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A systematic review and meta-analysis on absolute eosinophil counts and the risk of asthma in preschool children with wheezing: An EAACI Task Force Report.
Pediatr Allergy Immunol
February 2024
Department of Paediatric Pneumonology and Allergy, Medical University of Warsaw Children's Hospital, Warsaw, Poland.
Article Synopsis
- - Preschool children with wheezing disorders face significant diagnostic and treatment challenges and have high healthcare costs associated with their care.
- - A review by the EAACI aimed to assess the relationship between elevated peripheral eosinophil blood count (EBC) and the likelihood of developing asthma later in life, revealing that higher EBC levels are linked to an increased asthma risk.
- - The analysis included 10 studies with 1225 preschool participants which suggested a cutoff of >300 EBC cells/μL correlates with higher asthma risk, but the consistency of defining specific cutoff points needs more research.