1 results match your criteria: "Medical College of Pennsylvania and Veterans Affairs Medical Center[Affiliation]"
CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption.
J Cell Biol
September 1999
Center for Osteoporosis and Skeletal Aging, Department of Medicine, Medical College of Pennsylvania and Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA.
The multifunctional ADP-ribosyl cyclase, CD38, catalyzes the cyclization of NAD(+) to cyclic ADP-ribose (cADPr). The latter gates Ca(2+) release through microsomal membrane-resident ryanodine receptors (RyRs). We first cloned and sequenced full-length CD38 cDNA from a rabbit osteoclast cDNA library.
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