Monkeypox (Mpox): Diagnosis and Emerging Challenges.

Monkeypox (Mpox) has once again been designated a Public Health Emergency of International Concern (PHEIC) as of August, 2024. The severity of the disease is underscored by its significant mortality rate, and unfortunately, there are no targeted therapeutics currently available for this viral infection. Management relies on preventive measures and the use of existing smallpox vaccines due to their genetic similarity to the Mpox virus.

Spontaneous Intrathoracic Rupture of Abdominal Neuroblastoma in a 2-year-old Child: A Rare Case Report.

Neuroblastoma (NB) tumor rupture, typically intra-abdominal, is a rare and life-threatening condition with a poor prognosis, often associated with large aggressive tumors. Intrathoracic ruptures, rarely reported, may result from thoracic NB or malignant invasion. We present the first case of spontaneous intrathoracic rupture in a 2-year-old boy with abdominal NB.

Mycoplasma pneumoniae among children hospitalized in a tertiary hospital with community-acquired lower respiratory tract infections.

Purpose: In this prospective study incidence of Mycoplasma pneumoniae (M. pneumoniae) infection was investigated in children with community-aquired lower respiratory tract infections (LRTIs) using methods such as serology, nested PCR (polymerase chain reaction), and multiplex PCR analysis.

Methods: M.

Exploration of the transfluthrin effects on fertility and pregnancy outcomes: An in-vivo study in rat.

Transfluthrin (TFL) is a rapid-acting pyrethroid insecticide, commonly used worldwide, however its overuse and or misuse has been associated with adverse effects on human health. This study was designed to investigate the impact of TFL on fertility and pregnancy in Sprague-Dawley rats exposed orally and by inhalation. In this study, 48 adult Sprague-Dawley rats of 6-8 months age group were randomly selected with equal numbers of males and females.

Barriers and facilitators for the use of telehealth by healthcare providers in India-A systematic review.

It is widely assumed that telehealth tools like mHealth (mobile health), telemedicine, and tele-education can supplement the efficiency of Healthcare Providers (HCPs). We conducted a systematic review of evidence on the barriers and facilitators associated with the use of telehealth by HCPs in India. A systematic literature search following a pre-registered protocol (https://doi.

Unveiling geographic conjunctival ulcer: a rare clinical presentation of herpetic eye disease.

A male patient in his 50s presented with a history of sudden onset redness and pain in the right eye for 15 days. He was under prescription of topical antibiotics, steroids and lubricants by the primary treating ophthalmologist for 2 weeks with reported worsening of symptoms. He was noted to have a visual acuity of 20/32 and 20/20 in the right and left eye, respectively.

Safety assessment of the world's first novel cocktail of two monoclonal antibodies in WHO category-III animal-bite patients.

Background: Rabies, a zoonotic disease, poses a significant global public health challenge, and post-exposure prophylaxis (PEP) is crucial for prevention. Monoclonal antibodies (mAbs) have emerged as a promising alternative to rabies immunoglobulins due to their high efficacy and standardized manufacturing process.

Materials And Methods: A prospective, open-label post-marketing surveillance study was conducted with patients of WHO category-III suspected rabid animal bites.

Predictors of citations and altmetric scores in general surgery literature.

Objectives: This study aimed to determine various article characteristics influencing the citations and altmetric scores using papers published in a year in four high-ranking surgery journals.

Material And Methods: We included all papers (n= 819 articles) published between January 2015 to December 2015 in the Annals of Surgery, British Journal of Surgery, JAMA Surgery and Journal of American College of Surgeons. Article characteristics were manually extracted.

Effect of Maternal Iodine Excess during Pregnancy on Neonatal Thyroid Function and Neurodevelopmental Status at 12 Weeks.

Objective: This study aims to determine the effect of iodine excess in pregnant mothers on thyroid function, growth and neurodevelopment in the neonates when assessed at 12 weeks of age.

Methodology: This prospective study enrolled term neonates with birth weight >2500 gm of mothers having urine iodine concentration (UIC) ≥500 µg/L documented in the third trimester of the peripartum period. Neonatal TSH was collected by heel prick on dried blood spots within 24-72 hours of age and measured by time-resolved fluroimmunoassay.

Digital gangrene without sclerodactyly in the presence of anticentromere antibodies: A unique presentation of scleroderma.

Peripheral vascular disorders associated with anti-centromere antibody (ACA) present generally with sclerodactyly in connective tissue disorders (CTD). It is unusual for ACA-associated digital necrosis to develop without preexisting raynaud's phenomena or vascular risk factors. We report a novel case of a 60-year-old non-smoker, non-diabetic woman with ACA and isolated finger necrosis without any other features of CTD.

Predicting unicompartmental arthroplasty success: a three year Indian study.

Purpose: This study evaluated the three year clinical outcomes and predictors of success for unicompartmental knee arthroplasty (UKA) in an Indian population.

Methods: Twenty patients with medial compartment osteoarthritis (≥ Ahlbäck grade 2) underwent UKA. American Knee Society Score (AKSS), Oxford Knee Score (OKS), and Visual Analogue Scale Score (VAS) were assessed at baseline, two weeks, six weeks, three months, and three years.

Recurrent Dermatofibrosarcoma Protuberans Over the Face: A Challenging Clinical Problem.

Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin malignancy known for its high recurrence rate. It predominantly affects the trunk and extremities but can occasionally present on the face. A 47-year-old man presented with a rapidly progressive, painless swelling on the left side of his face for six months.

Psychological problems and burnout among healthcare workers: Impact of non-pharmacological lifestyle interventions.

Objective: To evaluate role of rajyoga meditation (RYM) versus stress management counselling (SMC) in addressing burnout syndrome and resultant improvement in electrocardiogram (ECG) so as to automate burnout prediction from raw ECG data with machine learning (ML).

Methods: Healthcare providers were assigned to two groups: RYM (n = 100) or SMC (n = 102). Subjects in RYM received rajyoga for 3 months including one week offline and thereafter, virtual mode.

Quitting tobacco through quitline services: impact in India.

Tobacco quitline services offer telephone-based counseling to assist tobacco users in quitting through behavioral modification. It is a sponsored scheme by the Ministry of Health and Family Welfare, Government of India. The present study has two objectives: primarily, to study the correlation between socio-demographic variables and tobacco abuse, and secondly, to study the impact of National Tobacco Quit-Line Services (NTQLS) in India.

Hindi Translation, Cultural Adaptation, and Validation of Modified Weight Bias Internalization Scale (WBIS-M): A Cross-Sectional Study from the Metabolic Surgery Clinic in North India.

Background: The lack of culturally-sensitive tool masks the epidemiology of weight-bias and internalized-stigma. This study aimed to translate, adapt, and validate the Modified Weight-Bias Internalization Scale (WBIS-M) into Hindi.

Methods: The translation and adaptation process followed the World Health Organization guidelines.

Sinonasal Organized Hematoma: A Preoperative & Intraoperative Diagnostic Evaluation of Two Cases.

Sinonasal Organized hematoma (SOH) is a rare, benign condition that can mimic the malignancy of sinonasal region. It typically involves the maxillary sinuswith extra sinus involvement being a rare presentation. .