316 results match your criteria: "Medeniyet University Faculty of Medicine[Affiliation]"

This study was aimed to identify the most frequently observed pathogens in uncomplicated urinary tract infections from outpatient urinary isolates obtained across seven different geographical regions in Türkiye and to determine whether the antibiotic resistance rates of these pathogens differ significantly between these regions. The study included patients aged 18 to 65 years who were diagnosed with uncomplicated urinary tract infections and had positive urine cultures from March 2021 to August 2022, across 37 different centers in Türkiye. The participating centers were selected based on their use of the disk diffusion method, in line with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, to ensure standardization of urine culture data.

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Objective: This study aims to compare the results of cases with a history of assault presented to our emergency department over a period of three years with literature data and to share our experiences with colleagues.

Methods: Demographic characteristics, trauma findings, clinical conditions, surgical interventions, mortality, and outcomes of patients with a history of assault to the emergency department between 2020 and 2022 were retrospectively examined. The results were analyzed using the Number Cruncher Statistical System 2007 Statistical Software package program (Utah, USA).

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Objective: This study aimed to compare the effectiveness of different mesotherapy techniques applied at various dermal depths on pain, functional status, and quality of life in patients with non-specific neck pain.

Methods: A total of 43 patients who received mesotherapy for non-specific neck pain were retrospectively analyzed. Patients treated with the point-by-point technique (n=21) and the napaj technique (n=22) were recorded.

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Introduction: Intravenous immunoglobulin (IVIG) is an alternative for post-exposure prophylaxis if a vaccine is contraindicated and intramuscular immunoglobulin is unavailable. We retrospectively examined the effect of IVIG administration time on measles development in measles-contact infants younger than 6 months of age.

Methodology: Contact tracing of measles cases was performed by the Istanbul Public Health Directorate (IPHD) between August 24, 2012, and June 16, 2013.

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Objective: Coronavirus Disease 2019 (COVID-19) has affected every aspect of human life and all health care systems globally. The aim of this study was to investigate the effect of COVID-19 pandemic on the frequency, presentation and surgical outcomes of complicated appendicitis.

Methods: Patients who underwent appendectomy for acute appendicitis one year before and one year after the declaration of the pandemic were investigated.

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Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Res Pract Thromb Haemost

October 2024

Department of Internal Medicine, Division of Hematology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

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Article Synopsis
  • * It found that the RSV only group had lower pH and higher rates of bronchiolitis, while the RSV with viral agents group experienced longer hospital stays and more severe symptoms.
  • * Additionally, cases with bacterial co-infections were generally younger and had different clinical markers, highlighting that combined viral and bacterial infections can worsen RSV severity and impact treatment approaches like High Flow Nasal Cannula-Oxygen Therapy.
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Background: Decreased bladder compliance is an important risk factor for upper urinary tract in children with neurogenic bladder dysfunction (NBD). Urodynamics is the gold standard in determining bladder compliance.

Objective: To investigate the relationship between low bladder compliance and urinary fibrosis markers in NBD.

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Objective: The purpose of this study is to demonstrate the potential effects of thymoquinone, a well-known antioxidant agent, on random flap viability and thus to improve the clinical use of these flaps.

Methods: In this study, 24 Sprague Dawley female albino rats weighing between 200-250 grams were used. Three groups consisting of randomly selected 8 rats were formed, as study, sham and control groups.

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Objective: There is a known association between lower urinary tract dysfunction (LUTD) and constipation. The objective of this study was to investigate any correlation between voiding and bowel symptoms in children with LUTD.

Methods: Children presenting with LUTD to our pediatric urology unit were prospectively included.

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Objective: The aim was to evaluate the outcomes of conventional anorectal manometry (ARMM) testing and biofeedback therapy in adolescents with functional constipation.

Methods: A retrospective analysis of ARMM findings in patients aged 10-18 years with intractable constipation over a 4-year period was conducted.

Results: Of the 41 patients (mean age, 13.

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Common viral respiratory infections in children with cancer during the COVID-19 pandemic: a multicenter study from Türkiye.

Turk J Pediatr

October 2024

Department of Pediatric Hematology Oncology, Yıldırım Beyazıt University Faculty of Medicine, Ankara Bilkent City Hospital, Ankara, Türkiye.

