Impact of lateral ankle sprains on physical function, range of motion, isometric strength and balance in professional soccer players.

Objective: Lateral ankle sprains (LASs) are prevalent in soccer and can affect long-term performance, injury recurrence and risk for chronic ankle instability. This case-control study examined functional impairments associated with LAS in professional soccer players aged 17-21.

Methods: 40 players were divided into 2 groups: 21 with a history of LAS and 19 healthy matched controls.

Renewable energy transition in Europe in the context of renewable energy transition processes in the world. A review.

Both the global and European energy sectors have been undergoing a deep transition for several years, associated with a reduction in the overall share of conventional coal-based energy in favor of new technologies, especially energy from renewable sources (RES). This transition is moving from centralized production towards distributed technologies and from providing only energy to end users towards combining innovative products and services with it. Electricity consumers are becoming prosumers connected to the grid and generating an increasing amount of energy.

Clinical outcomes from robotic transabdominal preperitoneal inguinal hernia repair in patients under and over 70 years old: a single institution retrospective cohort study with a comprehensive systematic review on behalf of TROGSS - The Robotic Global Surgical Society.

Aim: This study aimed to assess and compare outcomes of robotic inguinal hernia repair (RIHR) in patients under and over 70 years old, performed by a fellowship-trained robotic surgeon at a single institution.

Methods: A retrospective analysis of patients undergoing robotic primary transabdominal preperitoneal inguinal hernia repair between 2020 and 2022 was conducted. Patients were categorized into two age groups: those under 70 years and 70 years and older.

Diffuse large B-cell lymphoma mimicking the cervical epidural hematoma in a patient who underwent spinal manipulation therapy: a case report and literature review.

The diffuse large B-cell lymphoma (DLBCL) mimicking an epidural hematoma in the cervical spine is an extremely unique case. We present a case of a 42-year-old man, who presented to the emergency department with symptoms of tetraparesis after a session of spinal manipulation therapy. magnetic resonance imaging visualized a lesion located at C3-C7 causing spinal cord compression with surrounding soft tissue edema suggesting epidural hematoma.

Impact of Clinical Factors on Accuracy of Ovarian Cancer Detection via Platelet RNA Profiling.

Ovarian cancer (OC) presents a diagnostic challenge, often resulting in poor patient outcomes. Platelet RNA sequencing, which reflects the host's response to disease, shows promise for earlier OC detection. This study examines the impact of sex, age, platelet count and the training on cancer types other than OC on classification accuracy achieved in the previous platelet-alone training dataset.

Reasons for Day-of-Surgery Cancellation of Elective Surgical Procedures During the COVID-19 Pandemic Compared to Pre- and Post-COVID-19 Periods.

Introduction: With the emergence of the global pandemic caused by SARS-CoV-2, health service providers were put to the test. The utilization of operating theatres is one of the prime indicators of the logistic and organizational efficacy of a hospital. We performed an analysis evaluating the impact of the COVID-19 pandemic on the fluidity of providing surgical care to a patient with severe comorbidities and the organizational efficacy of the operating theater in a university hospital in northern Poland.

Paroxysmal extreme pain disorder associated with a mutation in SCN9A gene - Case report and own experiences.

Introduction: Pain is an unpleasant sensory and emotional experience, influenced by various factors. Paroxysmal extreme pain disorder (PEPD) is a rare genetic condition characterized by sudden bouts of pain accompanied by autonomic symptoms.

Material Methods And Aim: This manuscript presents the case of a 9-year-old boy with paroxysmal extreme pain syndrome and provides a review of the literature.

Opinion of Polish doctors on the use of futile therapy.

The discontinuation of futile therapy is increasingly discussed in Polish clinical practice. Given the need to ensure patient well-being, it is essential to consider whether all clinical options resulting from medical progress should be used for every patient and on what grounds decisions to limit therapy should be based. The aim of our study was to determine the opinions of Polish medical doctors on this topic.

Treatment of HCV infection in patients with steatotic liver disease.

Aim Of The Study: The aim of the study was to characterize the population with hepatitis C virus (HCV) infection and steatotic liver disease (SLD) in comparison to the non-SLD HCV-infected patients and to evaluate the effectiveness of treatment with direct-acting antivirals (DAA).

Material And Methods: The analysis included 62 patients diagnosed with SLD and 14,284 non-SLD patients from the EpiTer-2 database for the period 2015-2022.

Results: Unlike the non-SLD population, the SLD group was dominated by men (49.

Effectiveness of glecaprevir/pibrentasvir in HIV/HCV-coinfected patients treated with bictegravir/emtricitabine/tenofovir alafenamide.

Aim Of The Study: To assess the real-life efficacy and safety of glecaprevir/pibrentasvir (GLE/PIB) in HIV/HCV- positive patients treated with bictegravir/emtricitabine/tenofovir alafenamide (B/FTC/TAF).

Material And Methods: Patients were evaluated in terms of their baseline biochemical characteristics, which included platelet count, serum creatinine and bilirubin levels, alanine transaminase (ALT) activity, international normalized ratio (INR) and Model for End-Stage Liver Disease (MELD) score.The efficacy endpoint was the achievement of a sustained virologic response at posttreatment week 12 (SVR12), defined as undetectable HCV RNA 12 weeks after the scheduled end of therapy.

