3 results match your criteria: "Medical University of x0141;x00F3;dx017A;[Affiliation]"
Application of the TaqMan ARMS-PCR Approach for Genotyping Drug-Induced Hearing Loss Using Dried Blood Samples.
Curr Issues Mol Biol
May 2024
Key Laboratory of Clinical Laboratory Diagnostics, Ministry of Education of China, School of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China.
Article Synopsis
- - The study identifies a specific mitochondrial DNA mutation, 1555A>G, linked to drug-induced hearing loss and outlines a new PCR detection method using allele-specific primers for accurate identification of this mutation.
- - This detection method achieves high sensitivity and specificity, being able to detect as few as 50 copies of DNA and down to 0.1 ng/μL in dried blood spots, and shows a mutation abundance detection limit of 0.78% in normal DNA samples.
- - The approach was validated with clinical samples from 113 newborns, demonstrating 100% agreement with the traditional Sanger sequencing, suggesting it could be a reliable option for clinical testing of deafness-related genes.
A Highly Sensitive Electrochemical Sensor for Capsaicinoids and Its Application in the Identification of Illegal Cooking Oil.
Biosensors (Basel)
September 2023
Key Laboratory of Clinical Laboratory Diagnostics, Ministry of Education of China, School of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China.
Capsaicinoids, mostly from chili peppers, are widely used in daily life. Capsaicinoids are considered to be markers for the identification of illegal cooking oil (ICO), which is a serious threat to public health. The identification of capsaicinoids can help reveal food-related fraud, thereby safeguarding consumers' health.
View Article and Find Full Text PDFPlasma Desphospho-Uncarboxylated Matrix Gla Protein as a Marker of Kidney Damage and Cardiovascular Risk in Advanced Stage of Chronic Kidney Disease.
Kidney Blood Press Res
March 2017
Department of Nephrology, Hypertension and Kidney Transplantation, Medical University of x0141;x00F3;dx017A;, Poland.
Background/aims: Desphospho-uncarboxylated matrix Gla protein (dp-ucMGP) is formed as a result of vitamin K insufficiency. The aim of this study was to investigate the association between plasma dp-ucMGP, kidney function and cardiovascular risk factors before and after 9-months substitution of vitamin K2 in non-dialysis patients with chronic kidney disease (CKD) stage 4 and 5.
Methods: 38 CKD patients were supplemented for 270±12 days with 90 µg vitamin K2 and 10 µg cholecalciferol or 10 µg cholecalciferol alone.