22 results match your criteria: "Maternal and Child Health Hospital of Gansu Province[Affiliation]"

Cow's milk protein allergy is the most common food allergy in infants and young children, and its prevalence has been increasing in recent years. The use of appropriate diagnostic methods is essential for the management of patients. Oral food challenges are not yet widely used in clinical practice, and new and more effective methods are still being sought, including component resolved diagnosis.

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Incidence and risk factors of female sexual dysfunction in urban and rural China: a 4-year prospective cohort study.

Front Med

December 2024

Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Common Mechanism Research for Major Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.

Article Synopsis
  • This study explored female sexual dysfunction (FSD) in urban and rural China, following 16,827 women aged 20 and above over a median period of 4.13 years from 2014 to 2018.
  • The overall 4-year incidence of FSD was 43.07%, with higher rates in rural women (45.68%) compared to urban women (41.03%).
  • Key risk factors identified included age (≥45 years), hypertension, previous pregnancies, post-menopausal status, and pelvic inflammatory disease, with variations in risk factors between urban and rural populations.
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A rare transcript homozygous variants in CLRN1(USH3A) causes Usher syndrome type 3 in a Chinese family.

Orphanet J Rare Dis

September 2024

Department of Otolaryngology-Head and Neck Surgery, Lanzhou University Second Hospital, No. 82 Cuiyingmen, Lanzhou, Gansu, 730030, PR China.

Article Synopsis
  • - Usher syndrome type 3 (USH3) is an inherited disorder linked to mutations in the CLRN1 gene, leading to hearing and vision impairments.
  • - A study analyzed a three-generation deaf-blind Chinese family to establish how specific genetic variants correlated with the disease symptoms, identifying significant differences in mutations across various gene transcripts.
  • - The unique mutation CLRN1:c.474T > A, discovered in this family, is confirmed as the cause of USH3 and highlights the necessity of considering different genetic transcripts in mutation analysis.
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The incidence of urinary incontinence in Chinese hypertensive women and the relationship between hypertension and urinary incontinence.

Eur J Obstet Gynecol Reprod Biol

October 2024

Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Common Mechanism Research for Major Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

Objectives: To determine the incidence of UI (urinary incontinence) and its subtypes in hypertensive women and examine the association between hypertension and new-onset UI.

Study Design: We conducted a cohort study on women aged ≥20 years in six regions of China. This cohort study was carried out from 2014 to 2016 at baseline, with follow-up completed in 2018.

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Objective: We aimed to evaluate the genotype-phenotype relationship in two Chinese family members with enlarged vestibular aqueduct (EVA).

Methods: We collected blood samples and clinical data from each pedigree family member. Genomic DNA was isolated from peripheral leukocytes using standard methods.

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Objective: In this study, serum markers of acute ischemic stroke (AICS) with carotid artery plaque were retrospectively evaluated to establish a basis for discovering serological indicators for early warning of acute ischemic stroke (AICS).

Methods: A total of 248 patients with AICS were enrolled in Lanzhou University Second Hospital from January 2019 to December 2020. The study population included 136 males and 112 females, 64 ± 11 years of age.

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Purpose: We estimated the remission and transition rate between urinary incontinence (UI) subtypes in women with UI and evaluated the impact of body mass index (BMI) on this process.

Materials And Methods: A Chinese population-based longitudinal study was conducted. Women aged ≥20 years were included using a multistage, stratified, cluster sampling method.

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Incidence and risk factors of female urinary incontinence: a 4-year longitudinal study among 24 985 adult women in China.

BJOG

March 2022

Department of Gynecology and Obstetrics, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Objective: To estimate the incidence of urinary incontinence (UI), including its subtypes stress UI (SUI), urgency UI (UUI) and mixed UI (MUI), and to examine risk factors for de novo SUI and UUI in Chinese women.

Design: Nationwide longitudinal study.

Setting: Six geographic regions of China.

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[Risk factors of urinary incontinence in Chinese women based on random forest].

Zhonghua Fu Chan Ke Za Zhi

August 2021

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Obstetric and Gynecologic Diseases, Beijing 100730, China.

To explore the risk factors of urinary incontinence (UI) in China by using random forest algorithm, and to evaluate the predictive effect of each risk factor on UI. A baseline survey with a multistage stratified cluster sampling design was conducted between February 2014 and January 2016, and followed up by telephone from June to December 2018. A total of 55 477 adult women from six provinces of China participated the survey.

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Objective: To determine the prevalence, risk factors and burden of symptomatic pelvic organ prolapse (POP) in adult Chinese women.

Design: A nationwide cross-sectional study.

Setting: Six geographic regions of mainland China.

