2,616 results match your criteria: "Mediastinum Germ Cell Tumors"
Medicine (Baltimore)
December 2024
Department of Urology, Gansu Provincial Hospital, Lanzhou, China.
Rationale: Pheochromocytomas typically arise in the adrenal medulla, whereas ectopic pheochromocytomas/paragangliomas commonly occur near the abdominal aorta, bladder, mediastinum, and head. Diaphragmatic pheochromocytomas are exceedingly rare, and there is limited surgical experience with their treatment.
Patient Concerns: In Case A, the subject is a 45-year-old male, while in Case B, the subject is a 59-year-old female.
Kyobu Geka
November 2024
Department of General Thoracic, Breast and Endocrinological Surgery, Kagawa University, Kagawa, Japan.
A 36-year-old woman referred to our hospital for treatment of a mediastinal tumor. Contrast computed tomography (CT) scan was revealed a 31×21×25 mm mass in the anterior mediastinum, with low contrast, clear border, and a tendency to increase. On magnetic resonance imaging( MRI) examination, the anterior mediastinal tumor showed homogeneous high signal intensity on T1-weighted images and a combination of high and low signal intensities on T2-weighted images.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Department of Pathology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1H 8L1, Canada.
Ann Thorac Surg
November 2024
Division of Thoracic Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA. Electronic address:
Cureus
September 2024
General Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.
J Cancer Res Ther
July 2024
Department of Pathology, Rajiv Gandhi Cancer Institute and Research Center, Delhi, India.
Int J Surg Case Rep
November 2024
Department of Cardiology, Alwatani Hospital, Hama University, Hama, Syria.
Int Cancer Conf J
October 2024
Department of Respiratory Medicine, University of Tsukuba Hospital, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8575 Japan.
Kyobu Geka
September 2024
Department of Thoracic Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
J Cardiothorac Surg
October 2024
Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Road, Jinan, Shandong Province, 250021, China.
Neuropathology
October 2024
Department of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Germ cell tumors (GCTs) are categorized as gonadal or extra-gonadal, based on the origin. Extra-gonadal GCTs predominantly manifest within the central nervous system (CNS), mediastinum, retroperitoneum, and sacrococcygeal region. These malignancies are most frequently diagnosed in the pediatric, adolescent, and young adult demographics.
View Article and Find Full Text PDFBMC Pediatr
September 2024
Shantou University Medical College, Shantou University, 22 Xinling Road, Jinping District, Shantou, 515041, China.
Objectives: Mediastinal cystic lymphatic malformation (MCLM) in children is prone to misdiagnosis as cystic teratoma. We compared the clinical and radiologic features between the two diseases and performed a cross-comparison with previous research on adult cases. This study aims to identify characteristic pediatric manifestations to improve diagnostic accuracy.
View Article and Find Full Text PDFCytopathology
January 2025
Rutgers Robert Wood Johnson, New Brunswick, New Jersey, USA.
Medullary thyroid carcinoma (MTC) is an uncommon neuroendocrine tumour that is usually asymptomatic at its onset and therefore may not present clinically until the patient has developed advanced or metastatic disease. Common metastatic sites include cervical lymph nodes, liver, bone and lung. This is the case of a patient who presented with an incidental posterior mediastinal mass.
View Article and Find Full Text PDFInt J Clin Oncol
November 2024
Department of Urology, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Objectives: Mediastinal germ cell tumors are rare and few large-scale studies on mediastinal germ cell tumors are reported. We aimed to investigate the clinical characteristics and survival outcomes of patients with mediastinum germ cell tumors in Japan.
Methods: A hospital-based cancer registry data in Japan was used to identify and enroll patients diagnosed with mediastinal germ cell tumors in 2012-2013.
J Investig Med High Impact Case Rep
September 2024
Palestine Medical Complex (PMC), Ramallah, Palestine.
J Cardiothorac Surg
September 2024
Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Mediastinum
June 2024
Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
This review article comprehensively examines the diagnostic approach to thymic epithelial tumors (TETs) and other mediastinal masses, focusing on imaging modalities and differential diagnosis. Beginning with a discussion on traditional and contemporary classification systems for mediastinal tumors, including the Japanese Association for Research on the Thymus (JART) and International Thymic Interest Group (ITMIG) classifications, it highlights the shift towards computed tomography (CT)-based categorizations. Emphasis is placed on the importance of distinguishing between solid and cystic lesions in the anterior mediastinum, with detailed insights into imaging characteristics and histological features of various TET subtypes such as thymomas, thymic carcinomas, and thymic neuroendocrine tumors (NETs).
View Article and Find Full Text PDFReprod Domest Anim
August 2024
Federal University of Cariri (UFCA), Crato, Ceará, Brazil.
Cureus
June 2024
Pulmonary and Critical Care Medicine, Staten Island University Hospital, Staten Island, USA.
We describe a rare and remarkable transformation of an immature mediastinal teratoma into high-grade angiosarcoma in a 21-year-old male. Mediastinal teratomas, particularly immature ones, are exceedingly rare, representing a small fraction of germ cell tumors (GCTs). Our case describes the clinical journey of the patient, who initially presented with acute chest pain and was subsequently diagnosed with an immature teratoma following imaging studies and elevated tumor markers.
View Article and Find Full Text PDFBMC Pediatr
July 2024
Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Background: Ganglioneuromatosis is a rare type of benign neurogenic tumor that usually affects the sites of the major sympathetic ganglia in the retroperitoneum and the posterior mediastinum. Affection of the gastrointestinal tract is rare, and involvement of the esophagus is exceptional. To the best of our knowledge, only 4 cases of esophageal ganglioneuromatosis in adults were reported in the literature.
View Article and Find Full Text PDFPathology
October 2024
Department of Pathology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Electronic address:
Case Rep Obstet Gynecol
May 2024
Department of Obstetrics and Gynecology Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Introduction: Primary extragonadal germ cell tumors (EGCTs) are a very rare clinical encounter most commonly reported in males. Among females, the placenta, pelvis, uterus, brain, and mediastinum are the most common extragonadal sites and predominantly display nondysgerminoma histology. In this report, we present a case of a primary cervical dysgerminoma in a young female patient.
View Article and Find Full Text PDFHistopathology
November 2024
Institute of Pathology, University Medical Center, Göttingen, Germany.
Mediastinum
February 2024
Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
Background And Objective: Giant anterior mediastinal tumors sometimes may cause circulatory collapse and respiratory failure, known as mediastinal mass syndrome (MMS). The prediction and prevention of MMS is challenging. The aim of this study is to summarize the evaluation methods for MMS and formulate treatment strategies for giant anterior mediastinal tumors.
View Article and Find Full Text PDFClin Case Rep
June 2024
Department of Cardiology, School of Medicine Shiraz University of Medical Sciences Shiraz Iran.
Key Clinical Message: The key takeaway from this clinical scenario is to choose the most appropriate and reasonable treatment plan when dealing with a patient who has atrial septal defect (ASD) and concurrent atrial and mediastinal masses. In such cases, a heart-oncology team should make the therapeutic decision.
Abstract: Right atrial masses are not pretty rare and might be a diagnostic challenge.