PD-1 interactome in osteosarcoma: identification of a novel PD-1/AXL interaction conserved between humans and dogs.

The PD-1/PDL-1 immune checkpoint inhibitors revolutionized cancer treatment, yet osteosarcoma remains a therapeutic challenge. In some types of cancer, PD-1 receptor is not solely expressed by immune cells but also by cancer cells, acting either as a tumor suppressor or promoter. While well-characterized in immune cells, little is known about the role and interactome of the PD-1 pathway in cancer.

Metastatic breast cancer patients' preferences for exercise programs: a latent class analysis using data from a survey in five European countries.

Purpose: We aimed to identify metastatic breast cancer (MBC) patients' preferences for exercise programs and identify patients' characteristics associated with these preferences, to facilitate implementation of exercise programs for MBC patients.

Methods: We used data from a multinational cross-sectional survey conducted among MBC patients. Patients reported their preferred exercise frequency, intensity, type, session duration, and supervision mode.

Investigation of bioprintable modified agar-based hydrogels with antimicrobial properties.

Due to the numerous dangers arising from excessive use of antibiotics in treatments, researchers have been searching for natural alternatives to conventional antibiotics. Despite the popularity of plant extracts, essential oils, and their derivatives in herbal medicine, their applications in novel therapies are rather limited. This paper tries to open a new possibility for infection treatments by assessing the suitability of antimicrobial hydrogels as bioinks.

The bacterial burden of worn face masks-observational research and literature review.

Introduction: Facemasks were widely mandated during the recent SARS-CoV-2 pandemic. Especially the use by the general population is associated with a higher risk of improper handling of the mask and contamination and potential adverse microbiological consequences.

Methods: We investigated and quantified bacterial accumulation in facemasks used by the general population, using 16S rRNA (Sanger Sequencing), culture and biochemical analysis along with Rose Bengal staining.

Comorbidity in incident rheumatoid arthritis-a nationwide case-control study with bidirectional follow-up.

Objectives: To investigate the association between risk of different co-morbidities and diagnosis of rheumatoid arthritis (RA) using a temporal approach.

Methods: Retrospective, case-control study. Data were extracted from all healthcare claims for Poland between 2011-2021.

Does the Coronary Artery Bypass Grafting Impact the Survival of Men and Women Equally Compared to General Population? Results from KROK Registry and Polish Central Statistical Office.

The aim of this study was to evaluate the impact of coronary bypass surgery (CABG) on long-term mortality, comparing survival rates to those of the general population in Poland. The study was based on the Polish National Register of Cardiothoracic Surgical Procedures (KROK). Between January 2009 and December 2019, 133,973 patients underwent CABG.

Depression and Anxiety in 336 Elective Orthopedic Patients.

: Depression and anxiety are the two most common mental health disorders that can affect the well-being of the entire body. Multiple studies confirm that they can threaten the musculoskeletal system and the effects of orthopedic treatment as well. In turn, orthopedic disorders may worsen the symptoms of depression and anxiety.

Immediate Effect of Compression Contrast Therapy on Quadriceps Femoris Muscles' Regeneration in MMA Fighters.

This study aimed to evaluate the immediate effect of Game Ready (GR) heat-cold compression contrast therapy (HCCT) on changes in the biomechanical parameters of the quadriceps femoris muscles and tissue perfusion. Fifteen male MMA fighters were subjected to HCCT on the dominant leg's thigh and control sham therapy on the other. The experimental intervention used a pressure cuff with the following parameters: time-20 min; pressure-25-75 mmHg; and temp.

Adverse Reactions to Dry Needling Therapy: Insights from Polish Physiotherapy Practice.

: The current study aimed to characterize the adverse reactions associated with dry needling (DN) treatments reported by Polish physiotherapists, with a secondary objective of investigating whether the level of DN experience influences the occurrence of these adverse effects. : A total of 102 Polish physiotherapists, all with regular DN practice, participated in an ad hoc online survey. The participants were categorized by their level of experience in DN treatment: 44 with 0-2 years, 43 with 3-6 years, and 15 with more than 7 years of experience.

Factors Associated with Preoperative Anxiety in Patients Undergoing Ambulatory Hand Surgery: A Cross-Sectional Observational Study.

Studies examining preoperative anxiety in patients awaiting hand surgery are scarce. Preoperative anxiety is a common reaction and can have a negative impact on treatment outcomes. The aim of this study was to assess the level of anxiety in patients undergoing hand surgery as a one-day procedure and to investigate the associations between patients' preoperative anxiety and selected sociodemographic, psychological, and clinical variables.

Intricate Structure-Function Relationships: The Case of the HtrA Family Proteins from Gram-Negative Bacteria.

Proteolytic enzymes play key roles in living organisms. Because of their potentially destructive action of degrading other proteins, their activity must be very tightly controlled. The evolutionarily conserved proteins of the HtrA family are an excellent example illustrating strategies for regulating enzymatic activity, enabling protease activation in response to an appropriate signal, and protecting against uncontrolled proteolysis.