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Background: Fecal incontinence (FI) has been shown to be a common symptom in Western countries; however, there is few researches focusing on its epidemic condition in Chinese women. We conducted this national population-based epidemiology study to estimate the prevalence and risk factors of FI among adult Chinese women living in urban regions.

Methods: This is a subgroup analysis of a national population-based epidemiology study of FI.

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This study aimed to assess the prevalence and factors associated with pelvic organ prolapse (POP) in a representative sample of Chinese urban women. A total of 29613 Chinese urban women were recruited to this cross-sectional study between February 2014 and March 2016. The prevalence of POP, defined as any stage Ⅱ or higher POP resulting in symptoms, was assessed using questionnaires and physical examinations.

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Analysis between phenotypes and genotypes of inner ear malformation.

Acta Otolaryngol

March 2019

b Department of Otolaryngology-Head and Neck Surgery , Lanzhou University Second Hospital, Lanzhou , China.

Background: The clinical characteristics of LVAS have attracted more and more attention, its audiology and imaging features have also been deeply studied.

Objective: To analyze phenotypes, genotypes of EVA, and find out the relationship between them.

Methods: Sixty EVA patients were tested by audiometry, temporal bone high-resolution CT and inner ear MRI.

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An epidemiologic study of pelvic organ prolapse in rural Chinese women: a population-based sample in China.

Int Urogynecol J

November 2019

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 ShuaiFu Road, Dongcheng District, Beijing, People's Republic of China.

Introduction And Hypothesis: We aimed to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse (POP) in rural China.

Methods: A cross-sectional study of POP was conducted in rural China from February 2014 to March 2016. In total, 25,864 rural women were recruited.

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Lower urinary tract symptoms 7 years after the first delivery: Correlation to the mode of delivery.

Neurourol Urodyn

February 2019

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, P. R. China.

Objective: To investigate the extent of lower urinary tract symptoms (LUTS) during pregnancy and 7 years after birth in primipara and their association with delivery mode history and other factors.

Methods: A longitudinal cohort study was conducted in 12 hospitals representative of the diversity of the seven administrative regions of China. Of 10 098 women recruited at the third trimester, 3862 (38.

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An epidemiologic study on symptomatic pelvic organ prolapse in obese Chinese women: a population-based study in China.

Diabetes Metab Syndr Obes

November 2018

Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China,

Background: The aim of this study was to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse in obese Chinese women.

Subjects And Methods: We performed a secondary analysis of 3,105 obese women from an observational cross-sectional study conducted between February 2014 and March 2016 in Mainland China. The obesity standard in our study was the Chinese standard (body mass index ≥28).

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An epidemiologic study of pelvic organ prolapse in postmenopausal women: a population-based sample in China.

Climacteric

February 2019

a Department of Gynecology and Obstetrics, Peking Union Medical CollegeHospital , Peking Union Medical College, Beijing , People's Republic of China.

Objective: This study aimed to assess the prevalence and factors associated with symptomatic pelvic organ prolapse (POP) in a representative sample of postmenopausal Chinese women.

Methods: A total of 20,008 postmenopausal Chinese women were recruited to this cross-sectional study between February 2014 and March 2016. The prevalence of symptomatic POP, defined as any stage II or higher POP resulting in symptoms, was assessed using questionnaires and physical examinations.

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Background: The Food and Drug Administration recently announced that the use of morcellation may cause fibroids or pelvic dissemination and metastasis of uterine sarcoma; therefore, the use of morcellation is limited in the USA. A large sample study is necessary to assess the proportion of uterine malignant tumors found in patients with laparoscopic myomectomy.

Methods: A national multicenter study was performed in China.

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Spatial memory impairment is associated with hippocampal insulin signals in ovariectomized rats.

PLoS One

November 2015

Institute of Anatomy and Embryology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, Lanzhou, China.

Article Synopsis
  • * Results showed that ovariectomy (removal of ovaries) and the use of an estrogen receptor antagonist (tamoxifen) led to impaired spatial memory and reduced glucose uptake in the hippocampus.
  • * These memory impairments are linked to decreased insulin levels and expression of glucose transporter GLUT4, suggesting that estrogen's role in memory may be related to its effects on insulin signaling and glucose consumption in the brain.
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Objective: At present, blood and skin biopsy tissues are used in the fluorescent in situ hybridization (FISH) test for the diagnosis of Down's syndrome, however, the samples are usually obtained invasively. This study explores the value of oral mucosa cast-off cells in the FISH test, as samples obtained non-invasively, for the diagnosis of this disorder.

Methods: Peripheral blood and oral mucosa cast-off cells were sampled for the FISH test in 16 children with suspected Down's syndrome between March 2010 and March 2011.

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