11 results match your criteria: "Medical and Dentistry School[Affiliation]"

Iron deficiency and all-cause mortality after myocardial infarction.

Eur J Intern Med

August 2024

First Medical School, Charles University, Prague, Czech Republic; Department of Preventive Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. Electronic address:

Background: Data on the clinical significance of iron deficiency (ID) in patients with myocardial infarction (MI) are conflicting. This may be related to the use of various ID criteria. We aimed to compare the association of different ID criteria with all-cause mortality after MI.

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Article Synopsis
  • A study aimed to create a new score, called the PragueMi score, to predict mortality risk in patients after a myocardial infarction (heart attack) by using heart failure (HF) symptoms along with clinical factors.
  • The study analyzed data from 1,135 patients and found that key variables like age, history of heart failure, and symptoms experienced a month after discharge were crucial for the score.
  • The PragueMi score demonstrated better accuracy in predicting mortality risks at 6 months and 1 year compared to the existing GRACE score.
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Background: Heart failure is a common complication after myocardial infarction (MI) and is associated with increased mortality. Whether remote heart failure symptoms assessment after MI can improve risk stratification is unknown. The authors evaluated the association of the 23-item Kansas City Cardiomyopathy Questionnaire (KCCQ) with all-cause mortality after MI.

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  • The study investigates the impact of the rs7767652 minor allele T on mortality risk in patients who have experienced a myocardial infarction (MI) and its association with hypocretin/orexin signaling.
  • Data were collected from a registry of patients hospitalized for MI, revealing that those with the TT allele had a higher prevalence of complications like ventricular fibrillation and lower improvements in heart function post-MI.
  • Results indicate that reduced hypocretin/orexin signaling linked to the TT variant increases the risk of death after MI, partly due to greater arrhythmic risks and impaired heart recovery.
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Background: Left ventricular ejection fraction (EF) is an independent predictor of adverse outcomes after myocardial infarction (MI). However, current data on trajectories and determinants of EF are scarce. The present study aimed to describe the epidemiology of EF after MI.

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The aim is to evaluate the effects of photobiomodulation therapy (PBMT) on the guided bone regeneration process (GBR) in defects in the calvaria of rats filled with biphasic calcium phosphate associated with fibrin biopolymer. Thirty male Wistar rats were randomly separated: BMG ( 10), defects filled with biomaterial and covered by membrane; BFMG ( 10), biomaterial and fibrin biopolymer covered by membrane; and BFMLG ( 10), biomaterial and fibrin biopolymer covered by membrane and biostimulated with PBMT. The animals were euthanized at 14 and 42 days postoperatively.

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Fibrin biopolymers, previously referred as "fibrin glue" or "fibrin sealants", are natural biomaterials with diverse applications on health. They have hemostatic, adhesive, sealant, scaffold and drug delivery properties and have become widely used in medical and dental procedures. Historically, these biomaterials are produced from human fibrinogen and human or animal thrombin, and the possibility of transmission of infectious diseases by human blood is not ruled out.

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Fibrin sealants derived from human blood can be used in tissue engineering to assist in the repair of bone defects. The objective of this study was to evaluate the support system formed by a xenograft fibrin sealant associated with photobiomodulation therapy of critical defects in rat calvaria. Thirty-six rats were divided into four groups: BC ( = 8), defect filled with blood clot; FSB ( = 10), filled with fibrin sealant and xenograft; BC ( = 8), blood clot and photobiomodulation; FSB ( = 10), fibrin sealant, xenograft, and photobiomodulation.

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Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke.

Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial.

Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.

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Objectives: To examine the presence and morphologic characteristics of bifid mandibular canals (BMCs) and retromolar foramens (RFs) using cone beam CT (CBCT) and to determine their visualization on panoramic radiographs (PANs).

Methods: A sample of 225 CBCT examinations was analysed for the presence of BMCs, as well as length, height, diameter and angle. The diameter of the RF was also determined.

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Oncoplastic in a pre-paradigm era: a Brazilian perspective in an American problem.

Plast Reconstr Surg

June 2010

Breast Unit, Hospital Nossa Senhora das Graças, Department of Bioethics and Scientific Methodology, Positivo University Medical and Dentistry School, Curitiba, Brazil.

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