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Histopathological safety evaluation of polyethylene glycol applied subcutaneously in mice.
J Int Med Res
September 2004
Department of Hard Tissue Research, Matsumoto Dental University Graduate School, Division of Hard Tissue Research, Matsumoto Dental University Institute for Oral Science, Shiojiri, Japan.
Polyethylene glycol is used as a non-aqueous solvent for a variety of medical agents. We believe it could also be used as a base component in root canal filling material and aimed to test the histological safety of subcutaneously injected polyethylene glycol. We injected polyethylene glycol subcutaneously into the dorsal area of 30 6-week-old anaesthetized male ddY mice.
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