867 results match your criteria: "Meigs Syndrome"

Pseudo-pseudo Meigs' syndrome (PPMS), also known as Tjalma syndrome, is an exceptionally rare condition marked by pleural effusion, ascites, and elevated CA-125 levels, usually in the context of systemic lupus erythematosus (SLE) without any associated ovarian tumors. We report the case of a 40-year-old woman who presented with a four-month history of fatigue, nausea, weight loss, abdominal pain, and pleural effusion. Initial diagnostic workup revealed ascites, elevated CA-125 levels, and pleural effusions, with no evidence of malignancy.

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Introduction: Systemic lupus erythematosus is a chronic inflammatory disease affecting women, causing gastrointestinal issues like acute pancreatitis, esophagitis, and protein-losing enteropathy. Protein loss is uncommon, but a case study shows protein-losing enteropathy as a first sign.

Importance: Protein-losing enteropathy (PLE) is a rare gastrointestinal manifestation of SLE, often seen years before diagnosis.

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Meigs syndrome after treatment for catamenial pneumothorax.

Gen Thorac Cardiovasc Surg Cases

November 2023

Department of Surgery, Imamitsu Homecare Clinic, 1-9-10 Imamitsu, Wakamatsu-Ku, Kitakyushu, 808-0071, Japan.

Article Synopsis
  • Catamenial pneumothorax (CP) is a rare condition affecting women, characterized by a collapsed lung associated with menstrual cycles, while Meigs syndrome (MS) involves benign ovarian tumors causing pleural effusion and ascites, and its exact causes are not well understood.
  • A 40-year-old Japanese woman was diagnosed with CP after experiencing dyspnea and undergoing surgery that revealed diaphragmatic foramens.
  • Ten years later, the same patient presented with chest pain and imaging showed signs of MS, leading to surgery that resolved her symptoms, highlighting the rare occurrence of both conditions in one patient and suggesting links between them.
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  • - The case report discusses a postpartum woman suffering from pseudo-Meigs' syndrome (PMS) characterized by symptoms like abdominal pain, significant ascites, and hypercoagulation.
  • - Treatment with emergency anticoagulation led to improvements, such as the resolution of ascites and abdominal pain, despite the presence of a large degenerating uterine fibroid.
  • - Pathological analysis post-surgery confirmed the diagnosis, and ongoing research is recommended to explore the link between hypercoagulable states and PMS in pregnant patients.
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  • Krukenberg tumor is a rare type of ovarian cancer that often shows up with symptoms like abdominal pain and swelling, commonly due to both ovaries being affected.
  • The case study discusses a 39-year-old woman who experienced unusual symptoms like abdominal distension and shortness of breath, leading to the discovery of the tumor.
  • The tumor was confirmed to be signet ring cell carcinoma, and it was associated with Pseudo-Meigs' syndrome, highlighting the importance for doctors to consider this syndrome in similar cases for potential effective treatment.
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  • - Extragenital endometriosis is rare and often diagnosed late, resulting in complications and repeated hospital visits.
  • - The case presented involves a 37-year-old African American woman with thoracic endometriosis, who experienced worsening shortness of breath for two weeks.
  • - Initial concerns for her diagnosis included ovarian cancer and Meig's syndrome, which share similar symptoms, complicating the assessment.
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  • Pseudo-Meigs syndrome involves the disappearance of pleural effusion and ascites after the removal of a pelvic tumor, whether benign or malignant.
  • A case study highlights a 48-year-old woman who experienced shortness of breath and abdominal distention due to a right-sided pleural effusion and ascites, later linked to bilateral ovarian malignancy.
  • The tumor was identified as serous adenocarcinoma, which was surgically removed, leading to the resolution of her symptoms, an occurrence not previously documented in medical literature.
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Pseudo-Meigs syndrome caused by a rapidly enlarging hydropic leiomyoma with elevated CA125 levels mimicking ovarian malignancy: a case report and literature review.

BMC Womens Health

August 2024

Department of Pathology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

Article Synopsis
  • Pseudo-Meigs syndrome is a rare condition featuring fluid build-up in the chest and abdomen due to pelvic masses, and can show elevated CA125 levels, often misinterpreted as cancer.
  • Hydropic leiomyoma (HLM), a unique form of uterine fibroid, may grow rapidly and cause similar symptoms, complicating diagnosis.
  • A case study of a 45-year-old woman diagnosed with HLM instead of cancer showcases how accurate diagnosis led to successful treatment, with significant improvements post-surgery and no recurrence after two years.
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  • * Patients displayed symptoms like high CA-125 levels and significant fluid buildup in the abdomen and lungs, which are usually linked to ovarian cancer but can occur in non-cancerous conditions like SLE.
  • * The review of literature on similar cases highlights the importance of recognizing PPMS in SLE patients who experience unexplained abdominal and pleural fluid accumulation.
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  • Pelvic tumors, though rare, can lead to pleural effusion, as illustrated by a case of Meigs syndrome in a woman in her 60s with recurrent right-sided pleural effusion, cough, and shortness of breath.
  • Initial tests, including thoracentesis and pleuroscopy, showed inflammatory changes and negative malignancy results, but elevated cancer antigen 125 levels raised suspicion for cancer.
  • A CT scan identified a large left ovarian tumor and a uterine mass; subsequent surgery successfully removed them, resulting in no further pleural effusions post-operation.
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Article Synopsis
  • The condition known as pseudo-pseudo Meigs' syndrome (PPMS) occurs in systemic lupus erythematosus (SLE) patients and is characterized by ascites, pleural effusion, and elevated CA-125 levels without any ovarian cancer.
  • A 33-year-old female patient was diagnosed with SLE after experiencing persistent pleural effusion and new onset massive ascites alongside increased CA-125 levels, which led to a renal biopsy revealing class-V lupus nephritis.
  • Treatment with immunosuppressants resulted in significant improvement of SLE symptoms and PPMS components, including the ascites and pleural effusion, without the necessity for diuretics, highlighting the importance of thorough evaluation and treatment in such
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A Case Report of Meigs' Syndrome Caused by Ovarian Fibrothecoma with High Levels of CA125.

Int J Womens Health

March 2024

Department of Gynecology, Rizhao People's Hospital, Rizhao, Shandong Province, 276800, People's Republic of China.

Article Synopsis
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Article Synopsis
  • A 45-year-old woman was diagnosed with pseudo-Meigs' syndrome, which involved a benign ovarian tumor, fluid in the abdomen (ascites), and a significant pleural effusion affecting her breathing.
  • Laboratory tests indicated eosinophilia, meaning there were increased eosinophils (a type of white blood cell) in both her blood and pleural fluid.
  • Following surgery to remove the ovarian tumor (identified as a mature cystic teratoma), her pleural effusion improved, making her case of eosinophilic pleural effusion particularly rare in this syndrome.
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  • * Findings showed no significant differences in primary tumor size and density between the two groups, but the SUVmax and SUVmean values were significantly lower in the MS group.
  • * High Ca125 levels were positively correlated with serous fluid accumulation, and distinguishing MS from ovarian cancer can aid in accurate diagnoses prior to surgeries, as MS can involve benign tumors, ascites, and pleural effusions.
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