93 results match your criteria: "Mazda Hospital.[Affiliation]"

Purpose: To investigate whether the pivot-shift test reflects patient-reported outcomes 1 year after anterior cruciate ligament (ACL) reconstruction based on a multicentre prospective cohort study.

Methods: This study included patients who underwent primary ACL reconstruction using the hamstring tendons. The pivot-shift test grades were determined according to the International Knee Documentation Committee (IKDC) form as 0, 1+, 2+ or 3+.

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The purpose of this study was to investigate factors that influence clinical outcomes after anterior cruciate ligament (ACL) reconstruction in patients aged ≥40 years. We studied 264 patients aged ≥40 and 154 patients aged ≤20 years who underwent ACL reconstruction at several surgical centers. A logistic regression analysis was conducted to identify factors that influenced the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 1 year post-ACL reconstruction.

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Reply to letter to the editor by Li et al.

J Orthop Sci

September 2024

Department of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Japan.

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Article Synopsis
  • The study aimed to find a more efficient and acceptable method for bowel preparation before colonoscopy, comparing two different regimens using MoviPrep and a modified dietary approach.
  • Conducted at multiple hospitals, the trial involved 380 participants divided into three groups to test the effectiveness and adherence of different prep methods.
  • Results showed that using Mov with a Modified Brown Method led to significantly shorter bowel preparation times without affecting total intake volume, and Mov with laxatives resulted in less abdominal distension compared to other methods.
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Background: There are no studies examining changes in the physical function throughout the baseball season in Japanese professional players. We examined the range of motion (ROM) and muscle strength changes in professional baseball pitchers as the season progresses.

Materials And Methods: Five professional baseball pitchers were included.

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  • - The study aimed to systematically review how capsular repair during hip arthroscopy affects patient-reported outcomes and the need for total hip arthroplasty (THA) in individuals with femoroacetabular impingement syndrome.
  • - Researchers analyzed 5 studies involving 639 patients, comparing outcomes for those who underwent capsular repair versus those who did not, using the modified Harris Hip Score as a measurement tool.
  • - Results indicated that capsular repair showed a positive impact on patient-reported outcomes (standardized mean difference of 0.42) and was linked to a reduced need for conversion to THA, but did not significantly lower the revision surgery rates.
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Background: The aim of this study was to investigate the prognostic impact of postoperative infections in patients who underwent resection for biliary malignancy, including intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma, distal cholangiocarcinoma, gallbladder carcinoma, and carcinoma of the ampulla of Vater.

Methods: This study was conducted in an 11-center retrospective cohort study. Patients with biliary tract cancer who underwent curative resection between April 2013 and March 2015 at 11 institutions in Japan were enrolled.

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Aim: This study was performed to evaluate the oncological impact of surgical site infection (SSI) and pneumonia on long-term outcomes after esophagectomy.

Methods: The Japan Society for Surgical Infection conducted a multicenter retrospective cohort study involving 407 patients with curative stage I/II/III esophageal cancer at 11 centers from April 2013 to March 2015. We investigated the association of SSI and postoperative pneumonia with oncological outcomes in terms of relapse-free survival (RFS) and overall survival (OS).

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A single site study to investigate the current prevalence of anti-hepatitis C virus antibody among substance use disorder patients in Hiroshima-Insufficient testing and diagnosis.

Neuropsychopharmacol Rep

December 2023

Department of Collaborative Research Laboratory of Medical Innovation, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Aims: Hepatitis C virus (HCV) infection among drug users presents an important public health problem; however, little recognition and few approaches to address this issue in Japan. This study was conducted to investigate the current disease status by assessing anti-HCV antibody (Ab) seroprevalence among people who inject drugs (PWIDs) and people who use drugs (PWUDs) in Hiroshima, Japan.

Methods: This study was a psychiatric single-site chart review in patients with drug abuse problems in the Hiroshima region.

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Hippocampal volumetry to determine the resection side in patients with intractable non-lesional bilateral temporal lobe epilepsy.

