[Analysis of subpopulation in Guangdong Han population].

To investigate the subpopulation structure within the Han Population in Guandong area, a total of 471 DNA samples from five populations in Guandong Province, including Guangzhou, Foshan, Dongguan, Jiangmen and Zhongshan-Zhuhai region, were genotyped at 15 STR(short tandem repeats) markers. Hardy-Weinberg tests were performed, allele frequencies were compared, and the genetic coancestry coefficient(FST) was estimated. The results did not show significant departure from Hardy-Weinberg equilibrium in the total population.

Neuroradiological findings of intracranial schwannomas not arising from the stems of cranial nerves.

Four cases of intracranial schwannomas not arising from the stems of cranial nerves are reported. All cases were confirmed by surgery and pathological examination. The related histogenesis and the CT and MRI findings are discussed, and the literature is reviewed.

The influence of central corneal thickness and corneal curvature and axial length on the measurement of intraocular pressure.

Purpose: To examine the influence of central corneal thickness (CCT), corneal curvature (CC), and axial length (AL) on intraocular pressure (IOP).

Methods: Eighty-one clinically normal eyes were included in our study. The IOP, CCT, CC, AL were measured using a Goldmann applanation tonometer, optical pachymeter, keratometer and A-scan ultrasound biometer respectively in all subjects.

Anti-proliferation effect of oridonin on HL-60 cells and its mechanism.

Objective: To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism.

Methods: HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred.

[Effect of ERK on 17beta-estradiol-induced inhibition of VSMC proliferation in rats after vascular injury].

The aim of the present study was to investigate the effect of ERK on 17beta-estradiol (E(2)) inhibition of vascular smooth muscle cell (VSMC) proliferation in rats after vascular injury. Common carotid artery balloon-injury (Inj) model was established in ovariectomized rats (OVX). Female SD rats were randomly divided into 4 groups: OVX, E(2)+OVX, OVX+Inj, and E(2)+OVX+Inj groups.