148 results match your criteria: "Medical University of the Americas[Affiliation]"

The posterior condylar canal: An anatomical study on dry human skulls.

Morphologie

November 2024

Comenius University Bratislava, Sasinkova 2, Bratislava 811 08, Slovak Republic. Electronic address:

Background: The human skull contains various foramina, including the posterior condylar canal (PCC), which allows the passage of emissary veins. The PCC connects the jugular foramen to the condylar fossa and facilitates venous drainage between the jugular bulb and suboccipital venous plexus. Due to its variable size and location, the PCC can be mistaken for pathological structures, posing challenges during neurosurgical procedures.

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  • This systematic review examines various studies on genetic markers linked to the risk of developing gastric cancer, focusing on specific genetic polymorphisms.
  • Significant markers identified include MUC1, PSCA, TNF-α, DNMTs, MMP-7, and IL-8, with their impact varying across different ethnic groups.
  • The review calls for more research into how these genetic factors influence cancer development and emphasizes the potential for personalized treatment strategies in gastric cancer management.
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Current and Emerging Immunotherapies for Systemic AL Amyloidosis.

Discov Med

September 2024

Department of Hematology-Oncology, Myeloma and Amyloidosis Program, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, USA.

Article Synopsis
  • Systemic light-chain (AL) amyloidosis is a rare condition caused by misfolded immunoglobulin light chains that accumulate in organs, leading to dysfunction and failure, especially when the heart is involved.* -
  • Treatment primarily focuses on eliminating the abnormal plasma cell growth, with the current first-line therapy being a combination of four drugs known as DaraCyborD; some patients may require stem cell transplants if this approach is insufficient.* -
  • Recent advancements include the use of monoclonal antibodies, like CAEL 101 and Birtamimab, aimed at breaking down amyloid deposits in affected organs, currently being tested in phase 3 trials for patients with significant cardiac involvement.*
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Ovarian teratomas are germ cell tumors composed of multiple cell types. Ovarian teratomas may express antigens found in the nervous system or neuroendocrine proteins. These neural antigens and neuroendocrine proteins may lead to an autoimmune response with associated encephalitis.

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Nihilistic delusions are unique psychopathological experiences characterized by the belief of being deceased, decayed, or obliterated. This case report sheds light on a patient grappling with nihilistic delusions, highlighting the strategies for treating and managing this psychiatric condition. The pathophysiology of Cotard's syndrome remains elusive, with proposed mechanisms being largely speculative.

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Premenstrual dysphoric disorder (PMDD) is a severe variant of premenstrual syndrome (PMS), categorized as a mood disorder due to marked symptoms of depression and anxiety, compounded with severe physical symptoms. Female sexual dysfunction (FSD) can manifest as low libido, difficulty achieving sexual pleasure, and dyspareunia, causing functional and psychological distress. PMDD and FSD are globally prevalent conditions with postulated biological, psychological, and social associations between them.

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Right Atrial Thrombus Masquerading as Myxoma.

Eur J Case Rep Intern Med

June 2024

Section of Cardiology, Department of Medicine, Tulane University Heart & Vascular Institute, New Orleans, USA.

Introduction: In-situ right atrial (RA) thrombus is a rare occurrence typically associated with heightened inflammatory or hypercoagulable states. Here, we present a case of in-situ RA thrombus mimicking atrial myxoma in a patient with sepsis and bacteraemia.

Case Description: A 41-year-old man presented with septic arthritis and bacteraemia caused by methicillin-resistant (MRSA).

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Diffuse alveolar hemorrhage (DAH), a rare complication of coexisting antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE), poses significant diagnostic and therapeutic challenges, especially with recurrent episodes. We present a 27-year-old male with catastrophic APS and SLE who experienced acute respiratory failure and hemoptysis due to DAH. Despite aggressive therapy with immunosuppressants, plasma exchange, and anticoagulation, he had recurrent DAH episodes requiring repeated admissions.