Sci Rep

February 2023

Department of Neurosurgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Bilateral Temporal lobe epilepsy (BTLE) cases may result in poor surgical outcomes due to the difficulty in determining/localizing the epileptogenic zone. In this study, we investigated whether hippocampal volume (HV) would be useful for the determination of the best resection side in BTLE. Eighteen cases of BTLE determined by a scalp video electroencephalogram (SVEEG) underwent resection via intracranial electroencephalography (IVEEG).

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Background: Stress shielding and osteolysis around the humeral stem after reverse shoulder arthroplasty causes loosening and periprosthetic fractures and reduces bone stock during revision surgery. In Japanese patients, who have relatively small bodies, different characteristics may exist regarding the occurrence of these changes compared with the characteristics of Westerners, who have relatively larger frames. The purpose of this multicenter study was to investigate the incidence and clarify the predictors of stress shielding and osteolysis in Japanese individuals who underwent reverse shoulder arthroplasty.

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Article Synopsis
  • - The study aimed to assess how postoperative infections (PI), surgical site infections, and remote infections affect long-term outcomes in colorectal cancer patients after surgery.
  • - In a cohort of 1,817 patients, it was found that 16.5% experienced postoperative infections, leading to significantly worse cancer-specific survival rates compared to those without infections.
  • - The findings indicate that postoperative infections mainly hinder the effectiveness of adjuvant chemotherapy and emphasize the need for strategies to prevent infections post-surgery to improve overall patient outcomes.
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Association Between Patient Preference for Inhaler Medications and Asthma Outcomes.

J Asthma Allergy

October 2022

Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Purpose: Asthma guidelines recommend considering the patient preference to optimize medication choices. Patient preference for inhaler medication may affect asthma outcomes, but evidence regarding this is lacking. This study investigated the associations between patient preference for inhaler medications and asthma outcomes.

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Prognostic impact of postoperative infection in patients with pancreatic cancer: A multicenter cohort study.

Surgery

December 2022

Department of Surgery, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan; Clinical Research Support Committee, Japan Society for Surgical Infection, Tokyo, Japan.

Background: Postoperative infection after pancreatectomy in patients with pancreatic cancer often leads to poor prognosis. The aim of this study was to determine the prognostic effect of postoperative infection in patients with pancreatic cancer.

Methods: A multicenter cohort study was performed using a common database of patients with pancreatic cancer who underwent curative pancreatic resections between April 2013 and March 2015 at 15 high-volume centers in Japan.

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Evaluation of urinary catheters for effective manual bladder washout.

Sci Rep

August 2022

Department of Urology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.

Our purpose was to evaluate the efficiency of manual bladder washout (MBW) for bladder retention by blood clot formation using urinary catheters. Three types of 22 Fr urinary catheters, a rounded tip Foley catheter (FC) with the standard two eyes, an open-ended Nelaton catheter (NC) with a side hole, and an open-ended Foley catheter (OEFC) with a side hole closer to the tip than NC, were evaluated. An automatic irrigation device that could perform a predetermined procedure mimicking MBW under constant velocity was fabricated.

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Prevalence of fatty liver and advanced fibrosis by ultrasonography and FibroScan in a general population random sample.

Hepatol Res

November 2022

Department of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Aim: Fatty liver is the most common liver disease. This study examined fatty liver and advanced fibrosis prevalence in a random sample of the Japanese general population.

Methods: A total of 6000 people randomly selected from two cities in Hiroshima Prefecture were invited to participate in this cross-sectional study originally carried out for hepatitis virus screening.

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Prevalence of Helicobacter pylori infection in the general population evaluated by a resident-register-based epidemiological study.

