2 results match your criteria: "Medical Centre of West Kazakhstan Marat Ospanov Medical University[Affiliation]"
Colorectal cancer and microbiota: systematic review.
Prz Gastroenterol
March 2024
Department of General Surgery, Medical Centre of West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Introduction: The gut microbiome maintains the mucus membrane barrier's integrity, and it is modulated by the host's immune system.
Aim: To detect the effect of microbiota modulation using probiotics, prebiotics, symbiotics, and natural changes on colorectal cancers (CRCs).
Methods: A PubMed search was conducted to retrieve the original and articles published in English language from 2010 until 2021 containing the following keywords: 1) CRCs, 2) CRCs treatment (i.
Diagnostic and prognostic significance of keloid-like collagen remodeling patterns in the extracellular matrix of colorectal cancer.
Pathol Oncol Res
June 2024
Department of Pathomorphology, Medical Centre of West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Article Synopsis
- The study investigates the significance of keloid-like collagen (KC) in the stroma of colorectal cancer, specifically looking at its impact on patient outcomes for TNM stage II/III cases.
- Researchers examined 175 tumors, categorizing them into two groups based on KC presence and finding that higher KC levels (type B) were associated with worse prognosis compared to lower levels (type A).
- The results indicate that KC is an independent predictor of 5-year recurrence-free survival, suggesting that assessing KC could help in evaluating patient risks following surgery.