2 results match your criteria: "Medical University of South Carolina Department of Otolaryngology - Head and Neck Surgery.[Affiliation]"
Auditory nerve (AN) function has been hypothesized to deteriorate with age and noise exposure. Here, we perform a systematic review of published studies and find that the evidence for age-related deficits in AN function is largely consistent across the literature, but there are inconsistent findings among studies of noise exposure history. Further, evidence from animal studies suggests that the greatest deficits in AN response amplitudes are found in noise-exposed aged mice, but a test of the interaction between effects of age and noise exposure on AN function has not been conducted in humans.
View Article and Find Full Text PDFPrognostic Impact of High-Risk Pathologic Features in HPV-Related Oropharyngeal Squamous Cell Carcinoma and Tobacco Use.
Otolaryngol Head Neck Surg
May 2019
1 Medical University of South Carolina Department of Otolaryngology-Head and Neck Surgery, Charleston, South Carolina, USA.
Article Synopsis
- The study examined the effects of pathological features and tobacco use on the survival of patients with HPV-related oropharyngeal squamous cell carcinoma (OPSCC).
- HPV-positive heavy smokers had lower survival rates compared to nonsmokers, particularly in the presence of extranodal extension (ENE).
- Findings suggest that HPV-positive patients who are also heavy smokers may require more aggressive treatment strategies based on the new staging guidelines.