1 results match your criteria: "Medical College of Georgia at Augusta University (N.L.W.). huidy@ucmail.uc.edu.[Affiliation]"
Deficiency of LRP1 in Mature Adipocytes Promotes Diet-Induced Inflammation and Atherosclerosis-Brief Report.
Arterioscler Thromb Vasc Biol
June 2017
From the Department of Pathology, University of Cincinnati College of Medicine, OH (E.S.K., J.E.B., D.G.K., D.Y.H.); and the Division of Cardiology, Department of Medicine, Medical College of Georgia at Augusta University (N.L.W.).
Objective: Mice with adipocyte-specific inactivation of low-density lipoprotein receptor-related protein-1 (LRP1) are resistant to diet-induced obesity and hyperglycemia because of compensatory thermogenic response by muscle. However, the physiological function of LRP1 in mature adipocytes and its role in cardiovascular disease modulation are unknown. This study compared perivascular adipose tissues (PVAT) from wild-type () and adipocyte-specific LRP1 knockout () mice in modulation of atherosclerosis progression.
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