Article Synopsis
  • During the COVID-19 pandemic lockdown, the study assessed respiratory viral infections in children with cancer, highlighting their clinical impact.
  • Of the 265 episodes evaluated, human rhinovirus/enterovirus was the most common pathogen identified, with significant complications noted, including a higher rate of lower respiratory tract infections.
  • The findings emphasize the necessity for quicker detection and treatment of respiratory viruses to prevent severe outcomes in this vulnerable population.
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Article Synopsis
  • The musculocutaneous nerve bypassed the coracobrachialis, sending a branch to the median nerve instead, with both the median nerve and brachial artery situated underneath the additional muscle head.
  • These anatomical differences may increase the risk of nerve and vascular issues during surgeries, highlighting the importance of careful pre-surgical assessment and awareness during procedures.
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Article Synopsis
  • - The study investigates how TET2 gene knockdown in acute myeloid leukemia (AML) cells affects their dependence on extracellular glutamine and their ability to survive in low-glutamine environments.
  • - TET2-knockdown HL-60 cells showed decreased growth in glutamine-deficient conditions, yet they remained more viable than control cells, suggesting a potential adaptive mechanism.
  • - Increased GLUL mRNA expression and P-AMPKα protein levels were observed in TET2-knockdown cells under low-glutamine conditions, indicating that these cells may have heightened reliance on glutamine for survival.
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Objective: Bronchopulmonary dysplasia (BPD) is among the most common complications of prematurity and is associated with high morbidity and mortality rates. Acute kidney injury (AKI) is also commonly observed in premature infants and significantly increases morbidity and mortality. Studies have shown that systemic changes in AKI may also trigger lung damage.

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The current classification fails to fully meet the needs of physicians and COPD patients in clinical practice. The future classification should aim to prevent the development of disease in high-risk groups, enable early diagnosis before irreversible damage occurs, identify subgroups, and provide pathophysiological insight to inspire drug development. It would be reasonable to thoroughly examine and assess the contributing factors such as an increase in the annual decline of (FEV1), bronchial hyperresponsiveness, variable obstruction, FEV1 % predicted, blood eosinophil count, preserved ratio impaired spirometry (PRISm), and the subgroups of group B as potential additions to the new classification.

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Hypertensive disorders of pregnancy are significant contributors to maternal and perinatal morbidity and mortality. The definition, classification, and management of these disorders have evolved over time. Notably, the disease classification enables caretakers to manage the disease as well as safeguard maternal and fetal health.

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Article Synopsis
  • In Turkey, a single-dose varicella vaccine was introduced in February 2013, aiming to reduce hospitalizations related to chickenpox among children under 18 years old.
  • A study analyzed hospitalization data from 2008 to 2018, comparing rates before and after the vaccine's introduction, finding a significant decrease in hospitalizations (3.79 to 2.87 per 100,000 children per year).
  • The most notable reduction was in children aged 1-5 years, with a 60.2% drop in hospitalizations post-vaccine, demonstrating the vaccine's effectiveness in preventing severe cases of varicella.
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Article Synopsis
  • * The relationship between muscle force and bone health is crucial as decreased muscle activity can lead to bone loss, a concern not yet fully studied in clinical settings.
  • * The review examines how the use of BTX can disrupt the balance between muscles and bones, potentially leading to conditions like osteopenia and increased bone resorption, especially in instances such as spinal cord injuries.
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Can the efficacy of a medical treatment be predicted based on the type of idiopathic premature ventricular contraction?

J Electrocardiol

September 2024

Cardiology Department, Istanbul Medeniyet University Faculty of Medicine, Goztepe Training and Research Hospital, Dr. Erkin street, 34722 Istanbul, Turkey.

Background: Premature ventricular contractions (PVCs) are common arrhythmias with diverse clinical implications. This retrospective study aimed to evaluate the efficacy of medical treatments using various clinical, imaging, and electrocardiographic parameters in patients with idiopathic PVCs.

Methods: A total of 1051 patients with idiopathic PVCs were retrospectively analyzed.

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Background And Objectives: Crush injury, the most important trauma complication encountered in earthquake victims, occurs as a result of prolonged compression of muscle mass. Crush syndrome, resulting from crush injury, and acute kidney injury (AKI) are the most common causes of in-hospital deaths after earthquakes. The aim of this study is to convey our experience after the devastating Turkey-Syria earthquake and to identify the risk factors of crush syndrome and crush-related AKI.

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Introduction: The aim was to evaluate the effect of preoperative anxiety on the sympathetic block that developed after spinal anesthesia and therefore the duration of motor and sensory blockade.

Materials And Methods: After the approval of the ethics committee, 90 patients between the ages of 18 and 55 years who were to be operated under spinal anesthesia were included in the study. Preoperative anxiety of the patients was evaluated with the Spielberger trait and State Anxiety Scale and Visual Analog Scale (VAS).

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Objective: The purpose of this study is to evaluate whether hepatosteatosis is associated with lung cancer in patients undergoing lung nodule biopsy.

Methods: 359 patients (248 males, 69.1%) who underwent lung biopsy between the years 2016 and 2022 were included in this retrospective study.

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