604 results match your criteria: "Medical Center School of Medicine[Affiliation]"

Background: To evaluate the ocular biometry agreement and prediction of postoperative refractive outcomes obtained using two swept-source optical coherence tomography (SS-OCT) biometers: Anterion (Heidelberg Engineering, Heidelberg, Germany) and Argos (Alcon, Fort Worth, TX, USA).

Methods: Ambispective analysis was conducted on 105 eyes at the Samsung Medical Center, Seoul, Republic of Korea, between June 2021 and March 2022. Biometric values were assessed using both devices before cataract surgery.

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Article Synopsis
  • * This study explores changes in personality perceptions, emotional expression, relationships, and anticipated life success in children after undergoing the Le Fort III surgery combined with distraction osteogenesis.
  • * Ultimately, the research aims to measure the importance of such surgical procedures on social perceptions, helping to inform patients and their families during the preoperative education process.
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Background: Mild behavioral impairment (MBI) has been associated with global brain atrophy, but the regional neural correlates of MBI symptoms are less clear, particularly among community-dwelling older individuals without dementia.

Objective: Our objective was to examine the associations of MBI domains with gray matter (GM) volumes in a large population-based sample of older adults without dementia.

Methods: We performed a cross-sectional study of 1445 community-dwelling older adults in the Atherosclerosis Risk in Communities Study who underwent detailed neurocognitive assessment and brain magnetic resonance imaging in 2011-2013.

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Objectives: Our study aims to explore the clinical characteristics of Omicron infection in pediatric liver transplant recipients (PLTRs), after the national COVID-19 outbreak. Additionally, we will investigate changes in vaccine coverage and parental attitudes towards vaccinating their children after this current outbreak.

Methods: We conducted a web-based questionnaire survey to gather information on Omicron infection, vaccination status, and guardian attitude among PLTRs.

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Study Design: Retrospective review.

Objective: Auricular hematomas are generally associated with sports-related injuries, with studies predominantly in white populations and high neighborhood socioeconomic status (NSES) compared to our county. A previous population-based study of trauma patients in our county, Shelby County, Tennessee, shows that those who live in high vs low NSES experienced socioeconomic variation in injury.

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Considerations regarding safety with pulsed field ablation for atrial fibrillation.

Heart Rhythm O2

September 2024

Division of Heart Rhythm, Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, Minnesota.

The introduction of pulsed field ablation (PFA) in electrophysiology marks a significant advancement, promising efficacy comparable to thermal ablation methods while potentially providing safety advantages. Despite a generally favorable safety profile in human trials and postmarket registries, cautious evaluation of PFA's safety is essential. This review provides a comprehensive overview of key safety considerations as we discuss a myriad of considerations ranging from thermal effects, gaseous microbubble formation, muscle contractions, and proarrhythmia to procedural techniques.

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Visual Outcomes and Patient Satisfaction of Enhanced Monofocal Intraocular Lens in Phacovitrectomy for Idiopathic Epiretinal Membrane.

Bioengineering (Basel)

September 2024

Department of Ophthalmology, Samsung Medical Center School of Medicine, Sungkyunkwan University, Seoul 06351, Republic of Korea.

Background: To evaluate the clinical outcomes and patient satisfaction after implantation of an enhanced monofocal intraocular lens (TECNIS Eyhance ICB00) in patients with idiopathic epiretinal membrane (ERM) who underwent cataract surgery with pars plana vitrectomy (PPV).

Methods: This is a single-center, retrospective, comparative study. In total, 61 eyes of 61 patients with idiopathic ERM and cataracts were included.

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Background: The demand for organ transplants, both globally and in South Korea, substantially exceeds the supply, a situation that might have been aggravated by the enactment of the Life-Sustaining Treatment Decision Act (LSTDA) in February 2018. This legislation may influence emergency medical procedures and the availability of organs from brain-dead donors. This study aimed to assess LSTDA's impact, introduced in February 2018, on organ donation status in out-of-hospital cardiac arrest (OHCA) patients in a metropolitan city and identified related factors.

