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Integrating Contrast-enhanced US to O-RADS US for Classification of Adnexal Lesions with Solid Components: Time-intensity Curve Analysis versus Visual Assessment.

Radiol Imaging Cancer

November 2024

From the Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Guangzhou 510630, Guangdong, China (M.W., Y.W., M.S., L.H., X.Z.); Department of Ultrasound, Henan Provincial People's Hospital, Zhengzhou, China (R.W.); Department of Ultrasound, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (X.S.); Department of Ultrasound, Children's Hospital of Shanxi (Women Health Center of Shanxi), Taiyuan, China (R.Z.); Ultrasound Diagnosis Center, Shaanxi Provincial People's Hospital, Xi'an, China (L.M.); Department of Ultrasound, The Fifth People's Hospital of Chengdu, Chengdu, China (L.X.); Department of Ultrasound, Huizhou Central People's Hospital, Huizhou, China (H.W.); Department of Ultrasound Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China (T.L.); and Department of Ultrasound, The Third Hospital of BaoGang Group, Maternity Hospital of Bao Tou, Baotou, China (X.M.).

Article Synopsis
  • The study aimed to evaluate how effective time-intensity curve (TIC) analysis and subjective visual assessment of contrast-enhanced ultrasound (CEUS) are when combined with the Ovarian-Adnexal Reporting and Data System (O-RADS) for diagnosing adnexal lesions with solid components.
  • Conducted at multiple centers from September 2021 to December 2022, the study analyzed 180 lesions from 175 women, comparing diagnostic performances using receiver operating characteristic curves.
  • Results showed that integrating CEUS with O-RADS significantly improved diagnostic accuracy (AUC 0.86) compared to O-RADS alone (AUC 0.78), and both CEUS assessment methods (TIC and subjective assessment
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Objectives: To evaluate the additional advantages of integrating contrast-enhanced ultrasound (CEUS) into the Ovarian-Adnexal Reporting and Data System (O-RADS) ultrasound (US) for the characterization of adnexal lesions with solid components.

Materials And Methods: This prospective multicenter study recruited women suspected of having adnexal lesions with solid components between September 2021 and December 2022. All patients scheduled for surgery underwent preoperative CEUS and US examinations.

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