1 results match your criteria: "Medical College of Nanchang University Jiangxi Institute of Medical Research[Affiliation]"
[Effects of IL-13 and alcohol on collagen expression of human lung fibrolasts].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
April 2011
Medical College of Nanchang University Jiangxi Institute of Medical Research, Key Laboratory of Medical Biotechnology, Nanchang 330006, China.
Aim: To investigate the effect of alcohol and/or IL-13 on the expression of collagen type I alpha 1 chain gene (COL1A1, COL3A1) mRNA and collagen production of human lung fibroblast(HFL-1).
Methods: HFL-1 was cultured and real time RT-PCR was used to determine the expression of IL-13 receptor (IL-13Rα1, IL-13Rα2, IL-4Rα) mRNA, COL1A1 mRNA and COL3A1 mRNA. ELISA was used to determine the production of collagen type I.