2 results match your criteria: "Medical Research Institute Surugadai Bldg[Affiliation]"

Slower immune system aging in women versus men in the Japanese population.

Immun Ageing

May 2013

Institute for Health and Life Sciences, Tokyo Medical & Dental University Open Laboratory, Medical Research Institute Surugadai Bldg, 2-3-10, Surugadai, Kanda, Chiyoda-ku, Tokyo 101-0062, Japan.

Background: Gender-related differences in humans are commonly observed in behaviour, physical activity, disease, and lifespan. However, the notion that age-related changes in the immune system differ between men and women remains controversial. To elucidate the relationship between immunological changes and lifespan, peripheral blood mononuclear cells from healthy Japanese subjects (age range: 20-90 years; N = 356) were analysed by using three-colour flow cytometry.

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Immunosenescence and cancer.

Crit Rev Oncog

June 2014

Tubingen Aging and Tumour Immunology Group (TATI), Section for Transplantation Immunology, Medizinische, Center for Medical Research, University of Tuebingen, Tuebingen, Germany.

The immune system, interacting intimately with the cancer cells in a tumor, may combat or favor cancer development and progression, or both. One of the most important risk factors for solid cancers is age. With increasing age, numerous alterations at multiple levels including molecular, cellular, organ, and systemic are occurring.

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