Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury.

To learn whether nitric oxide (NO) inhalation can decrease myocardial ischemia-reperfusion (I/R) injury, we studied a murine model of myocardial infarction (MI). Anesthetized mice underwent left anterior descending coronary artery ligation for 30, 60, or 120 min followed by reperfusion. Mice breathed NO beginning 20 min before reperfusion and continuing thereafter for 24 h.

The measurement of the variation in the surface strains of Achilles tendon grafts using imaging techniques.

Uniaxial tensile tests are commonly used to characterize the structural and material properties of tendons and ligaments. During these tests, the stress and strain distributions applied to the specimen are assumed to be uniform. However, few studies have investigated the strain distributions throughout the tissue.