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Introduction: Oesophageal discontinuity remains a challenge for thoracic and foregut surgeons globally. Whether arising emergently after catastrophic oesophageal or gastric disruption or arising in the elective setting in the case of staged reconstruction for esophagectomy or long gap atresia in the paediatric population, comprehensive review of this patient population remains unexplored within the surgical literature.The goal of this scoping review is to map the landscape of literature exploring the creation and takedown of cervical oesophagostomy with the intent to answer four questions (1) What are the primary indications for oesophageal discontinuity procedures? (2) What are the disease-specific and healthcare utilisation outcomes for oesophageal discontinuity procedures? (3) What is the primary indication for reversal procedures? (4) What are the disease-specific and healthcare utilisation outcomes for reversal procedures?

Methods: This review will follow the Arksey and O'Malley (2005) framework for scoping reviews.

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Introduction:  Older adults are at increased risk of psychotic symptoms and even more at risk of medication nonadherence due to various factors specific to their age including memory impairment. This study aimed to examine the availability of long-acting injectable antipsychotics (LAIs) in US mental health (MH) facilities that serve older adults.

Methods: This study includes 1,216 MH facilities, using the 2022 National Substance Use and Mental Health Services Survey (N-SUMHSS) data from the Substance Abuse and Mental Health Services Administration (SAMHSA).

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has been recognized as the second most prevalent pathogen associated with diarrhea that contains blood, contributing to 12.9% of reported cases, and it is additionally responsible for approximately 200,000 deaths each year. Currently, there is no licensed vaccine.

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The planar cell polarity (PCP) system is essential for positioning cells in 3D networks to establish the proper morphogenesis, structure, and function of organs during embryonic development. The PCP system uses inter- and intracellular feedback interactions between components of the core PCP, characterized by coordinated planar polarization and asymmetric distribution of cell populations inside the cells. PCP signaling connects the anterior-posterior to left-right embryonic plane polarity through the polarization of cilia in the Kupffer's vesicle/node in vertebrates.

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Impact of Socioeconomic Status on Heart Failure.

J Community Hosp Intern Med Perspect

November 2023

Medical University of the Americas, P.O. Box 701, Charlestown, Nevis, West Indies, USA.

Heart failure has emerged as a substantial health burden in the United States in the last few decades. This study examined the hypothesis that socioeconomic factors such as education level, social position, employment status, and poverty have a strong confounding influence on the risk for heart failure. To access relevant data, 12 published studies were retrieved from MEDLINE, Google Scholar, and Web of Science.

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We report an exceptionally rare presentation of midgut volvulus secondary to malrotation in a nonagenarian female. According to our extensive literature review, this 90-year-old female is the oldest reported case of midgut volvulus. This patient presented with acute recurrent emesis.

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syndrome is a rare genetic disorder predisposing young patients to multiple types of cancer. A 17-year-old woman with a history of mixed Sertoli-Leydig cell tumor and juvenile granulosa cell tumor of the left ovary at age 14 presented with a pelvic mass. She underwent fertility preservation cytoreductive surgery and the pathology showed high-grade sarcoma with rhabdomyosarcomatous differentiation.

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BACKGROUND Cystocerebral syndrome is delirium occurring in the elderly that results from urinary retention and acute bladder distension. Urinary retention can cause cerebral issues, such as altered mental status, without having an infection present. The pathophysiology is possibly due to increased catecholamine secretion while attempting to micturate.

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Heart failure with reduced ejection fraction (HFrEF) is a clinical syndrome whose management has significantly evolved based on the pathophysiology and disease process. It is widely prevalent, has a relatively high mortality rate, and is comparatively more common in men than women. In HFrEF, the series of maladaptive processes that occur lead to an inability of the muscle of the left ventricle to pump blood efficiently and effectively, causing cardiac dysfunction.

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Radiology has been a pioneer in the healthcare industry's digital transformation, incorporating digital imaging systems like picture archiving and communication system (PACS) and teleradiology over the past thirty years. This shift has reshaped radiology services, positioning the field at a crucial junction for potential evolution into an integrated diagnostic service through artificial intelligence and machine learning. These technologies offer advanced tools for radiology's transformation.

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Hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome is a rare genetic disorder caused by a germline mutation in the fumarate hydratase (FH) gene. It is clinically characterized by cutaneous leiomyomas, uterine leiomyomas and renal cell cancer. A 31-year-old woman presented with severe abdominopelvic pain associated with severe menorrhagia which required a visit to the emergency department.

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