Assessing Heterogeneity Effects on Points A, B, and Organs at Risk Doses in High-dose-Rate Brachytherapy for Cervical Cancer - A Comparison of Ir and Co Sources Using Monte Carlo N-Particle 5.

Purpose: The present article deals with investigating the effects of tissue heterogeneity consideration on the dose distribution of Ir and Co sources in high-dose-rate brachytherapy (HDR-BT).

Materials And Methods: A Monte Carlo N-Particle 5 (MCNP5) code was developed for the simulation of the dose distribution in homogeneous and heterogeneous phantoms for cervical cancer patients. The phantoms represented water-equivalent and human body-equivalent tissues.