3 results match your criteria: "Max Rady College of Medicine University of Manitoba Winnipeg Canada.[Affiliation]"

Background And Aims: Hypertension is the leading preventable risk factor for cardiovascular disease, chronic kidney disease and cognitive impairment, and mortality and disability worldwide. Since prevention, early detection, and treatment of blood pressure improve public health, the aim of present study was to determine the best obesity indices and estimate the optimal cut-off point for each one to predict the risk of elevated/stage 1 and undiagnosed hypertension in the population of center of Iran based on American ACC/AHA 2020 guidelines.

Methods: This cross-sectional study was performed on 9715 people who enrolled in 2018 in Persian Adult Cohort in Shahedieh area of Yazd, Iran in 2018.

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Background And Aims: Pharmacists have been recognized as one of the most qualified healthcare professionals in the clinical implementation of pharmacogenomics, yet its widespread implementation in clinical pharmacy practice has remained limited. The review aims to systematically investigate knowledge, perceptions, and attitudes toward pharmacogenomics among pharmacists and pharmacy students to inform the future delivery of pharmacogenomics education programs.

Methods: PubMed, MEDLINE, Embase, Scopus, and the International Pharmaceutical Abstracts were searched up to May 17, 2022.

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Article Synopsis
  • Pyruvate carboxylase deficiency is an autosomal recessive genetic disorder with different subtypes, where type A is characterized by severe developmental delays and metabolic issues in infants.
  • A study reported neuroimaging findings in a 33-week gestation infant with a specific genetic mutation, showing significant brain abnormalities that indicate issues with brain development due to this deficiency.
  • These brain anomalies were present without metabolic decompensation, suggesting that pyruvate carboxylase is crucial for normal brain development and highlighting that type A and type B PC deficiencies might represent a spectrum of clinical symptoms rather than separate categories.
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