The effect of alendronate sodium on trabecular bone structure in an osteoporotic rat model.

Objectives: TObjectives: This study aims to investigate the effect of alendronate sodium on trabecular bone structure in an osteoporotic rat model.

Materials And Methods: Between May 2006 and July 2006, 60 female Wistar Albino rats aged three months were randomly allocated to three groups: sham operated receiving no treatment (Shm); ovariectomized-alendronate receiving 1 mg/kg/day alendronate sodium (Ovx-A), and ovariectomized-vehicle receiving 1 mL/kg/day physiological saline (Ovx-PS). Both Ovx groups received treatment through gastric gavage for 56 days.

Cusum analysis for learning curve of videothoracoscopic lobectomy.

Background: Video assisted thoracoscopic (VATS) lobectomy has a demanding learning curve due to its technical complexity and risk of uncontrollable bleeding. We investigated the case number required for gaining technical proficiency by applying cumulative sum analysis on initial VATS lobectomy operations of a single surgeon.

Methods: CALGB definition was used for the definition of VATS lobectomy.

Which Predicts Quadriceps Muscle Strength in Knee Osteoarthritis: Biological Markers or Clinical Variables?

Objectives: This study aims to evaluate the relationship between biological markers and quadriceps muscle strength, the correlation of clinical variables with quadriceps muscle strength, and the results according to the radiological severity in patients with knee osteoarthritis.

Patients And Methods: A total of 152 patients (22 males, 130 females; mean age 57.3±7.

A Rare Cause of Shoulder Pain: Monostotic Fibrous Dysplasia.

Fibrous dysplasia is a rare bone disease which has a wide spectrum of symptoms depending on the involvement area such as pain, deformity, fracture, dyspnea or visual loss. One of the rare involvement areas is the bones around the shoulder. Fibrous dysplasia presents in two forms named monostotic or polyostotic.

[Transcanal endoscopic tympanoplasty in the treatment of chronic otitis media].

Objectives: This study aims to report early postoperative complications and hearing results in patients with chronic otitis media undergoing endoscopic transcanal tympanoplasty.

Patients And Methods: Twenty-four patients (6 males, 18 females; mean age 25.9 years; range 9 to 46 years) who were operated with endoscopic transcanal tympanoplasty in the Department of Otorhinolaryngology, Faculty of Medicine, Çukurova University between December 2012 and January 2014 were included.

Screening tools for bacteraemia in a selected population of febrile children.

Introduction: This is a prospective, observational study. The aims of the study were to determine the rate of bacteraemia in febrile children in Turkey, and to evaluate the usefulness of white blood cell (WBC) count and manual differential counts of peripheral blood smears and a RISK score in predicting bacteraemia among these children.

Materials And Methods: A total of 377 febrile children aged 3 to 36 months were included in the study.

Interleukin-10 and -12 in human milk at 3 stages of lactation: a longitudinal study.

This study was undertaken to analyze postpartum changes in concentrations of interleukin (IL)-10 and IL-12 through the 3 stages of lactation. A total of 87 human milk samples were collected from 29 healthy mothers during the colostrum (0-3 days), early milk (14-17 days), and mature milk (44-47 days) phases. Enzyme-linked immunosorbent assay tests were performed on the milk samples.

Intramuscular Dipyrone versus Oral Ibuprofen or Nimesulide for Reduction of Fever in the Outpatient Setting.

Objective: To compare the effectiveness and rate of temperature reduction of three antipyretic medications in febrile children.

Design: A single-dose, randomised, prospective, modified double-blind, parallel clinical trial.

Setting: The paediatric emergency department of a university hospital that has 13 000 annual visits.

Chromosomal fragile site expression in Turkish psychiatric patients.

Chromosomal aberrations associated with psychiatric disorders may suggest regions in which to focus a search for genes predisposing to psychosis by a linkage strategy. Identification of these may be especially important given the unknown pathophysiology and the probable genetic heterogeneity of psychiatric disorders. In this study, the frequencies of folate sensitive fragile sites (FS) were compared among psychiatric disorders (e.

Erythrocyte pyruvate kinase activity during chemotherapy in children with leukemia and lymphoma.

Objectives: To determine both erythrocyte pyruvate kinase activity (ePKA) at the time of diagnosis of patients with acute leukemia or lymphoma and the differences in the ePKA profiles during the malignant disease and its chemotherapy.

Methods: A prospective, longitudinal clinical study was performed involving 57 patients, 10 were the ones with relapse of acute lymphoblastic leukemia, 32 were the ones with acute lymphoblastic leukemia (ALL) and 15 were the ones with lymphoma. None of the subjects in this study group received treatment or blood transfusion before the study, except the ones diagnosed with relapse of ALL.

Salbutamol intoxication: is salbutamol a drug-inducing fever? A case report and treatment strategy.

A four-year-old female with salbutamol intoxication was referred to our paediatric emergency medicine unit, due to agitation, tremulousness, sinus tachycardia, mild hypokalaemia and hyperglycaemia. On admission the child was agitated and had a noticeable tremor, an axillary temperature of 38 degrees C and a pulse rate of 185 beats/min. She had no identifiable focus of infection on physical examination to explain her fever.

Portal venous variations. Prevalence with contrast-enhanced helical CT.

Purpose: To review the distribution of intrahepatic portal venous branching in order to determine the prevalence of variations.

Material And Methods: We made a retrospective review of 655 contrast-enhanced helical CT (CECT) images of patients referred to our department for upper abdominal CT examination during an 8-month period. Of the 655 patients, 70 were eliminated from the study because of improper opacification of the portal venous system.

An infant with severe leucocyte adhesion deficiency.

A case of severe leucocyte adhesion deficiency occurred in a 6 1/2-month-old boy whose parents were first-degree cousins. Evidence of the disease first became apparent with the late separation of the umbilical cord on the 20th day and with the later development of omphalitis. The most specific finding was the very low levels of CD18 and CD11, 0.

Clinical features of Bardet-Biedl syndrome.

Six patients with Bardet-Biedl syndrome who have been followed in our clinics for the last 5 years are reported in this study. Of the five classic features of this syndrome; obesity and mental retardation were present in all cases, retinal disturbances were present in five, polydactyly in three and hypogenitalism was observed in all four male patients. Renal involvement, often suggested as a cardinal feature of this syndrome, was described in two patients.

HumFES/FPS and HumF13B: Turkish and German population data.

The allele distribution of two STRs has been investigated in two populations, i.e. Turks (n = 203/200) and Germans (n = 414/402).

Frequency profiles of 3 STRs in a Turkish population.

Population genetic studies were carried out on Caucasians from southern Turkey (n = 204 individuals) using the short tandem repeat (STR) systems HumTHO1, HumVWA and HumACTBP2. After electrophoresis in polyacrylamide gels, 6 alleles could be identified for HumTHOI, 7 alleles for VWA and 26 alleles for ACTBP2. No significant deviations from Hardy-Weinberg equilibrium could be observed.

Haemolytic crises due to glucose-6-phosphate dehydrogenase deficiency in the mid-southern region of Turkey.

Clinical and laboratory evaluation of 60 boys with hemizygous, 12 girls with homozygous, and 11 girls with heterozygous erythrocyte glucose-6-phosphate dehydrogenase deficiency was made during haemolytic crisis. The main clinical symptoms were paleness, dark urine and oliguria. Only one patient needed peritoneal dialysis.