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Objective: Mandibular distraction osteogenesis (MDO) is rapidly becoming a standard of care for management of patients with severe Pierre Robin sequence. The tongue is brought forward to alleviate airway obstruction. This study will look at an institutional, multisurgeon experience with MDO over 10 years.

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Objective: Excess adiposity represents a risk factor for chronic kidney disease (CKD) and progression to end-stage kidney disease. Anti-Obesity Medications (AOMs) are vastly underutilized in patients with advanced CKD because of concerns related to safety and efficacy. This study was conducted to evaluate the real-world approach to weight management and the efficacy and safety of AOMs in people with advanced CKD.

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Total hip arthroplasty is an effective procedure to improve pain, range of motion, and function for a variety of conditions, including osteoarthritis and posttraumatic arthritis. Up to 28% of patients had persistent pain at the surgical site 12-18 mos after total hip arthroplasty, even in the absence of surgical complications. Currently, there are no widely accepted nonpharmacological treatments for persistent postoperative pain for total hip arthroplasty.

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Background: Human endogenous retrovirus (HERV)-K is a type of retrovirus that is present in the human genome, and its expression is usually silenced in healthy tissues. The precise mechanism by which HERV-K env influences cancer stemness is not fully understood, but it has been suggested that HERV-K env may activate various signaling pathways that promote stemness traits in cancer cells.

Objective: To establish the connection between HERV-K env expression and cancer stemness in ovarian cancer cells, we carried out correlation analyses between HERV-K env and the cancer stem cell (CSC) marker known as the cluster of differentiation 133 (CD133) gene in SKOV3 ovarian cancer cells.

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Limitations of and Solutions to Using 6 mm Corneal Spherical Aberration and Q Value after Laser Refractive Surgery.

Bioengineering (Basel)

February 2024

Department of Ophthalmology, Samsung Medical Center School of Medicine, Sungkyunkwan University, Seoul 06351, Republic of Korea.

This study aimed to evaluate the spherical aberration (SA) in different corneal areas before and after femtosecond laser-assisted in situ keratomileusis (fLASIK) and transepithelial photorefractive keratectomy (tPRK), with the goal of identifying the limitations of and potential improvements in using SA within a 6 mm area. The study included 62 patients who underwent fLASIK and tPRK. Complete eye examinations including keratometry, corneal epithelial thickness, central corneal thickness, and topography were performed preoperatively and postoperatively.

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Big Data in Health Care: An Interprofessional Course.

Nurse Educ

June 2024

Author Affiliations: Assistant Professor (Dr Calcote), The University of Mississippi Medical Center School of Nursing, Jackson; Professor and Chair (Dr Mann), Department of Preventive Medicine, The University of Mississippi Medical Center School of Medicine, Jackson; Professor (Dr Adcock), Pharmacy Division, The University of Mississippi Medical Center School of Pharmacy, Jackson; Professor (Dr Duckworth), The University of Mississippi Medical Center Division of Internal Medicine, Jackson; and Medical Student M3 (Mr Donald), The University of Mississippi Medical Center School of Medicine, Jackson.

Background: The widespread adoption of the electronic health record (EHR) has resulted in vast repositories of EHR big data that are being used to identify patterns and correlations that translate into data-informed health care decision making.

Problem: Health care professionals need the skills necessary to navigate a digitized, data-rich health care environment as big data plays an increasingly integral role in health care.

Approach: Faculty incorporated the concept of big data in an asynchronous online course allowing an interprofessional mix of students to analyze EHR big data on over a million patients.

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Article Synopsis
  • Systemic immune activation, indicated by elevated levels of C-reactive protein (CRP) and interleukin-6 (IL-6), affects immune responses in patients with non-small cell lung cancer (NSCLC) undergoing treatment with immune checkpoint inhibitors (ICIs).
  • The study assessed the link between CRP levels, patient outcomes like overall survival (OS) and progression-free survival (PFS), and explored the immune mechanisms associated with these factors.
  • Results indicated that patients with high CRP at baseline (CRP-H) had significantly poorer outcomes, including shorter OS and PFS, and that CRP-H was an independent predictor of increased mortality risk and lower disease response rate
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Article Synopsis
  • * Conducted over 14 years across multiple U.S. sites, it analyzed data from 2,174 pregnant individuals who provided urine samples and completed depression screenings within a year after childbirth.
  • * Results showed that virtually all participants had detectable levels of several harmful chemicals, highlighting a potential area for reducing PPD risk through dietary and lifestyle changes.
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Background: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an effective and evidence-based treatment for idiopathic Parkinson's disease (iPD). A minority of patients does not sufficiently benefit from STN-DBS.

