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Anthrax lethal toxin-induced lung injury and treatment by activating MK2.

J Appl Physiol (1985)

August 2015

Pulmonary, Critical Care, and Sleep Division, Department of Medicine/Tupper Research Institute, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts

Article Synopsis
  • * A rat model injected with LeTx mimics acute lung injury, providing a valuable tool to study treatments for conditions like acute respiratory distress syndrome (ARDS), which other models struggle to replicate.
  • * Researchers have developed a peptide, MK2-AP, that activates a protein to enhance protective effects against LeTx, potentially offering new therapeutic strategies for anthrax and related pulmonary complications.
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