5 results match your criteria: "Maternal and Child Health-Care Hospital in Guiyang[Affiliation]"
Long-term Pegylated GH for Children With GH Deficiency: A Large, Prospective, Real-world Study.
J Clin Endocrinol Metab
July 2023
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Context: The evidence of long-term polyethylene glycol recombinant human GH (PEG-rhGH) in pediatric GH deficiency (GHD) is limited.
Objective: This study aimed to examine the effectiveness and safety of long-term PEG-rhGH in children with GHD in the real world, as well as to examine the effects of dose on patient outcomes.
Design: A prospective, observational, posttrial study (NCT03290235).
[Analysis of clinical phenotype and genotype of Chinese children with disorders of sex development].
Zhonghua Er Ke Za Zhi
May 2022
Department of Pediatrics, First People's Hospital of Yunnan Province, Kunming 650032, China.
To explore the heterogeneity and correlation of clinical phenotypes and genotypes in children with disorders of sex development (DSD). A retrospective study of 1 235 patients with clinically proposed DSD in 36 pediatric medical institutions across the country from January 2017 to May 2021. After capturing 277 DSD-related candidate genes, second-generation sequencing was performed to analyzed the heterogeneity and correlation combined with clinical phenotypes.
View Article and Find Full Text PDFCorrigendum: Reduced Effectiveness and Comparable Safety in Biweekly Weekly PEGylated Recombinant Human Growth Hormone for Children With Growth Hormone Deficiency: A Phase IV Non-Inferiority Threshold Targeted Trial.
Front Endocrinol (Lausanne)
December 2021
Department of Pediatric Endocrinology and Inherited Metabolic Diseases, Children's Hospital of Fudan University, Shanghai, China.
[This corrects the article DOI: 10.3389/fendo.2021.
View Article and Find Full Text PDFReduced Effectiveness and Comparable Safety in Biweekly Weekly PEGylated Recombinant Human Growth Hormone for Children With Growth Hormone Deficiency: A Phase IV Non-Inferiority Threshold Targeted Trial.
Front Endocrinol (Lausanne)
February 2022
Department of Pediatric Endocrinology and Inherited Metabolic Diseases, Children's Hospital of Fudan University, Shanghai, China.
Context: Long-acting recombinant human growth hormone (rhGH) has transformed growth hormone deficiency (GHD) treatment. However, the possibility and rationality for flexible time regimen are pending.
Objective: We studied the efficacy of biweekly weekly PEGylated rhGH (PEG-rhGH) therapy in GHD children.
Chromoendoscopy Plus Mucosal Resection Versus Conventional Electrocoagulation for Intestinal Polyps in Children: Two Case Series.
J Laparoendosc Adv Surg Tech A
November 2018
Department of Gastroenterology, Maternal and Child Health-Care Hospital in Guiyang, Guiyang, China .
Background: Conventional high-frequency electrocoagulation (HFEC) of intestinal polyps may be difficult in children and endoscopic mucosal resection (EMR) could be a less invasive option. Chromoendoscopy improves tissue localization during endoscopy, but its exact influence on the outcomes of children with intestinal lesions is still unknown.
Aims: To analyze a series of children treated with EMR or HFEC and assess the value of chromoendoscopy.