Objective: The predictive validity of the levodopa challenge for individual patients is analyzed.

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Women with PCOS who undergo IVF: a comprehensive review of therapeutic strategies for successful outcomes.

Reprod Biol Endocrinol

August 2023

Section of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, Yale University, New Haven, CT, USA.

Article Synopsis
  • Polycystic ovarian syndrome (PCOS) is a common condition that makes it hard for some women to get pregnant and can affect IVF treatments.
  • Doctors are still debating what the best methods are for helping women with PCOS during IVF, including preparing their bodies and managing egg growth.
  • To improve chances of success, it’s important for women with PCOS to consider their health measures like weight, vitamin levels, and use helpful supplements before starting IVF.
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Metabolic regulation of glucagon secretion.

J Endocrinol

September 2023

Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Denmark.

Since the discovery of glucagon 100 years ago, the hormone and the pancreatic islet alpha cells that produce it have remained enigmatic relative to insulin-producing beta cells. Canonically, alpha cells have been described in the context of glucagon's role in glucose metabolism in liver, with glucose as the primary nutrient signal regulating alpha cell function. However, current data reveal a more holistic model of metabolic signalling, involving glucagon-regulated metabolism of multiple nutrients by the liver and other tissues, including amino acids and lipids, providing reciprocal feedback to regulate glucagon secretion and even alpha cell mass.

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Article Synopsis
  • * Using functional magnetic resonance imaging (fMRI), researchers measured blood flow changes in key brain areas linked to reward and control before and after administering naltrexone.
  • * Results showed that naltrexone altered brain activation patterns, indicating its potential as a biomarker for drug response in ED treatment, with implications for future therapeutic development and personalized dosing.
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Perceived Value of Public Health and Health Policy Information Among Medical Students: A Cross-sectional Study.

PRiMER

May 2023

University of Kansas Medical Center School of Medicine, Kansas City, KS | University of Kansas Medical Center, Department of Family Medicine and Community Health, Kansas City, KS.

Unlabelled: : Health educators have had difficulty introducing health policy and public health training into an already intensive medical school curriculum. Although the COVID-19 pandemic may have changed perspectives on the importance of public health, it may not change educational approaches. Assessment of medical student opinions and perceptions of health policy and public health might influence the weight given to these topics in medical education.

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The Potential for Using ChatGPT to Improve Imaging Appropriateness.

J Am Coll Radiol

October 2023

Director of the Northwest Screening and Cancer Outcomes Research Enterprise, Department of Radiology, University of Washington School of Medicine, Seattle, Washington; and Deputy Editor of JACR. Electronic address: https://twitter.com/christophleemd.

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Objectives: Head and neck cancer is a common malignancy frequently treated with chemotherapy and radiotherapy. Studies have shown an increased risk of stroke with the receipt of radiotherapy, but data on stroke-related mortality are limited, particularly in the modern era. Evaluating stroke mortality related to radiotherapy is vital given the curative nature of head and neck cancer treatment and the need to understand the risk of severe stroke in this population.

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The Alliance of Leaders in Academic Affairs in Radiology (ALAAR) advocates for a Universal Curriculum Vitae for all medical institutions and to that end, we have developed a template that can be downloaded on the AUR website (ALAAR CV template) that includes all of the elements required by many academic institutions. Members of ALAAR represent multiple academic institutions and have spent many hours reviewing and providing input on radiologists' curricula vitae. The purpose of this review is to help academic radiologists accurately maintain and optimize their CVs with minimal effort and to clarify common questions that arise at many different institutions in the process of constructing a CV.

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