J Gastroenterol

August 2022

Department of Epidemiology Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Article Synopsis
  • A study was conducted to evaluate the current prevalence of Helicobacter pylori infection in the general population of Japan using a large-scale random sampling method.
  • The results showed that 40.0% of participants tested positive for H. pylori, with a higher prevalence in rural areas compared to urban areas, particularly among older adults.
  • The findings highlight a decrease in infection rates among younger individuals and serve as foundational data to help develop strategies aimed at reducing gastric cancer mortality.
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Introduction: Blount disease is a growth disorder of the medial proximal tibial physis causing a multi-planar deformity of the lower limb. Several types of surgical approaches have been described for the correction of angular deformity including external fixation, opened-/closed- wedge high tibial osteotomy (HTO), and tibial condylar valgus osteotomy. However, they are associated with various disadvantages such as limb length discrepancy, risk of infections, and delayed union at the osteotomy site, especially in cases of severe varus deformity.

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Purpose: To assess the postoperative anatomical changes in the lower extremity after inverted V-shaped high tibial osteotomy (IVHTO) using 3-dimensional (3D) computed tomography (CT) bone models and compare those changes after closed-wedge high tibial osteotomy (CWHTO).

Methods: Preoperative and 3-week postoperative CT scanning of the lower extremity were obtained from patients who underwent IVHTO and CWHTO between October 2019 and March 2021. 3D CT bone models were reconstructed using ZedKnee software.

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Background: Prehospital stroke triage scales help with the decision to transport patients with suspected stroke to suitable hospitals.

Objective: To explore the effect of the region-wide use of the Japan Urgent Stroke Triage (JUST) score, which can predict several types of stroke: large vessel occlusion (LVO), intracranial hemorrhage (ICH), subarachnoid hemorrhage (SAH), and cerebral infarction other than LVO (CI).

Methods: We implemented the JUST score and conducted a retrospective and prospective multicenter cohort study at 13 centers in Hiroshima from April 1, 2018, to March 31, 2020.

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A larger side-to-side difference in anterior knee laxity increases the prevalence of medial and lateral meniscal injuries in patients with ACL injuries.

Knee Surg Sports Traumatol Arthrosc

May 2022

Department of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Purpose: The objective of this study was to investigate factors that influence the prevalence of medial and lateral meniscal injuries at the time of anterior cruciate ligament (ACL) reconstruction in patients with ACL injuries.

Methods: Patients with ACL injuries at 9 institutions were enrolled in this multicentre study. Age, sex, duration between injury and surgery, pivot shift test grade, anterior knee laxity determined using the Kneelax 3 arthrometer, and other variables were assessed by logistic regression analysis.

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Inappropriate antimicrobial therapy for surgical site infections (SSIs) can lead to poor outcomes and an increased risk of antibiotic resistance. A nationwide survey was conducted in Japan from 2018 to 2019 to investigate the antimicrobial susceptibility of pathogens isolated from SSIs. The data were compared with those obtained in 2010 and 2014-2015 surveillance studies.

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Objective Lusutrombopag is a thrombopoietin receptor agonist that improves thrombocytopenia in patients with chronic liver disease scheduled to undergo invasive procedures. However, information on the efficacy of repeated lusutrombopag treatment and factors associated with the treatment is scarce. We analyzed the efficacy of repeated lusutrombopag treatment and the factors associated with a response to lusutrombopag.

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The Japanese Dermatological Association prepared the clinical guidelines for the "Wound, pressure ulcer and burn guidelines", second edition, focusing on treatments. Among them, "Guidelines for wounds in general" is intended to provide the knowledge necessary to heal wounds, without focusing on particular disorders. It informs the basic principles of wound treatment, before explanations are provided in individual chapters of the guidelines.

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Article Synopsis
  • The study is the first of its kind in Japan, surveying antimicrobial susceptibility in 246 samples from patients with various odontogenic infections, revealing high positivity rates for bacterial growth across four infection groups.
  • Streptococcus spp. and anaerobic bacteria were the main isolates, with notable resistance in Prevotella spp. to certain antibiotics due to β-lactamase production, though no resistance was found against carbapenems or metronidazole.
  • Sensitivity testing indicated that while penicillins and cephems were generally effective, Prevotella spp. required combination therapy involving β-lactamase inhibitors for better treatment outcomes.
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