10 results match your criteria: "Medicine Faculty of Sfax University[Affiliation]"
Toxicol Mech Methods
June 2024
Laboratory of Induced and Development Diseases, Medicine Faculty of Sfax University, Sfax, Tunisia.
The current study aimed to assess the antioxidant and antiproliferative effects of extract: computational and study in rats. Three groups of animals: Group (i) constitute the control group; Group (ii) HeLa group received an intrafemoral inoculation of HeLa cells and Group (iii) constitue the combination between HeLa + . The plant was administered by gavage.
View Article and Find Full Text PDFBiofactors
November 2021
Laboratory of Histophysiology of Induced and Developmental Diseases, Medicine Faculty of Sfax University, Sfax, Tunisia.
Teucrium polium has been used in traditional medicine as antifungal, antipyretic, antispasmodic, and antibacterial. It is consumed by many jordanians for the treatment of many diseases. The effects of this plant have been investigated in kidney, liver, and brain.
View Article and Find Full Text PDFFront Physiol
February 2021
Animal Ecophysiology Laboratory, Sciences Faculty of Sfax, University of Sfax, Sfax, Tunisia.
This study is aimed to elucidate the possible antioxidant and protective effects of essential oil (ACEO) against the deleterious effects of chlorpyrifos (CPF) in rats. The study revealed increases in aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP) activities and the serum contents of creatinine, urea, uric acid, cholesterol, triglycerides, low density lipoproteins (LDL), and glucose in rats treated with CPF as compared to controls. Meanwhile, hepatic and renal activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver and kidney decreased and the content of malondialdehyde (MDA) increased.
View Article and Find Full Text PDFBiomed Pharmacother
July 2018
Laboratory of Histo-Embryology and Cytogenetics, Medicine Faculty of Sfax University, 3029, Sfax, Tunisia; Laboratory of Histology - Cytology, Medicine Faculty of Tunis, University of Tunis El Manar, 1007, La Rabta-Tunis, Tunisia. Electronic address:
This study was assessed to examine whether Zingiber officinale (ZO) can prevent spine disorder and trabecular microarchitecture disruption in osteoporotic murin model. Three groups of male rats were selected: Controls (CTRL), combined model of osteoporosis (CMO), in which rats were orchidectomized and treated with cortisol, and CMO treated with ZO (CMO + ZO). One month after the surgical procedures, the rats were sacrificed.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
June 2018
Laboratory of Histo-Embryology and Cytogenetics, Medicine Faculty of Sfax University, 3029, Sfax, Tunisia.
Our study was designed to evaluate impacts of exposure to pollutants, released by the Gabès-Ghannouche factory complex of phosphate treatment, on biochemical biomarkers and histopathological indices in kidney tissues of Hybrid sparrow (Passer domesticus × Passer hispaniolensis) in Gabès city. Our results show evidence of a pronounced impairment in kidney function which is confirmed by remarkable blood chemical alterations in sparrows living in Ghannouche, the most polluted site. Moreover, superoxide dismutase and catalase activities were found to be decreased in birds sampled from the contaminated site when compared to less polluted areas.
View Article and Find Full Text PDFArch Physiol Biochem
February 2018
a Laboratory of Histology , Medicine Faculty of Sfax University, Sfax , Tunisia.
This study aimed to investigate the protective effects of Teucrium polium (TP) on carbon tetrachloride (CCl) induced spleen, erythrocyte's oxidative stress, and genotoxicity in rats. TP was found to contain large amounts of polyphenols (150 mg GAE/G of dry plant) and flavonoids (60 mg QE/g of quercetin dry plant). The CCl (0.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
July 2017
Laboratory of Histo-Embryology and Cytogenetics, Medicine Faculty of Sfax University, 3029, Sfax, Tunisia.
Environmental pollution is a great concern worldwide. Our aim was to investigate the histopathological injuries and oxidative stress induced by exposure to contaminants in liver tissues of hybrid sparrows (Passer domesticus × Passer hispaniolensis) living in Gabès city, which is one of the most polluted hot spot in Tunisia. Our results show evidence of a pronounced impairment in liver function which is confirmed by histopathological changes as well as remarkable blood chemical alterations in sparrows living near the Gabès-Ghannouche factory complex of phosphate treatment.
View Article and Find Full Text PDFBiomed Pharmacother
July 2017
Laboratory of Histology, Medicine Faculty of Sfax University, 3029 Sfax, Tunisia.
Herbal drugs play a crucial function to protect organisms from the toxic effect of some compounds. The present study was designed to evaluate the protective effects of Teucrium Polium (TP) aqueous extract and vitamin C (Vit C) against carbon tetrachloride (CCl) which induced toxicity in rats. Male albino Wistar rats were divided into six groups: group I was used as controls, group II received CCl in olive oil (0.
View Article and Find Full Text PDFMed Biol Eng Comput
January 2017
Laboratory of Sciences Material and Environment, Faculty of Sciences of Sfax, B.P. 1171, 3000, Sfax, Tunisia.
This study investigated the effect of bioglass (melting)-polyvinyl alcohol (BG (M)-PVA) and bioglass (melting)-polyvinyl alcohol-20 %ciprofloxacin (BG(M)-PVA-20Cip) in improving antioxidant activity and regenerating bone capacity. These composites were implanted in femoral condyles of ovariectomized Wistar rats and compared to that of controls groups. After the different period of implantation (15, 30, 60 and 90 days), the treatment of ovariectomized rats with BG(M)-PVA-20Cip showed a significantly higher malondialdehyde concentration when compared to that of BG(M)-PVA group.
View Article and Find Full Text PDFEcotoxicol Environ Saf
July 2016
Laboratory of Histo-Embryology and Cytogenetic, Medicine Faculty of Sfax University, 3029 Sfax, Tunisia; Laboratory of Histology-Cytology, Medicine Faculty of Tunis El-Manar University, 1007 La Rabta-Tunis, Tunisia. Electronic address:
Air pollution is a threat for human health and wildlife. The aim of this study is to assess the pathophysiological changes and the oxidative-antioxidative status in testicular tissues of 40 Hybrid sparrows collected from four areas in Gabès city, one of the most polluted areas in Tunisia. The testis histopathological analysis revealed alterations in birds from Ghannouche, the polluted area.
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