recognition capabilities toward phosphoric acid derivatives in water.

Core factors promoting a continuum of care for maternal, newborn, and child health in Japan.

Providing a continuum of care (CoC) is important strategy for improving maternal, newborn, and child health (MNCH). Japan's current very low maternal and infant mortality rates suggest that its CoC for MNCH is good. In this paper, we attempt to clarify how CoC and low mortality rates are being maintained in Japan, by examining the entire MNCH service provision system.

Passion, Relational Mobility, and Proof of Commitment: A Comparative Socio-Ecological Analysis of an Adaptive Emotion in a Sexual Market.

Although monogamy, the exclusive bonding with a specific partner, is one characteristic of modern human mating, long-term romantic relationships inherently possess the commitment problem, which is the conflict between maintaining a relationship with a certain partner and seeking attractive alternatives. Frank has argued that love and passion help solve this problem because they make individuals commit voluntarily to the relationship, leading the other party to also be committed with less concern over being cheated on or rejected. Combining this idea with the comparative socio-ecological approach, we hypothesize that passion will be more pronounced in social environments in which people have greater freedom to choose and replace their partners (i.